Assessment of antioxidant activity of Ocimum sanctum in healing of thermal burn wound with and without supportive treatment of silver sulfadiazine in rabbits

Background: Burns remain a major public health issue all over the world, especially in developing countries. Pseudomonas aeruginosa is a major cause of infection and death in patients with severe burns.  So, there is a need to develop drugs which will decrease complications and prevent infections more effectively than the presently used drugs.Methods: Ocimum sanctum, ointment silver sulfadiazine and 24 Rabbits were used in this study. Animals were acclimatized and divided randomly into 04 groups of 06 animals each. After producing partial thickness burn wound ointment silver sulfadiazine was applied daily on the burn wound and Ocimum sanctum was administered orally once daily. Healing was assessed by wound contraction and Oxidative stress and Antioxidant Activity were measured by Malondialdehyde and Superoxide dismutase respectively. Results were analysed by student’s ‘t’ test, one way ANOVA followed by Dennett’s test. P values <0.05 were considered statistically significant.Results: At the end of treatment (After 28th Day) Group treated with ointment silver sulfadiazine+Ocimum sanctum showed  maximum Percentage of wound contraction (93.17±4.34), maximum decrease of MDA percentage (0.30±0.02 nmol/ml) and maximum increase of SOD percentage (0.0045±0.0002 IU/gm of Hb).Conclusions: Most effective treatment for burn wound healing in this study was ointment silver sulfadiazine+Ocimum sanctum

Observation of Mixed Alkali Like Behaviour by Fluorine Ion in Mixed Alkali Oxyfluro Vanadate Glasses: Analysis from Conductivity Measurements

In this communication we report the fluorine ion dynamics in mixed alkali oxyfluro vanadate glasses. We have measured the electrical conductivity using impedance spectroscopy technique Room temperature conductivity falls to 5 orders of magnitude from its single alkali values at 33 mol% of rubidium concentration. We have also estimated the distance between similar mobile ions using the density values. Assuming this distance as the hopping distance between the similar ions we have estimated the anionic (Fluorine ion in our case) conductivity. It is observed that the fluorine ion dynamics mimics the mixed alkali effect and scales as the onset frequency f0.Comment: submitted to DAE-SSDP 2018 Indi

SourcererCC: Scaling Code Clone Detection to Big Code

Despite a decade of active research, there is a marked lack in clone detectors that scale to very large repositories of source code, in particular for detecting near-miss clones where significant editing activities may take place in the cloned code. We present SourcererCC, a token-based clone detector that targets three clone types, and exploits an index to achieve scalability to large inter-project repositories using a standard workstation. SourcererCC uses an optimized inverted-index to quickly query the potential clones of a given code block. Filtering heuristics based on token ordering are used to significantly reduce the size of the index, the number of code-block comparisons needed to detect the clones, as well as the number of required token-comparisons needed to judge a potential clone. We evaluate the scalability, execution time, recall and precision of SourcererCC, and compare it to four publicly available and state-of-the-art tools. To measure recall, we use two recent benchmarks, (1) a large benchmark of real clones, BigCloneBench, and (2) a Mutation/Injection-based framework of thousands of fine-grained artificial clones. We find SourcererCC has both high recall and precision, and is able to scale to a large inter-project repository (250MLOC) using a standard workstation.Comment: Accepted for publication at ICSE'16 (preprint, unrevised

Channel routing optimization using a genetic algorithm

A modified approach for the application of Genetic Algorithm (GA) to the Channel Routing Problem has been proposed. The code based on the algorithm proposed in [1] has been implemented for the GA procedures of Initial Population Generation, Crossover, Mutation and Selection. A few improvements over the existing work have been made and the results so far obtained have been encouraging. Further experimentation is being done on the algorithm and other ideas generated during the development of the code are being implemented for faster convergence of the algorithm and for generation of more efficient results. Also application of variations of the GA technique like Vector GA and even other computationally intelligent techniques like Particle Swarm Optimization to the channel routing problem is being thought of

A Survey on Modeling Line Commutated Converter HVDC Transmission Systems

This paper review about the dynamic phasor model of a line-commutated converter (LCC) high-voltage direct current (HVDC) transmission system. The mathematical definition and properties of dynamic phasors are utilized to model both the dc-side and the ac-side of a LCC-HVDC transmission system as well as 6-pulse Graetz Bridge, which is the building block of such a system. The developed model includes low-frequency dynamics of the systems, i.e., fundamental frequency component (50 Hz) at the ac-side and dc component at the dc-side, and removes high-frequency transients. The developed model, however, is capable of accommodating higher harmonics if necessary. The model is also able to simulate the system during abnormal modes of operations such as unbalanced operation and commutation failure. In order to develop the dynamic phasor model of a line-commutated converter, the concept of switching functions is utilized. The developed model is capable of capturing large-signal transients of the system as well as steady state operating conditions. The model can be used in order to decrease the computational intensity of LCC-HVDC simulations