806 research outputs found
A Chandra detection of diffuse hard X-ray emission associated with the lobes of the radio galaxy 3C 452
An 80 ksec Chandra ACIS observation of the radio galaxy 3C 452 is reported. A
diffuse X-ray emission associated with the lobes has been detected with high
statistical significance, together with the X-ray nucleus of the host galaxy.
The 0.5--5 keV ACIS spectrum of the diffuse emission is described by a
two-component model, consisting of a soft thermal plasma emission from the host
galaxy halo and a hard non-thermal power-law component. The hard component is
ascribed to the inverse Comptonization of cosmic microwave background photons
by the synchrotron emitting electrons in the lobes, because its spectral energy
index, 0.68+-0.28, is consistent with the radio synchrotron index, 0.78. These
results reveal a significant electron dominance in the lobes. The electrons are
inferred to have a relatively uniform distribution, while the magnetic field is
compressed toward the lobe periphery.Comment: 4 figures, 2 tables, Accepted by ApJL (to appear in the December 1
issue
The tumor-educated-macrophage increase of malignancy of human pancreatic cancer is prevented by zoledronic acid.
We previously defined macrophages harvested from the peritoneal cavity of nude mice with subcutaneous human pancreatic tumors as "tumor-educated-macrophages" (Edu) and macrophages harvested from mice without tumors as "naïve-macrophages" (Naïve), and demonstrated that Edu-macrophages promoted tumor growth and metastasis. In this study, Edu- and Naïve-macrophages were compared for their ability to enhance pancreatic cancer malignancy at the cellular level in vitro and in vivo. The inhibitory efficacy of Zoledronic acid (ZA) on Edu-macrophage-enhanced metastasis was also determined. XPA1 human pancreatic cancer cells in Gelfoam co-cultured with Edu-macrophages proliferated to a greater extent compared to XPA1 cells cultured with Naïve-macrophages (P = 0.014). XPA1 cells exposed to conditioned medium harvested from Edu culture significantly increased proliferation (P = 0.016) and had more migration stimulation capability (P<0.001) compared to cultured cancer cells treated with the conditioned medium from Naïve. The mitotic index of the XPA1 cells, expressing GFP in the nucleus and RFP in the cytoplasm, significantly increased in vivo in the presence of Edu- compared to Naïve-macrophages (P = 0.001). Zoledronic acid (ZA) killed both Edu and Naïve in vitro. Edu promoted tumor growth and metastasis in an orthotopic mouse model of the XPA1 human pancreatic cancer cell line. ZA reduced primary tumor growth (P = 0.006) and prevented metastasis (P = 0.025) promoted by Edu-macrophages. These results indicate that ZA inhibits enhanced primary tumor growth and metastasis of human pancreatic cancer induced by Edu-macrophages
Nature of Electron Order in LaSrMnO
Synchrotron x-ray scattering measurements of the low-temperature structure of
the single-layer manganese oxide LaSrMnO, over the doping
range , indicate the existence of three distinct regions:
a disordered phase (), a charge-ordered phase (), and a
mixed phase (, the modulation vector associated
with the charge order is incommensurate with the lattice and depends linearly
on the concentration of electrons. The primary superlattice reflections
are strongly suppressed along the modulation direction and the higher harmonics
are weak, implying the existence of a largely transverse and nearly sinusoidal
structural distortion, consistent with a charge density wave of the
electrons.Comment: 4 pages, 4 figure
Charge melting and polaron collapse in
X-ray and neutron scattering measurements directly demonstrate the existence
of polarons in the paramagnetic phase of optimally-doped colossal
magnetoresistive oxides. The polarons exhibit short-range correlations that
grow with decreasing temperature, but disappear abruptly at the ferromagnetic
transition because of the sudden charge delocalization. The "melting" of the
charge ordering as we cool through occurs with the collapse of the
quasi-static polaron scattering, and provides important new insights into the
relation of polarons to colossal magnetoresistance.Comment: 4 pages (RevTex), 3 postscript-formatted figures (Figs. 1 and 2 are
color figures
Dopant-dependent impact of Mn-site doping on the critical-state manganites: R0.6Sr0.4MnO3 (R=La, Nd, Sm, and Gd)
Versatile features of impurity doping effects on perovskite manganites,
SrMnO, have been investigated with varying the doing
species as well as the -dependent one-electron bandwidth. In
ferromagnetic-metallic manganites (=La, Nd, and Sm), a few percent of Fe
substitution dramatically decreases the ferromagnetic transition temperature,
leading to a spin glass insulating state with short-range charge-orbital
correlation. For each species, the phase diagram as a function of Fe
concentration is closely similar to that for SrMnO
obtained by decreasing the ionic radius of site, indicating that Fe doping
in the phase-competing region weakens the ferromagnetic double-exchange
interaction, relatively to the charge-orbital ordering instability. We have
also found a contrastive impact of Cr (or Ru) doping on a spin-glass insulating
manganite (=Gd). There, the impurity-induced ferromagnetic magnetization is
observed at low temperatures as a consequence of the collapse of the inherent
short-range charge-orbital ordering, while Fe doping plays only a minor role.
