Survey on Hardware Implementation of Montgomery Modular

This paper gives the information regarding different methodology for modular multiplication with the modification of Montgomery algorithm. Montgomery multiplier proved to be more efficient multiplier which replaces division by the modulus with series of shifting by a number and an adder block. For larger number of bits, Modular multiplication takes more time to compute and also takes more area of the chip. Different methods ensure more speed and less chip size of the system. The speed of the multiplier is decided by the multiplier. Here three modified Montgomery algorithm discussed with their output compared with each other. The three methods are Iterative architecture, Montgomery multiplier for faster Cryptography and Vedic multipliers used in Montgomery algorithm for multiplication.Here three boards have been used for the analysis and they are Altera DE2-70, FPGA board Virtex 6 and Kintex 7

Survey on Hardware Implementation of Montgomery Modular

This paper gives the information regarding different methodology for modular multiplication with the modification of Montgomery algorithm. Montgomery multiplier proved to be more efficient multiplier which replaces division by the modulus with series of shifting by a number and an adder block. For larger number of bits, Modular multiplication takes more time to compute and also takes more area of the chip. Different methods ensure more speed and less chip size of the system. The speed of the multiplier is decided by the multiplier. Here three modified Montgomery algorithm discussed with their output compared with each other. The three methods are Iterative architecture, Montgomery multiplier for faster Cryptography and Vedic multipliers used in Montgomery algorithm for multiplication.Here three boards have been used for the analysis and they are Altera DE2-70, FPGA board Virtex 6 and Kintex 7

New drug development in India

This article does not have an abstract

Schiff’s base Fufural Phenylhydrazone as a Potential Corrosion Inhibitor for Mild Steel in Hydrochloric Acid Solution

Heterocyclic Schiff base furfural phenylhydrazone [FPH] was prepared and formulated as a corrosion inhibitor for mild steel in 2M hydrochloric acid solution. Mass change measurement and electrochemical methods adapted to study the effectiveness of the FPH during the corrosion process. FPH inhibitor protected 94.53 % corrosion of mild steel at optimum inhibitor strength of 0.0007 M at 303 ±1 K. Route of corrosion protection was interpreted through adsorption of FPH molecules on specimen surfaces in acid solution. Nature of the adsorption was established via Langmuir adsorption isotherm. Stability of the inhibitor was investigated with higher temperatures. Tafel polarization curves revealed, FPH molecules exhibit mixed nature of inhibitor. SEM and AFM images suggested that corroded specimen surface was severely affected in free acid comparatively in presence of FPH inhibitor. FT-IR analysis proved that, chemical interaction takes place between specimen surface atoms with FPH molecules and established chemical bond between them

Critical Role of FLRT1 Phosphorylation in the Interdependent Regulation of FLRT1 Function and FGF Receptor Signalling

Background Fibronectin leucine rich transmembrane (FLRT) proteins have dual properties as regulators of cell adhesion and potentiators of fibroblast growth factor (FGF) mediated signalling. The mechanism by which the latter is achieved is still unknown and is the subject of this investigation. Principal Findings Here we show that FLRT1 is a target for tyrosine phosphorylation mediated by FGFR1 and implicate a non-receptor Src family kinase (SFK). We identify the target tyrosine residues in the cytoplasmic domain of FLRT1 and show that these are not direct substrates for Src kinase suggesting that the SFK may exert effects via potentiation of FGFR1 kinase activity. We show that whilst FLRT1 expression results in a ligand-dependent elevation of MAP kinase activity, a mutant version of FLRT1, defective as an FGFR1 kinase substrate (Y3F-FLRT1), has the property of eliciting ligand-independent chronic activation of the MAP kinase pathway which is suppressed by pharmacological inhibition of either FGFR1 or Src kinase. Functional investigation of FGFR1 and FLRT1 signalling in SH-SY5Y neuroblastoma cells reveals that FLRT1 alone acts to induce a multi-polar phenotype whereas the combination of FLRT1 and FGFR activation, or expression of Y3F-FLRT1, acts to induce neurite outgrowth via MAPK activation. Similar results were obtained in a dendrite outgrowth assay in primary hippocampal neurons. We also show that FGFR1, FLRT1 and activated Src are co-localized and this complex is trafficked toward the soma of the cell. The presence of Y3F-FLRT1 rather than FLRT1 resulted in prolonged localization of this complex within the neuritic arbour. Conclusions This study shows that the phosphorylation state of FLRT1, which is itself FGFR1 dependent, may play a critical role in the potentiation of FGFR1 signalling and may also depend on a SFK-dependent phosphorylation mechanism acting via the FGFR. This is consistent with an ‘in vivo’ role for FLRT1 regulation of FGF signalling via SFKs. Furthermore, the phosphorylation-dependent futile cycle mechanism controlling FGFR1 signalling is concurrently crucial for regulation of FLRT1-mediated neurite outgrowth

Mooring forces in horizontal interlaced multilayered Floating pipe breakwater with three layers

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

Synthesis and metal complexation of chiral 3-mono-or 3, 3-bis-allyl-2-hydroxypyrrolopyrazine-1, 4-diones

A novel synthesis of chiral cyclic hydroxamic acids (4, 6, 8 and 10) related to cyclodipeptides is described. The crucial reduction of the nitro group of the N-nitroacetyl derivatives of (S)-α-amino acid esters is brought about by zinc-aq. ammonium chloride. The FeIII and CuII complexes of one such cyclic hydroxamic acid 10a have been prepared and their DNAse activity investigated

The fork protection complex recruits FACT to reorganize nucleosomes during replication

Chromosome replication depends on efficient removal of nucleosomes by accessory factors to ensure rapid access to genomic information. Here, we show this process requires recruitment of the nucleosome reorganization activity of the histone chaperone FACT. Using single-molecule FRET, we demonstrate that reorganization of nucleosomal DNA by FACT requires coordinated engagement by the middle and C-terminal domains of Spt16 and Pob3 but does not require the N-terminus of Spt16. Using structure-guided pulldowns, we demonstrate instead that the N-terminal region is critical for recruitment by the fork protection complex subunit Tof1. Using in vitro chromatin replication assays, we confirm the importance of these interactions for robust replication. Our findings support a mechanism in which nucleosomes are removed through the coordinated engagement of multiple FACT domains positioned at the replication fork by the fork protection complex

Investigation of Laurus Tamala leaves extract as an environmentally acceptable corrosion inhibitor for soft steel in 1M HCl: Electrochemical, DFT, and surface characterization techniques

Laurus Tamala leaves extract (LTLE) has been employed as a soft steel corrosion inhibitor in a 1M Hydrochloric acid media. Chemical (weight loss) and electrochemical investigations were carried out to assess the corrosion rate and percentage inhibition efficiency of the extract. The electrochemical polarization results have demonstrated that plant leaves extract functions as a mixed type inhibitor. The stability of the inhibitor is tested at elevated temperatures by weight loss method. The corrosion inhibition mechanism is interpreted through adsorption mechanism, and the LTLE components has obeyed the Langmuir adsorption isotherm for soft steel. The interaction of the components of the extract is assessed through FT-IR technique. The surface morphology, roughness and hydrophobicity in presence and absence of the extract have been characterized through SEM, AFM and water contact angle techniques respectively. The highest inhibitory efficiency is 96.21% for 24 h as recorded by weight loss method. Additionally, the DFT computations has revealed the inhibitor’s adsorption through electron donor-acceptor interactions