HMC algorithm with multiple time scale integration and mass preconditioning

We describe a new HMC algorithm variant we have recently introduced and extend the published results by preliminary results of a simulation with a pseudo scalar mass value of about 300 MeV. This new run confirms our expectation that simulations with such pseudo scalar mass values become feasible and affordable with our HMC variant. In addition we discuss simulations from hot and cold starts at a pseudo scalar mass value of about 300 MeV, which we performed in order to test for possible meta-stabilities.Comment: 6 pages, Talk presented at Lattice 2005 (machines and algorithms

Progress using generalized lattice Dirac operators to parametrize the Fixed-Point QCD action

We report on an ongoing project to parametrize the Fixed-Point Dirac operator for massless quarks, using a very general construction which has arbitrarily many fermion offsets and gauge paths, the complete Clifford algebra and satisfies all required symmetries. Optimizing a specific construction with hypercubic fermion offsets, we present some preliminary results.Comment: Lattice 2000 (Improvement), 9 pages, based on a talk by K.H. and a poster by T.J. References adde

The construction of generalized Dirac operators on the lattice

We discuss the steps to construct Dirac operators which have arbitrary fermion offsets, gauge paths, a general structure in Dirac space and satisfy the basic symmetries (gauge symmetry, hermiticity condition, charge conjugation, hypercubic rotations and reflections) on the lattice. We give an extensive set of examples and offer help to add further structures.Comment: 19 pages, latex, maple code attache

What do the recent American Heart Association/American College of Cardiology Foundation Clinical Practice Guidelines tell us about the evolving management of coronary heart disease in older adults?

Biological aging predisposes older adults to increased cardiovascular disease (CHD) and greater disease complexity. Given the high age-related prevalence of CHD and age-related compounding factors, the recently updated American Heart Association/American College of Cardiology Foundation CHD-related guidelines increased their focus on older patients. These guidelines are predominately evidence-based (using data from quality randomized clinical trials) and are organized to delineate medications and procedures that best treat particular cardiovascular diseases. While such rationale and thought work well in young and middle aged adults, they become problematic in patients who are very old. Data pertaining to adults aged ≥ 80 are virtually absent from most randomized clinical trials, and even in the instances when very old patients were included, eligibility criteria typically excluded candidates with co-morbidities and complexities of customary CHD patients. While medications and interventions yielding benefit in clinical trials should theoretically produce the greatest benefits for patients with high intrinsic risk, age-related cardiovascular complexities also increase iatrogenic risks. Navigating between the potential for high benefit and high risk in “evidence-based” cardiovascular management remains a key Geriatric Cardiology challenge. In this review we consider the expanded Geriatric Cardiology content of current guidelines, acknowledging both the progress that has been made, as well as the work that still needs to be accomplished to truly address the patient-centered priorities of older CHD patients

Review

Final published version

Review of the treatment of acute coronary syndrome in elderly patients

Advances in treatment and early revascularization have led to improved outcomes for patients with acute coronary syndrome (ACS). However, elderly ACS patients are less likely to receive evidence-based treatment, including revascularization therapy, due to uncertainty of the associated benefits and risks in this population. This article addresses key issues regarding medical and revascularization therapy in elderly ACS patients based on a review of the medical literature and in concordance with clinical practice guidelines from the American Heart Association (AHA) and the American College of Cardiology (ACC)

Interactive digital signal processor

The Interactive Digital Signal Processor (IDSP) is examined. It consists of a set of time series analysis Operators each of which operates on an input file to produce an output file. The operators can be executed in any order that makes sense and recursively, if desired. The operators are the various algorithms used in digital time series analysis work. User written operators can be easily interfaced to the sysatem. The system can be operated both interactively and in batch mode. In IDSP a file can consist of up to n (currently n=8) simultaneous time series. IDSP currently includes over thirty standard operators that range from Fourier transform operations, design and application of digital filters, eigenvalue analysis, to operators that provide graphical output, allow batch operation, editing and display information