21 research outputs found
Directed flow of antiprotons in Au+Au collisions at AGS
Directed flow of antiprotons is studied in Au+Au collisions at a beam
momentum of 11.5A GeV/c. It is shown that antiproton directed flow is
anti-correlated to proton flow. The measured transverse momentum dependence of
the antiproton flow is compared with predictions of the RQMD event generator.Comment: 16 pages, 6 figure
Two-pion correlations in Au+Au collisions at 10.8 GeV/c per nucleon
Two-particle correlation functions for positive and negative pions have been
measured in Au+Au collisions at 10.8~GeV/c per nucleon. The data were analyzed
using one- and three-dimensional correlation functions. From the results of the
three-dimensional fit the phase space density of pions was calculated. It is
consistent with local thermal equilibrium.Comment: 5 pages RevTeX (including 3 Figures
Proton and Pion Production in Au+Au Collisions at 10.8A GeV/c
We present proton and pion tranverse momentum spectra and rapidity
distributions for Au+Au collisions at 10.8A GeV/c. The proton spectra exhibit
collective transverse flow effects. Evidence of the influence of the Coulomb
interaction from the fireball is found in the pion transverse momentum spectra.
The data are compared with the predictions of the RQMD event generator.Comment: plain tex (revtex), 24 pages Submitted to Phys. Rev.
Hadron yields and spectra in Au+Au collisions at the AGS
Inclusive double differential multiplicities and rapidity density
distributions of hadrons are presented for 10.8 A GeV/c Au+Au collisions as
measured at the AGS by the E877 collaboration. The results indicate that large
amounts of stopping and collective transverse flow effects are present. The
data are also compared to the results from the lighter Si+Al system.Comment: 12 pages, latex, 10 figures, submitted to Nuclear Physics A (Quark
Matter 1996 Proceedings
Two-Proton Correlations from 14.6A GeV/c Si+Pb and 11.5A GeV/c Au+Au Central Collisions
Two-proton correlation functions have been measured in Si+Pb collisions at
14.6A GeV/c and Au+Au collisions at 11.5A GeV/c by the E814/E877 collaboration.
Data are compared with predictions of the transport model RQMD and the source
size is inferred from this comparison. Our analysis shows that, for both
reactions, the characteristic size of the system at freeze-out exceeds the size
of the projectile, suggesting that the fireball created in the collision has
expanded. For Au+Au reactions, the observed centrality dependence of the
two-proton correlation function implies that more central collisions lead to a
larger source sizes.Comment: RevTex, 12 pages, 5 figure
Proton and Pion Production Relative to the Reaction Plane in Au + Au Collisions at AGS Energies
Results are presented of an analysis of proton and charged pion azimuthal
distributions measured with respect to the reaction plane in Au + Au collisions
at a beam momentum of about 11 AGeV/c. The azimuthal anisotropy is studied as a
function of particle rapidity and transverse momentum for different
centralities of the collisions. The triple differential (in rapidity,
transverse momentum, and azimuthal angle) distributions are reconstructed. A
comparison of the results with a previous analysis of charged particle and
transverse energy flow as well as with model predictions is presented.Comment: 23 pages (LaTeX), 12 figure
Recommended from our members
Advancements in the understanding of paclitaxel metabolism in tissue culture
219-23
Recommended from our members
Development of a particle bombardment-mediated transient transformation system for Taxus spp. cells in culture
1180-118
Identification and expression analysis of methyl jasmonate responsive ESTs in paclitaxel producing Taxus cuspidata suspension culture cells
Background Taxol(R)(paclitaxel) promotes microtubule assembly and stabilization and therefore is a potent chemotherapeutic agent against wide range of cancers. Methyl jasmonate (MJ) elicited Taxus cell cultures provide a sustainable option to meet the growing market demand for paclitaxel. Despite its increasing pharmaceutical importance, the molecular genetics of paclitaxel biosynthesis is not fully elucidated. This study focuses on identification of MJ responsive transcripts in cultured Taxus cells using PCR-based suppression subtractive hybridization (SSH) to identify genes involved in global pathway control. Results Six separate SSH cDNA libraries of paclitaxel-accumulating Taxus cuspidata P991 cell lines were constructed at three different post-elicitation time points (6h, 18h and 5 day) to identify genes that are either induced or suppressed in response to MJ. Sequencing of 576 differentially screened clones from the SSH libraries resulted in 331 unigenes. Functional annotation and Gene Ontology (GO) analysis of up-regulated EST libraries showed enrichment of several known paclitaxel biosynthetic genes and novel transcripts that may be involved in MJ-signaling, taxane transport, or taxane degradation. Macroarray analysis of these identified genes unravelled global regulatory expression of these transcripts. Semi-quantitative RT-PCR analysis of a set of 12 candidate genes further confirmed the MJ-induced gene expression in a high paclitaxel accumulating Taxus cuspidata P93AF cell line. Conclusions This study elucidates the global temporal expression kinetics of MJ responsive genes in Taxus suspension cell culture. Functional characterization of the novel genes identified in this study will further enhance the understanding of paclitaxel biosynthesis, taxane transport and degradation