A study on health profile of geriatric population in an urban slum of bijapur

Background: Advances in medical field have increased the longevity of people by reducing morbidity and mortality to a great extent. With the increase in longevity, problems related to old age have also increased. These problems are more confounded by social factors. Objective: To assess the various health problems faced by elderly people and suggest the remedial measures so that effective preventive and promotive measures can be implemented. Methodology: Community based cross-sectional study of the elderly persons residing in an urban slum of Bijapur. Results: Among acute health problems most common were arthritis (39%) and bronchitis (20.8%). Most common chronic illness observed was respiratory illness 19% (COPD and asthma) fallowed by visual impairment (11.5%), arthritis (11.1%), and hypertension (9.1%) Mini Mental State Examination (MMSE) showed that majority of respondents 297 (60%) were having the normal score. Conclusion: The pattern of geriatric health problems have different characteristics and hence require a specific type of screening programme based on the finding of various geriatric health studies

Extramedullary leukemia in children presenting with proptosis

<p>Abstract</p> <p>Background</p> <p>We highlight the orbital manifestations of acute myeloid leukemia and the role of peripheral blood smear in the diagnosis of these cases. A total of 12 patients who presented with proptosis and were subsequently diagnosed to have acute myeloid leukemia based on incision biopsy or peripheral blood smear were included in the study.</p> <p>Results</p> <p>A retrospective review of all cases of acute myeloid leukemia presenting to the Orbital clinic was performed. The age at presentation, gender, presenting features, duration of symptoms and fundus features were noted. In addition the temporal relationship of the orbital disease to the diagnosis of leukemia, laterality, location of the orbital mass, imaging features and the diagnostic tools used to diagnose leukemia were noted. The median age at presentation was 6 years. The male: female ratio was 0.7:1. None of these patients had been diagnosed earlier as having acute myeloid leukemia. The presenting features included proptosis in all patients, orbital mass in 5 (41.7%), visual symptoms in 2 (16.7%) and subconjunctival hemorrhage in one patient (8.3%). A diagnosis of acute myeloid leukemia was established by incision biopsy in 4 patients, subsequently confirmed by peripheral blood smear testing and bone marrow biopsy in 2 patients which revealed the presence of systemic involvement. Imprint smears of the biopsy identified blasts in 2 of 4 cases. In 8 patients presenting with ocular manifestations, diagnosis was established by peripheral blood smear examination alone which revealed a diagnosis of acute myeloid leukemia.</p> <p>Conclusion</p> <p>A peripheral blood smear should be performed in all cases of sudden onset proptosis or an orbital mass in children and young adults along with an orbital biopsy. It can always be complemented with a bone marrow biopsy especially in cases of aleukemic leukemia or when the blood smear is inconclusive.</p

SLOW INCREASING FUNCTIONS AND THEIR APPLICATIONS TO SOME PROBLEMS IN NUMBER THEORY

This article commences with a definition of slow increasing function and moves on to delineate a few properties of slow increasing functions. Besides, several applications in some problems of number theory using the theory of slow increasing functions are also presented to show how useful these functions prove in solving complex problems

Genetic Variability in Napier Grass (\u3cem\u3ePennisetum purpureum\u3c/em\u3e) Germplasm Conserved at ICRISAT Genebank

Napier grass or elephant grass [Pennisetum purpureum Schum.] is an important forage crop in tropical and sub-tropical regions valued for its high biomass production, perennial nature, pest resistance, and forage quality. It is a unique grass species with high dry matter, which sustains its utilization for direct animal grazing and as a feed complement during drought periods. It has additional advantages like preventing soil erosion and improving soil fertility. Napier grass also has potential for bioenergy production and conversion to alcohol or methane due to its rapid growth and degradable biomass characteristics. The present study was planned to assess the genetic variability among purpureum germplasm conserved at ICRISAT genebank, Patancheru for their potential utilization in development of forage varieties and bajranapier hybrids

An overview of health concerns among elderly population

Background: Urbanisation, nuclearisation of family, migration, and dual career families are making care of the elderly more and more of a personal and social problem in India. Objective: Assess the concerns about health issues among elderly people. Methodology: Community based cross-sectional study. Results: 64.4% of the elders were treated well and about 22.9% were treated very well during illness. 86.3% were consulted during illness. Son was the care taker in 55.6% of study subjects. 70.6% of elderly were consulted to allopathic practitioners / Govt Hospitals. Conclusion: It is the responsibility of family to look after elderly in respectful manner, especially during illness. The government should frame policies and provide social and economical security to elders

MOSAIC: Multi-Object Segmented Arbitrary Stylization Using CLIP

Style transfer driven by text prompts paved a new path for creatively stylizing the images without collecting an actual style image. Despite having promising results, with text-driven stylization, the user has no control over the stylization. If a user wants to create an artistic image, the user requires fine control over the stylization of various entities individually in the content image, which is not addressed by the current state-of-the-art approaches. On the other hand, diffusion style transfer methods also suffer from the same issue because the regional stylization control over the stylized output is ineffective. To address this problem, We propose a new method Multi-Object Segmented Arbitrary Stylization Using CLIP (MOSAIC), that can apply styles to different objects in the image based on the context extracted from the input prompt. Text-based segmentation and stylization modules which are based on vision transformer architecture, were used to segment and stylize the objects. Our method can extend to any arbitrary objects, styles and produce high-quality images compared to the current state of art methods. To our knowledge, this is the first attempt to perform text-guided arbitrary object-wise stylization. We demonstrate the effectiveness of our approach through qualitative and quantitative analysis, showing that it can generate visually appealing stylized images with enhanced control over stylization and the ability to generalize to unseen object classes.Comment: Camera ready, New Ideas in Vision Transformers workshop, ICCV 202

Histidylated lipid-modified sendai viral envelopes mediate enhanced membrane fusion and potentiate targeted gene delivery

Recent studies have demonstrated that covalent grafting of a single histidine residue into a twin-chain aliphatic hydrocarbon compound enhances its endosome-disrupting properties and thereby generates an excellent DNA transfection system. Significant increase in gene delivery efficiencies has thus been obtained by using endosome-disrupting multiple histidine functionalities in the molecular architecture of various cationic polymers. To take advantage of this unique feature, we have incorporated L-histidine (N,N-di-n-hexadecylamine) ethylamide (L(H)) in the membrane of hepatocyte-specific Sendai virosomes containing only the fusion protein (F-virosomes (Process for Producing a Targeted Gene (Sarkar, D. P., Ramani, K., Bora, R. S., Kumar, M., and Tyagi, S. K. (November 4, 1997) U. S. Patent 5,683,866))). Such L(H)-modified virosomal envelopes were four times more (p &lt;0.001) active in terms of fusion with its target cell membrane. On the other hand, the presence of L(H) in reconstituted influenza and vesicular stomatitis virus envelopes failed to enhance spike glycoprotein-induced membrane fusion with host cell membrane. Circular dichroism and limited proteolysis experiments with F-virosomes indicated that the presence of L(H) leads to conformational changes in the F protein. The molecular mechanism associated with the increased membrane fusion induced by L(H) has been addressed in the light of fusion-competent conformational change in F protein. Such enhancement of fusion resulted in a highly efficient gene delivery system specific for liver cells in culture and in whole animals

Classification of Targets Using Statistical Features from Range FFT of mmWave FMCW Radars

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