Sources, control, and effects of noise from aircraft propellers and rotors

Source noise predictions are compared with measurements for conventional low-speed propellers, for new high speed propellers (propfans), and for a helicopter. Results from a light aircraft demonstration program are described, indicating that about 5-dB reduction of flyover noise can be obtained without significant performance penalty. Sidewall design studies are described for interior noise control in light general aviation aircraft and in large transports using propfan propulsion. The weight of the added acoustic treatment is estimated and tradeoffs between weight and noise reduction are discussed. A laboratory study of passenger response to combined broadband and tonal propeller like noise is described. Subject discomfort ratings of combined tone broadband noises are compared with ratings of broadband (boundary layer) noise alone, and the relative importance of the propeller tones is examined

Extracting New Physics from the CMB

We review how initial state effects generically yield an oscillatory component in the primordial power spectrum of inflationary density perturbations. These oscillatory corrections parametrize unknown new physics at a scale $M$ and are potentially observable if the ratio $H_{infl}/M$ is sufficiently large. We clarify to what extent present and future CMB data analysis can distinguish between the different proposals for initial state corrections.Comment: Invited talk by B. Greene at the XXII Texas Symposium on Relativistic Astrophysics, Stanford University, 13-17 December 2004, (TSRA04-0001), 8 pages, LaTeX, some references added, added paragraph at the end of section 2 and an extra note added after the conclusions regarding modifications to the large k power spectra deduced from galaxy survey

Andreev Reflection in Heavy-Fermion Superconductors and Order Parameter Symmetry in CeCoIn_5

Differential conductance spectra are obtained from nanoscale junctions on the heavy-fermion superconductor CeCoIn$_5$ along three major crystallographic orientations. Consistency and reproducibility of characteristic features among the junctions ensure their spectroscopic nature. All junctions show a similar conductance asymmetry and Andreev reflection-like conductance with reduced signal (~ 10%-13%), both commonly observed in heavy-fermion superconductor junctions. Analysis using the extended Blonder-Tinkham-Klapwijk model indicates that our data provide the first spectroscopic evidence for $d_{x^2-y^2}$ symmetry. To quantify our conductance spectra, we propose a model by considering the general phenomenology in heavy fermions, the two-fluid behavior, and an energy-dependent density of states. Our model fits to the experimental data remarkably well and should invigorate further investigations.Comment: 4 pages, 4 figures; Phys. Rev. Lett., published versio

Genomic variations associated with attenuation in Mycobacterium avium subsp paratuberculosis vaccine strains

BACKGROUND: Mycobacterium avium subspecies paratuberculosis (MAP) whole cell vaccines have been widely used tools in the control of Johne's disease in animals despite being unable to provide complete protection. Current vaccine strains derive from stocks created many decades ago; however their genotypes, underlying mechanisms and relative degree of their attenuation are largely unknown. RESULTS: Using mouse virulence studies we confirm that MAP vaccine strains 316 F, II and 2e have diverse but clearly attenuated survival and persistence characteristics compared with wild type strains. Using a pan genomic microarray we characterise the genomic variations in a panel of vaccine strains sourced from stocks spanning over 40 years of maintenance. We describe multiple genomic variations specific for individual vaccine stocks in both deletion (26-32 Kbp) and tandem duplicated (11-40 Kbp) large variable genomic islands and insertion sequence copy numbers. We show individual differences suitable for diagnostic differentiation between vaccine and wild type genotypes and provide evidence for functionality of some of the deleted MAP-specific genes and their possible relation to attenuation. CONCLUSIONS: This study shows how culture environments have influenced MAP genome diversity resulting in large tandem genomic duplications, deletions and transposable element activity. In combination with classical selective systematic subculture this has led to fixation of specific MAP genomic alterations in some vaccine strain lineages which link the resulting attenuated phenotypes with deficiencies in high reactive oxygen species handling

Constraining properties of the black hole population using LISA

LISA should detect gravitational waves from tens to hundreds of systems containing black holes with mass in the range from 10 thousand to 10 million solar masses. Black holes in this mass range are not well constrained by current electromagnetic observations, so LISA could significantly enhance our understanding of the astrophysics of such systems. In this paper, we describe a framework for combining LISA observations to make statements about massive black hole populations. We summarise the constraints that LISA observations of extreme-mass-ratio inspirals might be able to place on the mass function of black holes in the LISA range. We also describe how LISA observations can be used to choose between different models for the hierarchical growth of structure in the early Universe. We consider four models that differ in their prescription for the initial mass distribution of black hole seeds, and in the efficiency of accretion onto the black holes. We show that with as little as 3 months of LISA data we can clearly distinguish between these models, even under relatively pessimistic assumptions about the performance of the detector and our knowledge of the gravitational waveforms.Comment: 12 pages, 3 figures, submitted to Class. Quantum Grav. for proceedings of 8th LISA Symposium; v2 minor changes for consistency with accepted versio