5,750 research outputs found
Special studies of AROD system concepts and designs
Signal to noise ratios in airborne range and orbit determination system, and carrier and range loop performance analyse
Cross section normalization in proton-proton collisions at = 2.76 TeV and 7 TeV, with ALICE at LHC
Measurements of the cross sections of the reference processes seen by the
ALICE trigger system were obtained based on beam properties measured from van
der Meer scans. The measurements are essential for absolute cross section
determinations of physics processes.
The paper focuses on instrumental and technical aspects of detectors and
accelerators, including a description of the extraction of beam properties from
the van der Meer scan. As a result, cross sections of reference processes seen
by the ALICE trigger system are given for proton-proton collisions at two
energies; =2.76 TeV and 7 TeV, together with systematic uncertainties
originating from beam intensity measurements and other detector effects.
Consistency checks were performed by comparing to data from other experiments
in LHC.Comment: Quark Matter 2011 Conference Proceedings, 4 pages, 2 figure
Титульні сторінки
Influenza virus and vesicular stomatitis virus (VSV) obtain their lipid envelope by budding through the plasma membrane of infected cells. When monolayers of Madin-Darby canine kidney (MDCK) cells, a polarized epithelial cell line, are infected with fowl plague virus (FPV), an avian influenza virus, or with VSV, new FPV buds through the apical plasma membrane whereas VSV progeny is formed by budding through the basolateral plasma membrane. FPV and VSV were isolated from MDCK host cells prelabeled with [32P]orthophosphate and their phospholipid compositions were compared. Infection was carried out at 31 degrees C to delay cytopathic effects of the virus infection, which lead to depolarization of the cell surface. 32P-labeled FPV was isolated from the culture medium, whereas 32P-labeled VSV was released from below the cell monolayer by scraping the cells from the culture dish 8 h after infection. At this time little VSV was found in the culture medium, indicating that the cells were still polarized. The phospholipid composition of the two viruses was distinctly different. FPV was enriched in phosphatidylethanolamine and phosphatidylserine and VSV in phosphatidylcholine, sphingomyelin, and phosphatidylinositol. When MDCK cells were trypsinized after infection and replated, non-infected control cells attached to reform a confluent monolayer within 4 h, whereas infected cells remained in suspension. FPV and VSV could be isolated from the cells in suspension and under these conditions the phospholipid composition of the two viruses was very similar. We conclude that the two viruses obtain their lipids from the plasma membrane in the same way and that the different phospholipid compositions of the viruses from polarized cells reflect differences in the phospholipid composition of the two plasma membrane domains
FUZZY LOGIC BASED ZSI USING PMSG FOR WECS
In recent decades various renewable energy resources have attracted a lot of attention because they are pollution-free and inexhaustible. Wind power is the conversion of wind energy into a useful form of energy, such as using wind turbines to make electricity, wind mills for mechanical power, wind pumps for pumping water or drainage, or sails to propel ships
Molecular Structure and Diversity of PBAN/pyrokinin Family Peptides in Ants
Neuropeptides are the largest group of insect hormones. They are produced in the central and peripheral nervous systems and affect insect development, reproduction, feeding, and behavior. A variety of neuropeptide families have been identified in insects. One of these families is the PBAN/pyrokinin family defined by a common FXPRLamide or similar amino acid fragment at the C-terminal end. These peptides, found in all insects studied thus far, have been conserved throughout evolution. The most well studied physiological function is regulation of moth sex pheromone biosynthesis through the pheromone biosynthesis activating neuropeptide (PBAN), although several developmental functions have also been reported. Over the past years we have extended knowledge of the PBAN/pyrokinin family of peptides to ants, focusing mainly on the fire ant, Solenopsis invicta. The fire ant is one of the most studied social insects and over the last 60 years a great deal has been learned about many aspects of this ant, including the behaviors and chemistry of pheromone communication. However, virtually nothing is known about the regulation of these pheromone systems. Recently, we demonstrated the presence of PBAN/pyrokinin immunoreactive neurons in the fire ant, and identified and characterized PBAN and additional neuropeptides. We have mapped the fire ant PBAN gene structure and determined the tissue expression level in the central nervous system of the ant. We review here our research to date on the molecular structure and diversity of ant PBAN/pyrokinin peptides in preparation for determining the function of the neuropeptides in ants and other social insects
