Improving the sentence writing fluency of a student with attention deficit hyperactivity disorder and speech/language impairment: A pilot study

The skill of sentence writing – the composition of connected text into sentence types understandable to readers – is foundational to written expression. Unfortunately, many students with learning disabilities – particularly those with attention deficit hyperactivity disorder (ADHD) and speech and/or language impairment (S/LI) – struggle to develop sentence writing and its multiple, related skills. Using a single-baseline design, we studied effects of a supplemental writing intervention on one elementary-aged student with comorbid ADHD and S/LI. The intervention entailed delivery of a writing fluency intervention with several antecedent- and consequence-based components: explicit instruction, fluency practice, a reinforcer survey, and contingent reinforcement. The participating student improved his accuracy and speed of sentence writing during intervention. Results are discussed within the context of text writing fluency and frameworks of academic interventions for students with ADHD and S/LI

Exploring Patterns of Dynamic Size Changes of Lesions after Hepatic Microwave Ablation in an In Vivo Porcine Model

Microwave ablation (MWA) is a type of minimally invasive cancer therapy that uses heat to induce necrosis in solid tumours. Inter- and post-ablational size changes can influence the accuracy of control imaging, posing a risk of incomplete ablation. The present study aims to explore post-ablation 3D size dynamics in vivo using computed tomography (CT). Ten MWA datasets obtained in nine healthy pigs were used. Lesions were subdivided along the z-axis with an additional planar subdivision into eight subsections. The volume of the subsections was analysed over different time points, subsequently colour-coded and three-dimensionally visualized. A locally weighted polynomial regression model (LOESS) was applied to describe overall size changes, and Student's t-tests were used to assess statistical significance of size changes. The 3D analysis showed heterogeneous volume changes with multiple small changes at the lesion margins over all time points. The changes were pronounced at the upper and lower lesion edges and characterized by initially eccentric, opposite swelling, followed by shrinkage. In the middle parts of the lesion, we observed less dimensional variations over the different time points. LOESS revealed a hyperbolic pattern for the volumetric changes with an initially significant volume increase of 11.6% (111.6% of the original volume) over the first 32 minutes, followed by a continuous decrease to 96% of the original volume (p < 0.05)

Improved Visualization of the Necrotic Zone after Microwave Ablation Using Computed Tomography Volume Perfusion in an In Vivo Porcine Model

After hepatic microwave ablation, the differentiation between fully necrotic and persistent vital tissue through contrast enhanced CT remains a clinical challenge. Therefore, there is a need to evaluate new imaging modalities, such as CT perfusion (CTP) to improve the visualization of coagulation necrosis. MWA and CTP were prospectively performed in five healthy pigs. After the procedure, the pigs were euthanized, and the livers explanted. Orthogonal histological slices of the ablations were stained with a vital stain, digitalized and the necrotic core was segmented. CTP maps were calculated using a dual-input deconvolution algorithm. The segmented necrotic zones were overlaid on the DICOM images to calculate the accuracy of depiction by CECT/CTP compared to the histological reference standard. A receiver operating characteristic analysis was performed to determine the agreement/true positive rate and disagreement/false discovery rate between CECT/CTP and histology. Standard CECT showed a true positive rate of 81% and a false discovery rate of 52% for display of the coagulation necrosis. Using CTP, delineation of the coagulation necrosis could be improved significantly through the display of hepatic blood volume and hepatic arterial blood flow (p < 0.001). The ratios of true positive rate/false discovery rate were 89%/25% and 90%/50% respectively. Other parameter maps showed an inferior performance compared to CECT

Innovative Learning and Teaching: Experiments Across the Disciplines

The authors collected in Innovations in Learning and Teaching are faculty and instructors from various University of Minnesota campuses, each part of a team that successfully completed university-funded grant projects with teaching and technology consultants. Here, several faculty extend the conversation through scholarship of learning and teaching articles. Readers, including future faculty, as well as current instructors, faculty, administrators, regents and legislators, will benefit from the authors’ attention to learners, complex learning, practicable pedagogy, and curricular experimentation.University of Minnesota Center for Educational Innovatio

Does Bitcoin hedge commodity uncertainty?

This paper examines the connectedness between Bitcoin and commodity volatilities, including oil, wheat, and corn, during the period Oct. 2013–Jun. 2018, using time- and frequency-domain frameworks. The time-domain framework’s results show that the connectedness is 23.49%, indicating a low level of connection between Bitcoin and the commodity volatilities. Bitcoin contributes only 2.55% to the connectedness, while the wheat volatility index accounts for 12.51% of the total connectedness. The frequency connectedness shows that Bitcoin’s contribution to the total connectedness increases from high-frequency to low-frequency bands, and the total connectedness reaches up to 22.47%. It also indicates that Bitcoin is the spillover transmitter to the wheat volatility, while being the spillover receiver from the oil and corn volatilities. The findings suggest that Bitcoin could be a hedger for commodity volatilities

Conservation of soil organic carbon, biodiversity and the provision of other ecosystem services along climatic gradients in West Africa

