675 research outputs found
Certain Properties of Fractional Calculus Operators Associated with Generalized Mittag-Leffler Function
Mathematics Subject Classification: 26A33, 33E12, 33C20.It has been shown that the fractional integration and differentiation operators transform
such functions with power multipliers into the functions of the same form.
Some of the results given earlier by Kilbas and Saigo follow as special cases
Phase Diagram of Pressure-Induced Superconductivity in EuFe2As2 Probed by High-Pressure Resistivity up to 3.2 GPa
We have constructed a pressuretemperature () phase diagram of
-induced superconductivity in EuFeAs single crystals, via
resistivity () measurements up to 3.2 GPa. As hydrostatic pressure is
applied, an antiferromagnetic (AF) transition attributed to the FeAs layers at
shifts to lower temperatures, and the corresponding resistive
anomaly becomes undetectable for 2.5 GPa. This suggests that the
critical pressure where becomes zero is about 2.5
GPa. We have found that the AF order of the Eu moments survives up to
3.2 GPa without significant changes in the AF ordering temperature
. The superconducting (SC) ground state with a sharp transition
to zero resistivity at 30 K, indicative of bulk
superconductivity, emerges in a pressure range from 2.5
GPa to 3.0 GPa. At pressures close to but outside the SC phase, the
curve shows a partial SC transition (i.e., zero resistivity is not
attained) followed by a reentrant-like hump at approximately
with decreasing temperature. When nonhydrostatic pressure with a uniaxial-like
strain component is applied using a solid pressure medium, the partial
superconductivity is continuously observed in a wide pressure range from 1.1
GPa to 3.2 GPa.Comment: 7 pages, 6 figures, accepted for publication in Physical Review B,
selected as "Editors' Suggestion
Developmental Curiosity and Social Interaction in Virtual Agents
Infants explore their complex physical and social environment in an organized
way. To gain insight into what intrinsic motivations may help structure this
exploration, we create a virtual infant agent and place it in a
developmentally-inspired 3D environment with no external rewards. The
environment has a virtual caregiver agent with the capability to interact
contingently with the infant agent in ways that resemble play. We test
intrinsic reward functions that are similar to motivations that have been
proposed to drive exploration in humans: surprise, uncertainty, novelty, and
learning progress. These generic reward functions lead the infant agent to
explore its environment and discover the contingencies that are embedded into
the caregiver agent. The reward functions that are proxies for novelty and
uncertainty are the most successful in generating diverse experiences and
activating the environment contingencies. We also find that learning a world
model in the presence of an attentive caregiver helps the infant agent learn
how to predict scenarios with challenging social and physical dynamics. Taken
together, our findings provide insight into how curiosity-like intrinsic
rewards and contingent social interaction lead to dynamic social behavior and
the creation of a robust predictive world model.Comment: 6 pages, 5 figures, 2 tables; accepted to CogSci 2023 with full paper
publication in the proceeding
Eye contrast polarity is critical for face recognition by infants
Just as faces share the same basic arrangement of features, with two eyes above a nose above a mouth, human eyes all share the same basic contrast polarity relations, with a sclera lighter than an iris and a pupil, and this is unique among primates. The current study examined whether this bright-dark relationship of sclera to iris plays a critical role in face recognition from early in development. Specifically, we tested face discrimination in 7- and 8-month-old infants while independently manipulating the contrast polarity of the eye region and of the rest of the face. This gave four face contrast polarity conditions: fully positive condition, fully negative condition, positive face with negated eyes ( negative eyes ) condition, and negated face with positive eyes ( positive eyes ) condition. In a familiarization and novelty preference procedure, we found that 7- and 8-month-olds could discriminate between faces only when the contrast polarity of the eyes was preserved (positive) and that this did not depend on the contrast polarity of the rest of the face. This demonstrates the critical role of eye contrast polarity for face recognition in 7- and 8-month-olds and is consistent with previous findings for adults
First-principles study of electron transport through cages
Electron transport properties of C molecules suspended between gold
electrodes are investigated using first-principles calculations. Our study
reveals that the conductances are quite sensitive to the number of C
molecules between electrodes: the conductances of C monomers are near 1
G, while those of dimers are markedly smaller, since incident electrons
easily pass the C molecules and are predominantly scattered at the
C-C junctions. Moreover, we find both channel currents locally
circulating the outermost carbon atoms.Comment: 8 pages and 3 figure
Pengaruh Kohesivitas dan Kepuasan Kerja Terhadap Kinerja Tenaga Kependidikan di Institut Pertanian Bogor