Hysteretic clustering in granular gas
Granular material is vibro-fluidized in N=2 and N=3 connected compartments,
respectively. For sufficiently strong shaking the granular gas is
equi-partitioned, but if the shaking intensity is lowered, the gas clusters in
one compartment. The phase transition towards the clustered state is of 2nd
order for N=2 and of 1st order for N=3. In particular, the latter is
hysteretic. The experimental findings are accounted for within a dynamical
model that exactly has the above properties
Condensation phase transitions of symmetric conserved-mass aggregation model on complex networks
We investigate condensation phase transitions of symmetric conserved-mass
aggregation (SCA) model on random networks (RNs) and scale-free networks (SFNs)
with degree distribution . In SCA model, masses diffuse
with unite rate, and unit mass chips off from mass with rate . The
dynamics conserves total mass density . In the steady state, on RNs and
SFNs with for , we numerically show that SCA
model undergoes the same type condensation transitions as those on regular
lattices. However the critical line depends on network
structures. On SFNs with , the fluid phase of exponential mass
distribution completely disappears and no phase transitions occurs. Instead,
the condensation with exponentially decaying background mass distribution
always takes place for any non-zero density. For the existence of the condensed
phase for at the zero density limit, we investigate one
lamb-lion problem on RNs and SFNs. We numerically show that a lamb survives
indefinitely with finite survival probability on RNs and SFNs with ,
and dies out exponentially on SFNs with . The finite life time
of a lamb on SFNs with ensures the existence of the
condensation at the zero density limit on SFNs with at which
direct numerical simulations are practically impossible. At ,
we numerically confirm that complete condensation takes place for any on RNs. Together with the recent study on SFNs, the complete condensation
always occurs on both RNs and SFNs in zero range process with constant hopping
rate.Comment: 6 pages, 6 figure
Sudden Collapse of a Granular Cluster
Single clusters in a vibro-fluidized granular gas in N connected compartments
become unstable at strong shaking. They are experimentally shown to collapse
very abruptly. The observed cluster lifetime (as a function of the driving
intensity) is analytically calculated within a flux model, making use of the
self-similarity of the process. After collapse, the cluster diffuses out into
the uniform distribution in a self-similar way, with an anomalous diffusion
exponent 1/3.Comment: 4 pages, 4 figures. Figure quality has been reduced in order to
decrease file-siz
Reducing the anticholinergic and sedative load in older patients on polypharmacy by pharmacist-led medication review: A randomised controlled trial
© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. Objective To evaluate if a pharmacist-led medication review is effective at reducing the anticholinergic/sedative load, as measured by the Drug Burden Index (DBI). Design Randomised controlled single blind trial. Setting 15 community pharmacies in the Northern Netherlands. Participants 157 community-dwelling patients aged ≥65 years who used ≥5 medicines for ≥3 months, including at least one psycholeptic/psychoanaleptic medication and who had a DBI≥1. Intervention A medication review by the community pharmacist in collaboration with the patient's general practitioner and patient. Primary and secondary outcomes measures The primary outcome was the proportion of patients whose DBI decreased by at least 0.5. Secondary outcomes were the presence of anticholinergic/sedative side effects, falls, cognitive function, activities of daily living, quality of life, hospital admission and mortality. Data were collected at baseline and 3 months follow-up. Results Mean participant age was 75.7 (SD, 6.9) years in the intervention arm and 76.6 (SD, 6.7) years in the control arm, the majority were female (respectively 69.3% and 72.0%). Logistic regression analysis showed no difference in the proportion of patients with a≥0.5 decrease in DBI between intervention arm (17.3%) and control arm (15.9%), (OR 1.04, CI 0.47 to 2.64, p=0.927). Intervention patients scored higher on the Digit Symbol Substitution Test, measure of cognitive function (OR 2.02, CI 1.11 to 3.67, p=0.021) and reported fewer sedative side effects (OR 0.61, CI 0.40 to 0.94, p=0.024) at follow-up. No significant difference was found for other secondary outcomes. Conclusions Pharmacist-led medication review as currently performed in the Netherlands was not effective in reducing the anticholinergic/sedative load, measured with the DBI, within the time frame of 3 months. Preventive strategies, signalling a rising load and taking action before chronic use of anticholinergic/sedative medication is established may be more successful. Trial registration number NCT02317666
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