182 research outputs found

    Media and Audio Practices: a Search for Philosophical Background of Analysis

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    Analysis of sound-based media artistic practices will serve as a case of a new media paradigm of contemporary art. This aim is informed by transintermedia, the multimodal nature of these practices that synthesize audio, visual, and proprioceptive forms of artistic communication in today’s media environment, as well as by the integrative nature of the multimedia interactive catalogue/archive that allows one to present on a platform individual projects, their documentation, analysis, geography, authorship, and reception, as well as philosophical reflection by the researchers. Сatalogization, systematic description and philosophical analysis of sound-based media artistic practices will allow for the effective support and promotion of media-art and sound-art practices in the framework of new programs and projects, plans for the development of urban and regional artistic and acoustic social and cultural environments.This research was financially supported by the Russian Foundation for Basic Research (Grant No. 17-29-09136/20 “Multilingualism in the era of post-literacy: Philosophical and cultural studies and methodological and pedagogical development of a multilingual education model”)

    Steady state of atoms in a resonant field with elliptical polarization

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    We present a complete set of analytical and invariant expressions for the steady-state density matrix of atoms in a resonant radiation field with arbitrary intensity and polarization. The field drives the closed dipole transition with arbitrary values of the angular momenta JgJ_{g} and JeJ_{e} of the ground and excited state. The steady-state density matrix is expressed in terms of spherical harmonics of a complex direction given by the field polarization vector. The generalization to the case of broad-band radiation is given. We indicate various applications of these results.Comment: revtex, 26 pages, including 3 eps figures; PRA accepted for publication;v2 three typos are fixe

    Breakup reaction models for two- and three-cluster projectiles

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    Breakup reactions are one of the main tools for the study of exotic nuclei, and in particular of their continuum. In order to get valuable information from measurements, a precise reaction model coupled to a fair description of the projectile is needed. We assume that the projectile initially possesses a cluster structure, which is revealed by the dissociation process. This structure is described by a few-body Hamiltonian involving effective forces between the clusters. Within this assumption, we review various reaction models. In semiclassical models, the projectile-target relative motion is described by a classical trajectory and the reaction properties are deduced by solving a time-dependent Schroedinger equation. We then describe the principle and variants of the eikonal approximation: the dynamical eikonal approximation, the standard eikonal approximation, and a corrected version avoiding Coulomb divergence. Finally, we present the continuum-discretized coupled-channel method (CDCC), in which the Schroedinger equation is solved with the projectile continuum approximated by square-integrable states. These models are first illustrated by applications to two-cluster projectiles for studies of nuclei far from stability and of reactions useful in astrophysics. Recent extensions to three-cluster projectiles, like two-neutron halo nuclei, are then presented and discussed. We end this review with some views of the future in breakup-reaction theory.Comment: Will constitute a chapter of "Clusters in Nuclei - Vol.2." to be published as a volume of "Lecture Notes in Physics" (Springer

    Multiparametric determination of genes and their point mutations for identification of beta-lactamases

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    ЭФФЕКТИВНОСТЬ ГИПЕРТОНИЧЕСКОЙ МОРСКОЙ ВОДЫ В ТЕРАПИИ ИНФЕКЦИОННОГО МОНОНУКЛЕОЗА У ДЕТЕЙ

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    An enlargement in pharyngeal lymphoid ring accompanies infectious mononucleosis. This can significantly degrade the quality of life of a sick child. When nasopharyngeal and palatine tonsils are irrigated with saline seawater with aloe and chamomile hypertonic, the airway patency restores on average 2 days faster than in conventional treatment with decongestants. The condition of the pharynx normalizes 3,5 days faster in comparison with treatment by local antiseptics. The complex preparation with a broad spectrum of activity can improve patient’s commitment to therapy and significantly reduce expenses for outpatient treatment.Инфекционный мононуклеоз сопровождается увеличением лимфоидной ткани глоточного кольца, что может значительно ухудшать качество жизни больного ребенка. При орошении носоглоточной и небных миндалин натуральной гипертонической морской водой с экстрактами алоэ и ромашки проходимость дыхательных путей восстанавливается в среднем на 2 дня раньше, чем при назначении топических деконгестантов, а фарингоскопическая картина нормализуется на 3,5 дня быстрее, чем при использовании местных антисептиков. Комплексный препарат с широким спектром действия позволяет повысить приверженность пациентов к терапии и существенно снизить материальные затраты на лечение в амбулаторных условиях

    Prevalence and correlates of restless legs syndrome in men living with HIV

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    Background Data on the prevalence and correlates of restless legs syndrome (RLS) in people with HIV are limited. This study sought to determine the prevalence of RLS, associated clinical correlates, and characterize sleep-related differences in men with and without HIV. Methods Sleep-related data were collected in men who have sex with men participating in the Multicenter AIDS Cohort Study (MACS). Demographic, health behaviors, HIV status, comorbidities, and serological data were obtained from the MACS visit coinciding with sleep assessments. Participants completed questionnaires, home polysomnography, and wrist actigraphy. RLS status was determined with the Cambridge-Hopkins RLS questionnaire. RLS prevalence was compared in men with and without HIV. Multinomial logistic regression was used to examine correlates of RLS among all participants and men with HIV alone. Sleep-related differences were examined in men with and without HIV by RLS status. Results The sample consisted of 942 men (56% HIV+; mean age 57 years; 69% white). The prevalence of definite RLS was comparable in men with and without HIV (9.1% vs 8.7%). In multinomial regression, HIV status was not associated with RLS prevalence. However, white race, anemia, depression, and antidepressant use were each independently associated with RLS. HIV disease duration was also associated with RLS. Men with HIV and RLS reported poorer sleep quality, greater sleepiness, and had worse objective sleep efficiency/ fragmentation than men without HIV/RLS. Conclusions The prevalence of RLS in men with and without HIV was similar. Screening for RLS may be considered among people with HIV with insomnia and with long-standing disease

    Peptide-MHC heterodimers show that thymic positive selection requires a more restricted set of self-peptides than negative selection

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    T cell selection and maturation in the thymus depends on the interactions between T cell receptors (TCRs) and different self-peptide–major histocompatibility complex (pMHC) molecules. We show that the affinity of the OT-I TCR for its endogenous positively selecting ligands, Catnb-H-2Kb and Cappa1-H-2Kb, is significantly lower than for previously reported positively selecting altered peptide ligands. To understand how these extremely weak endogenous ligands produce signals in maturing thymocytes, we generated soluble monomeric and dimeric peptide–H-2Kb ligands. Soluble monomeric ovalbumin (OVA)-Kb molecules elicited no detectable signaling in OT-I thymocytes, whereas heterodimers of OVA-Kb paired with positively selecting or nonselecting endogenous peptides, but not an engineered null peptide, induced deletion. In contrast, dimer-induced positive selection was much more sensitive to the identity of the partner peptide. Catnb-Kb–Catnb-Kb homodimers, but not heterodimers of Catnb-Kb paired with a nonselecting peptide-Kb, induced positive selection, even though both ligands bind the OT-I TCR with detectable affinity. Thus, both positive and negative selection can be driven by dimeric but not monomeric ligands. In addition, positive selection has much more stringent requirements for the partner self-pMHC
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