11,375 research outputs found

    Grown-in defects and defects produced by 1-Me electron irradiated in Al0.3Ga0.7As P-N junction solar cells

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    Studies of grown-in defects and defects produced by the one-MeV electron irradiation in Al sub 0.3 Ga sub 0.7As p-n junction solar cells fabricated by liquid phase epitaxial (LPE) technique were made for the unirradiated and one-MeV electron irradiated samples, using DLTS and C-V methods. Defect and recombination parameters such as energy level, defect density, carrier capture cross sections and lifetimes were determined for various growth, annealing, and irradiation conditions

    Metabolism of ticagrelor in patients with acute coronary syndromes.

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    © The Author(s) 2018Ticagrelor is a state-of-the-art antiplatelet agent used for the treatment of patients with acute coronary syndromes (ACS). Unlike remaining oral P2Y12 receptor inhibitors ticagrelor does not require metabolic activation to exert its antiplatelet action. Still, ticagrelor is extensively metabolized by hepatic CYP3A enzymes, and AR-C124910XX is its only active metabolite. A post hoc analysis of patient-level (n = 117) pharmacokinetic data pooled from two prospective studies was performed to identify clinical characteristics affecting the degree of AR-C124910XX formation during the first six hours after 180 mg ticagrelor loading dose in the setting of ACS. Both linear and multiple regression analyses indicated that ACS patients presenting with ST-elevation myocardial infarction or suffering from diabetes mellitus are more likely to have decreased rate of ticagrelor metabolism during the acute phase of ACS. Administration of morphine during ACS was found to negatively influence transformation of ticagrelor into AR-C124910XX when assessed with linear regression analysis, but not with multiple regression analysis. On the other hand, smoking appears to increase the degree of ticagrelor transformation in ACS patients. Mechanisms underlying our findings and their clinical significance warrant further research.Peer reviewedFinal Published versio

    First order magnetic transition in CeFe2_2 alloys: Phase-coexistence and metastability

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    First order ferromagnetic (FM) to antiferromagnetic (AFM) phase transition in doped-CeFe2_2 alloys is studied with micro-Hall probe technique. Clear visual evidence of magnetic phase-coexistence on micrometer scales and the evolution of this phase-coexistence as a function of temperature, magnetic field and time across the first order FM-AFM transition is presented. Such phase-coexistence and metastability arise as natural consequence of an intrinsic disorder-influenced first order transition. Generality of this phenomena involving other classes of materials is discussed.Comment: 11 pages of text and 3 figure

    Broadband spin-controlled focusing via logarithmic-spiral nanoslits of varying width

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    This work presents analytical, numerical and experimental demonstrations of light diffracted through a logarithmic spiral (LS) nanoslit, which forms a type of switchable and focus-tunable structure. Owing to a strong dependence on the incident photon spin, the proposed LS-nanoslit converges incoming light of opposite handedness (to that of the LS-nanoslit) into a confined subwavelength spot, while it shapes light with similar chirality into a donut-like intensity profile. Benefitting from the varying width of the LS-nanoslit, different incident wavelengths interfere constructively at different positions, i.e., the focal length shifts from 7.5 μm (at λ = 632.8 nm) to 10 μm (at λ = 488 nm), which opens up new opportunities for tuning and spatially separating broadband light at the micrometer scale

    Predictive Modelling Using Unstructured Data From Online Forums: A Case Study on E-cigarette Users