ABSTRACTIt is generally believed that there is a positive relationship among the following three variables, which are cohesiveness, job satisfaction, and job performance. Good job performance of a group of workers needs good coorperation among the group members. Good cooperation can be viewed as the outcome of group cohesiveness. In addition, good job performance needs good job satisfaction. Furthermore, it is also commonly believed that group cohesiveness is positively related with job satisfaction. The objective of this study is to empirically test the phenomenon by conducting a survey on 102 respondents who are administrative staff in Bogor Agricultural University. A quantitative model namely Structural Equation Model (SEM) was utilized. It is concluded that cohesiveness positively effects job satisfaction as well as well as job performance. However, it is found that there is no statistically significant effect of job satisfaction on job performance.ABSTRAKUmumnya dipercayai bahwa ada hubungan positif antara tiga variabel berikut, yakni kohesivitas kelompok, kepuasan kerja, dan kinerja. Kinerja kelompok membutuhkan kerja sama di antara para anggota kelompok. Kerja sama yang baik dapat dipandang sebagai buah dari kohesivitas. Tambahan pula, kinerja yang baik membutuhkan kepuasan kerja yang baik pula. Lebih lanjut, lazimnya dipercayai bahwa kohesivitas berhubungan dengan kepuasan kerja. Studi ini secara empiris menguji fenomena tersebut dengan menggunakan survei terhadap 102 responden yang adalah tenaga kependidikan di Institut Pertanian Bogor. Model kuantitatif menggunakan Structural Equation Model (SEM). Ditunjukkan bahwa kohesivitas berpengaruh positif terhadap kepuasan kerja maupun terhadap kinerja. Namun ditemukan bahwa tidak ada pengaruh yang signifikan dari kepuasan kerja pada kinerja
Effect of High Fat Loading in Dahl Salt-Sensitive Rats
Salt sensitivity of blood pressure (BP) is speculated to be a characteristic in obesity-induced hypertension. To elucidate the influence of obesity on salt-sensitive hypertension, we examined the effect of fat loading on BP, renal damage, and their progression induced by salt excess in Dahl salt-sensitive (S) rats. High fat (HF: 45% fat diet: 8 weeks) diet increased BP with greater weight gain and visceral fat accumulation than low fat (10% fat) diet. In HF-fed rats, plasma glucose, plasma insulin, and urinary catecholamine increased, and urinary protein tended to be elevated. Moreover, excessive salt (8% salt diet: 8 weeks)-induced hypertension and proteinuria was accelerated in HF-fed rats. Therefore, fat loading increased BP in Dahl S rats possibly through insulin-resistance and sympathetic excitation. Moreover, fat loading accelerated salt-induced BP elevation and renal damage, suggesting excessive intake of both fat and salt, such as a civilized diet, exert the synergic harmful effects
Title page Involvement of Human Organic Cation Transporter 1 (OCT1) in the Hepatic Uptake of YM155 Monobromide, 1-(2-Methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium Bromide, a Novel, Small Molecule Survivi
Abstract YM155 monobromide, 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide, which is a hydrophilic and cationic compound, exhibits anti-tumor activity in experimental human hormone refractory prostate carcinoma models. Urinary excretion was 18.3% to 28.6% of the dose in the clinical phase I study, and non-renal elimination may be explained by the biliary excretion of YM155 in its unchanged form. As the penetration through the sinusoidal membrane of the hepatocytes is the first step and an important part of biliary excretion, we evaluated the uptake o
A new case of GABA transaminase deficiency facilitated by proton MR spectroscopy
BACKGROUND: Deficiency of 4-aminobutyrate aminotransferase (GABA-T) is a rare disorder of GABA catabolism, with only a single sibship reported. We report on a third case, a Japanese female infant with severe psychomotor retardation and recurrent episodic lethargy with intractable seizures, with the diagnosis facilitated by proton magnetic resonance (MR) spectroscopy ((1)H-MRS). METHODS: Neuroimaging was performed at the first episode of lethargy. For (1)H-MRS, locations were placed in the semioval center and the basal ganglia. Quantification of metabolite concentrations were derived using the LCModel. We confirmed the diagnosis subsequently by enzyme and molecular studies, which involved direct DNA sequence analysis and the development of a novel multiplex ligation-dependent probe amplification test. RESULTS: (1)H-MRS analysis revealed an elevated GABA concentration in the basal ganglia (2.9 mmol/l). Based on the results of quantitative (1)H-MRS and clinical findings, GABA-T deficiency was suspected and confirmed in cultured lymphoblasts. Molecular studies of the GABA-T gene revealed compound heterozygosity for a deletion of one exon and a missense mutation, 275G>A, which was not detected in 210 control chromosomes. CONCLUSIONS: Our results suggest that excessive prenatal GABA exposure in the central nervous system (CNS) was responsible for the clinical manifestations of GABA transaminase deficiency. Our findings suggest the dual nature of GABA as an excitatory molecule early in life, followed by a functional switch to an inhibitory species later in development. Furthermore, quantitative (1)H-MRS appears to be a useful, noninvasive tool for detecting inborn errors of GABA metabolism in the CNS
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