Terrestrial carbon resources are major drivers of development in West Africa. The distribution of these resources co-varies with ecosystem type and rainfall along a strong Northeast-Southwest climatic gradient. Soil organic carbon, a strong indicator of soil quality, has been severely depleted in some areas by human activities, which leads to issues of soil erosion and desertification, but this trend can be altered with appropriate management. There is significant potential to enhance existing soil carbon stores in West Africa, with benefits at the global and local scale, for atmospheric CO2 mitigation as well as supporting and provisioning ecosystem services. Three key factors impacting carbon stocks are addressed in this review: climate, biotic factors, and human activities. Climate risks must be considered in a framework of global change, especially in West Africa, where landscape managers have few resources available to adapt to climatic perturbations. Among biotic factors, biodiversity conservation paired with carbon conservation may provide a pathway to sustainable development, and biodiversity conservation is also a global priority with local benefits for ecosystem resilience, biomass productivity, and provisioning services such as foodstuffs. Finally, human management has largely been responsible for reduced carbon stocks, but this trend can be reversed through the implementation of appropriate carbon conservation strategies in the agricultural sector, as shown by multiple studies. Owing to the strong regional climatic gradient, country-level initiatives will need to consider carbon sequestration approaches for multiple ecosystem types. Given the diversity of environments, global policies must be adapted and strategies developed at the national or sub-national levels to improve carbon storage above and belowground. Initiatives of this sort must act locally at farmer scale, and focus on ecosystem services rather than on carbon sequestration solely

Getting More From Your Maze: Examining Differences in Distractors

The present study examined the technical adequacy of maze-selection tasks constructed in 2 different ways: typical versus novel. We selected distractors for each measure systematically based on rules related to the content of the passage and the part of speech of the correct choice. Participants included 262 middle school students who were randomly assigned to 1 of the 2 maze formats. Scoring of the maze included both correct and correct-minus-incorrect scores. Students completed 3 criterion-reading tests: the Scholastic Reading Inventory, the AIMSweb R-Maze, and a high-stakes state assessment (the Missouri Assessment Program). Alternate-forms reliability was similar across maze formats; however, with regard to scoring procedure, reliability coefficients were consistently higher for correct than for correct-minus-incorrect scores. Validity coefficients were also similar across format with 1 exception: The coefficients for typical maze scores were stronger when compared with the Missouri Assessment Program scores than the coefficients for novel maze scores

Combining data-driven and domain knowledge components in an intelligent assistant to build personalized menus

In this paper, some new components that have been integrated in the Diet4You system for the generation of nutritional plans are introduced. Negative user preferences have been modelled and introduced in the system. Furthermore, the cultural eating styles originated from the location where the user lives have been taken into account dividing the original menu plan in sub-plans. Each sub-plan is in charge to optimize one of the meals of one day in the personal menu of the user. The main latent reasoning mechanism used is case-based reasoning, which reuses previous menu configurations according to the nutritional plan and the corresponding hard constraints and the user preferences to meet a personalized recommendation menu for a given user. It uses the cognitive analogical reasoning technique in addition to ontologies, nutritional databases and expert knowledge. The preliminary results with some examples of application to test the new contextual components have been very satisfactory according to the evaluation of the experts.This work has been partially supported by the project Diet4You (TIN2014-60557-R), the Spanish Thematic Network MAPAS [TIN2017-90567-REDT (MINECO/FEDER EU)], and the Consolidated Research Group Grant from AGAUR (Generalitat de Catalunya) IDEAI-UPC (AGAUR SGR2017-574).Peer ReviewedPostprint (author's final draft

Perivascular vital cells in the ablation center after multibipolar radiofrequency ablation in an in vivo porcine model

Multibipolar radiofrequency ablation (RFA) is an advanced ablation technique for early stage hepatocellular carcinoma and liver metastases. Vessel cooling in multibipolar RFA has not been systematically investigated. The objective of this study was to evaluate the presence of perivascular vital cells within the ablation zone after multibipolar RFA. Multibipolar RFA were performed in domestic pigs in vivo. Three internally cooled bipolar RFA applicators were used simultaneously. Three experimental settings were planned: (1) inter-applicator-distance: 15 mm; (2) inter-applicator-distance: 20 mm; (3) inter-applicator-distance: 20 mm with hepatic inflow occlusion (Pringle maneuver). A vitality staining was used to analyze liver cell vitality around all vessels in the ablation center with a diameter>0.5 mm histologically. 771 vessels were identified. No vital tissue was seen around 423 out of 429 vessels (98.6%) situated within the central white zone. Vital cells could be observed around major hepatic vessels situated adjacent to the ablation center. Vessel diameter (>3.0 mm; p<0.05) and low vessel-to-ablation-center distance (<0.2 mm; p<0.05) were identified as risk factors for incomplete ablation adjacent to hepatic vessels. The vast majority of vessels, which were localized in the clinically relevant white zone, showed no vital perivascular cells, regardless of vessel diameter and vessel type. However, there was a risk of incomplete ablation around major hepatic vessels situated directly within the ablation center. A Pringle maneuver could avoid incomplete ablations