Separating Obligations of Subjects and Handlers for More Flexible Event Type Verification

International audienceImplicit invocation languages, like aspect-oriented languages, automate the Observer pattern, which decouples subjects (base code) from handlers (advice), and then compound them together in the final system. For such languages, event types have been proposed as a way of further decoupling subjects from handlers. In Ptolemy, subjects explicitly announce events at certain program points, and pass the announced piece of code to the handlers for its eventual execution. This implies a mutual dependency between subjects and handlers that should be considered in verification; i.e., verification of subject code should consider the handlers and vice versa.However, in Ptolemy the event type defines only one obligation that both the handlers and the announced piece of code must satisfy. This limits the flexibility and completeness of verification in Ptolemy. That is, some correct programs cannot be verified due to specification mismatches between the announced code and the handlers’ code. For example, when the announced code does not satisfy the specification of the entire event and handlers must make up the difference, or when the announced code has no effect, imposing a monotonic behavior on the handlers.In this paper we propose an extension to the specification features of Ptolemy that explicitly separates the specification of the handlers from the specification of the announced code. This makes verification in our new language PtolemyRely more flexible and more complete, while preserving modularity

Needle-free Mental Incisive Nerve Block: In vitro, Cadaveric, and Pilot Clinical Studies

The present study aimed to optimize Needle-Free Liquid Jet Injection (NFLJI) for Mental Incisive Nerve Blocks (MINB) and evaluate its clinical safety and feasibility. A MINB protocol was developed and optimized by series of NFLJI experiments in soft tissue phantoms and cadavers, then validated in two pilot Randomized Controlled Trials (RCT). The NFLJI penetration depth was found to be directly proportional to the supply pressure and volume. High-pressure NFLJIs (620 kPa or above) created maximum force and total work significantly greater than needle injections. Low-pressure NFLJIs (413 kPa), however, produced results similar to those of needle injections. Additionally, high-pressure NFLJIs created jet impingement pressure and maximum jet penetration pressure higher than low-pressure NFLJIs. Pilot RCTs revealed that high-pressure NFLJI caused a high risk of discomfort (60%) and paresthesia (20%); meanwhile, low-pressure NFLJI was less likely to cause complications (0%). The preliminary success rates of MINB from cadavers using NFLJIs and needles were 83.3% and 87.5%. In comparison, those from RCTs are 60% and 70%, respectively. To conclude, NFLJI supply pressure can be adjusted to achieve effective MINB with minimal complications. Furthermore, the cadaver study and pilot RCTs confirmed the feasibility for further non-inferiority RCT.Scopu