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    In the age of the digital economy, social media, forums and other online platforms have played active parts in our daily activities. The amount of data digitized and recorded in these platforms have surged exponentially. Many believed that this underexplored unstructured data sources have huge potential in offering insights to policy makers and companies. This paper aims to propose a hybrid approach using inductive and deductive reasoning to identify motivational factors to use e-cigarettes for predictive modelling. A total of 790 comments and discussions relevant to e-cigarette use and motivations to use e-cigarette were scraped and stored from online forums like Reddit, Vapingunderground and e-cigarette-forum. A series of text analytics were conducted on the text corpus and the cluster analysis enabled us to build a predictive model. Using Bayesian Structural Equation Modelling, we concluded that the constructs derived by clustering, i.e. Cost and Convenience and Enjoyment, have significant associations with smokers trying to quit smoking. While health-related issues were inherent to the notion of quitting smoking, enjoyment, cost and convenience were motivational factors which will generate favourable response towards quitting smoking. The findings showed encouraging results from a methodological standpoint and offered insights to policy makers and companies on health-related issues pertaining to the use of e-cigarettes

    The location of an active nucleus and a shadow of a tidal tail in the ULIRG Mrk 273

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    Analysis of data from the Chandra X-ray Observatory for the double nucleus ULIRG Mrk 273 reveals an absorbed hard X-ray source coincident with the southwest nucleus, implying that this unresolved, near-infrared source is where an active nucleus resides, while the northern nuclear region contains a powerful starburst that dominates the far infrared luminosity. There is evidence of a slight image extension in the 6–7 keV band, where an Fe K line is present, towards the northern nucleus. A large-scale, diffuse emission nebula detected in soft X-rays contains a dark lane that spatially coincides with a high surface-brightness tidal tail extending ~50 arcsec (40 kpc) to the south. The soft X-ray source is likely located behind the tidal tail, which absorbs X-ray photons along the line of sight. The estimated column density of cold gas in the tidal tail responsible for shadowing the soft X-rays is N_H ≥ 6 × 10^(21) cm^(-2), consistent with the tidal tail having an edge-on orientation

    At the limits of ‘Capability’: The sexual and reproductive health of women migrant workers in Malaysia

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    Despite the centrality of sexual and reproductive health (SRH) to UN Sustainable Development Goals (SDGs), women migrant workers in Malaysia face an environment inimical to their SRH needs. Drawing on qualitative case study material, we present the first empirical application of the Capability Approach (CA) to explore the reproductive health needs of women migrant workers in a developing country, offering an original analysis of the capability for SRH of these women. Specifically, we explore the resources available to them; their opportunities and freedoms (‘capabilities’); and factors which mediate transformation of resources into capability sets (‘conversion factors’). While SRH information and healthcare is notionally available, women migrant workers face multiple challenges in converting resources into functionings, constraining the achievement of capability for SRH. Challenges include language barriers, personal beliefs, power relations between workers and employers and the consequences of current migration policy. We consider the scale of the challenges facing these women in securing SRH rights, the difficulties of operationalising the CA within such a setting, and the implications of our findings for the adequacy of the CA in supporting marginalised populations

    Inequalities Detecting Quantum Entanglement for 2d2\otimes d Systems

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    We present a set of inequalities for detecting quantum entanglement of 2d2\otimes d quantum states. For 222\otimes 2 and 232\otimes 3 systems, the inequalities give rise to sufficient and necessary separability conditions for both pure and mixed states. For the case of d>3d>3, these inequalities are necessary conditions for separability, which detect all entangled states that are not positive under partial transposition and even some entangled states with positive partial transposition. These inequalities are given by mean values of local observables and present an experimental way of detecting the quantum entanglement of 2d2\otimes d quantum states and even multi-qubit pure states.Comment: 6 page

    Processing of polarimetric SAR data for soil moisture estimation over Mahantango watershed area

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    Microwave remote sensing technique has a high potential for measuring soil moisture due to the large contrast in dielectric constant of dry and wet soils. Recent work by Pults et al. demonstrated the use of X/C-band data for quantitative surface soil moisture extraction from Airborne Synthetic Aperture Radar (SAR) system. Similar technique was adopted using polarimetric SAR data acquired with the JPL-AIRSAR system over the Mahantango watershed area in central Pennsylvania during July 1990. The data sets reported include C-, L-, and P-bands of 10, 13, 15, and 17 July 1990
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