Experimental Studies of Cylinder Group State During Motoring

AbstractThe paper describes a method for diagnosing the cylinder-piston group of internal combustion engines (ICE). The method is based on analyzing the results of measuring the dynamic compression during crankshaft motoring. The position of the maximum pressure in the combustion chamber, its magnitude and phase parameters give a complete picture of the technical state of the engine cylinder group. Measured parameters of the pressure signal were compared to instrumental measurements of air leakage in the cylinder-piston group as well as to the compression values. The developed method allows to combine all the positive aspects of existing and proposed methods and to solve the long-standing problem of improving the accuracy of estimating the technical state of ICE units and mechanisms. cylinders, rings, pistons, valves, displacement of phases timing. Experimental results are presented as graphs showing the inter-dependency of parameters of the processes under consideration

Densification, morphological and transport properties of functional La1–xBaxYbO3– δ ceramic materials

The effective operation of protonic ceramic electrochemical cells requires the design of electrolytes having not only high ionic conductivity, but also excellent stability with respect to carbonisation. In the present work, the La-based oxides (La1–xBaxYbO3–δ, 0.03 ≤ x ≤ 0.10) are proposed as a possible alternative to the convenient Ba(Ce,Zr)O3-based electrolytes due to their high chemical stability. It was discovered that Ba-doping results in a deterioration of sintering behaviour; as a result, the relative density decreases and open porosity appears (for x = 0.10). A thorough analysis of transport properties by means of AC and DC measurement techniques enables a selection of the La0.97Ba0.03YbO3–δ sample, which demonstrates the highest conductivity compared with those samples where x = 0.5 and 0.10. Due to its excellent densification behaviour, stability and ionic conductivity, La0.97Ba0.03YbO3–δ can be considered as a promising proton-conducting electrolyte in the La-based family. © 2019 Elsevier Lt

Prognostic value of leukocyte indices in acute severe pancreatitis

The article analyzed the results of laboratory blood tests obtained in patients on the day of entry into the body and calculated for various leukocyte indices in patients with acute severe pancreatitis. The study based on the case reports of the MAI “City Clinical Hospital” No. 40 of Yekaterinburg in the period 2015-2020. The study aim is to identify the informative value of leukocyte indicators in relation to predicting the severity of acute pancreatitis and mortality. Some leukocyte indices have sufficient information in predicting the severity, course of acute pancreatitis and mortality, taking into account the incidence.В статье были проанализированы результаты лабораторных исследований крови, полученных у пациентов в день поступления в приемный покой и рассчитаны различные лейкоцитарные индексы у пациентов с острым тяжелым панкреатитом. Исследование проведено по материалам историй болезни МАУ «Городская клиническая больница» №40 г. Екатеринбурга в период 2015-2020 гг. Проведенное исследование было направлено на выявление информативности лейкоцитарных индексов в отношении прогнозирования тяжести течения острого панкреатита и летальности. Некоторые лейкоцитарные индексы обладают достаточной информативностью в прогнозировании тяжести течения острого панкреатита и летальности, связанной с данным заболеванием

Rotavirus NSP1 Inhibits NFκB Activation by Inducing Proteasome-Dependent Degradation of β-TrCP: A Novel Mechanism of IFN Antagonism

Mechanisms by which viruses counter innate host defense responses generally involve inhibition of one or more components of the interferon (IFN) system. Multiple steps in the induction and amplification of IFN signaling are targeted for inhibition by viral proteins, and many of the IFN antagonists have direct or indirect effects on activation of latent cytoplasmic transcription factors. Rotavirus nonstructural protein NSP1 blocks transcription of type I IFNα/β by inducing proteasome-dependent degradation of IFN-regulatory factors 3 (IRF3), IRF5, and IRF7. In this study, we show that rotavirus NSP1 also inhibits activation of NFκB and does so by a novel mechanism. Proteasome-mediated degradation of inhibitor of κB (IκBα) is required for NFκB activation. Phosphorylated IκBα is a substrate for polyubiquitination by a multisubunit E3 ubiquitin ligase complex, Skp1/Cul1/F-box, in which the F-box substrate recognition protein is β-transducin repeat containing protein (β-TrCP). The data presented show that phosphorylated IκBα is stable in rotavirus-infected cells because infection induces proteasome-dependent degradation of β-TrCP. NSP1 expressed in isolation in transiently transfected cells is sufficient to induce this effect. Targeted degradation of an F-box protein of an E3 ligase complex with a prominent role in modulation of innate immune signaling and cell proliferation pathways is a unique mechanism of IFN antagonism and defines a second strategy of immune evasion used by rotaviruses

Concentration profiles of Zn ions implanted with 60 keV for nanoparticle formation in silica glass

Surface recession due to sputtering under low-energy and high-fluence heavy-ion implantation makes shallower and broader depth profile of implanted ions than those calculated by conventional ion-range simulation-codes such as SRIM. Depth profiles of Zn atoms in silica glasses NOD implanted with Zn+ ions of 60 keV up to 1.0 X 10(17) ions/cm(2) were evaluated using both experimental methods as Rutherford backscattering spectrometry (RBS), sputtering depth-profiling by X-ray photoelectron spectroscopy (XPS), and an advanced numerical simulation code TRIDYN, which includes the sputtering loss effects. The TRIDYN code predicts the shallowing of the projectile range from similar to 46 to similar to 27 nm with increasing the fluence up to 1 X 10(17) ions/cm(2), and very high-concentration (similar to 20 at%) of Zn atoms close to the surface. However, RBS and XPS results exclude such high concentration close to the surface. These results suggest remarkable redistribution of Zn atoms from the nearer surface to the deeper region during the implantation. In fact, Zn-atom concentration near the surface and that near the projectile range are, respectively, lower and higher than those by the SRIM code predictions. (c) 2005 Elsevier Ltd. All rights reserved

Experimental verification of PIPS-detector dosimeters for measurements in mixed radiation fields

The paper describes the features of operation and testing of Russian dosimeters made on the basis of PIPS detectors for assessing radiation environment in space flights and for mixed radiation fields. Preliminary results of testing with high-energy protons and heavy ions are considered. Experimental results were verified by German M-42 silicone dosimeter. M-42 dosimeter model has been already proven credible for aviation and space flight dosimetry