The observed opposite nature of impurity doping may be attributed to the
difference in magnitude of the antiferromagnetic interaction between the doped
ions.Comment: 7 pages, 6 figure
On-orbit Operations and Offline Data Processing of CALET onboard the ISS
The CALorimetric Electron Telescope (CALET), launched for installation on the
International Space Station (ISS) in August, 2015, has been accumulating
scientific data since October, 2015. CALET is intended to perform long-duration
observations of high-energy cosmic rays onboard the ISS. CALET directly
measures the cosmic-ray electron spectrum in the energy range of 1 GeV to 20
TeV with a 2% energy resolution above 30 GeV. In addition, the instrument can
measure the spectrum of gamma rays well into the TeV range, and the spectra of
protons and nuclei up to a PeV.
In order to operate the CALET onboard ISS, JAXA Ground Support Equipment
(JAXA-GSE) and the Waseda CALET Operations Center (WCOC) have been established.
Scientific operations using CALET are planned at WCOC, taking into account
orbital variations of geomagnetic rigidity cutoff. Scheduled command sequences
are used to control the CALET observation modes on orbit. Calibration data
acquisition by, for example, recording pedestal and penetrating particle
events, a low-energy electron trigger mode operating at high geomagnetic
latitude, a low-energy gamma-ray trigger mode operating at low geomagnetic
latitude, and an ultra heavy trigger mode, are scheduled around the ISS orbit
while maintaining maximum exposure to high-energy electrons and other
high-energy shower events by always having the high-energy trigger mode active.
The WCOC also prepares and distributes CALET flight data to collaborators in
Italy and the United States.
As of August 31, 2017, the total observation time is 689 days with a live
time fraction of the total time of approximately 84%. Nearly 450 million events
are collected with a high-energy (E>10 GeV) trigger. By combining all operation
modes with the excellent-quality on-orbit data collected thus far, it is
expected that a five-year observation period will provide a wealth of new and
interesting results.Comment: 11 pages, 7 figures, published online 27 February 201
Search for GeV Gamma-ray Counterparts of Gravitational Wave Events by CALET
We present results on searches for gamma-ray counterparts of the LIGO/Virgo
gravitational-wave events using CALorimetric Electron Telescope ({\sl CALET})
observations. The main instrument of {\sl CALET}, CALorimeter (CAL), observes
gamma-rays from GeV up to 10 TeV with a field of view of nearly 2 sr.
In addition, the {\sl CALET} gamma-ray burst monitor (CGBM) views 3 sr
and sr of the sky in the 7 keV -- 1 MeV and the 40 keV -- 20 MeV
bands, respectively, by using two different crystal scintillators. The {\sl
CALET} observations on the International Space Station started in October 2015,
and here we report analyses of events associated with the following
gravitational wave events: GW151226, GW170104, GW170608, GW170814 and GW170817.
Although only upper limits on gamma-ray emission are obtained, they correspond
to a luminosity of erg s in the GeV energy band
depending on the distance and the assumed time duration of each event, which is
approximately the order of luminosity of typical short gamma-ray bursts. This
implies there will be a favorable opportunity to detect high-energy gamma-ray
emission in further observations if additional gravitational wave events with
favorable geometry will occur within our field-of-view. We also show the
sensitivity of {\sl CALET} for gamma-ray transient events which is the order of
~erg\,cm\,s for an observation of 100~s duration.Comment: 12 pages, 8 figures, 1 table. Accepted for publication in
Astrophysical Journa
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