High value trees: Africa RISING science, innovations and technologies with scaling potential from the Ethiopian Highlands

United States Agency for International Developmen

Parasitological prevalence of bovine trypanosomosis in Kindo Koisha district, Wollaita zone, south Ethiopia

A cross sectional survey to determine the distribution and prevalence of trypanosomosis was conducted in Kindo Koisha district, in the Wollaita zone in southern Ethiopia. A total of 1008 adult cattle was examined at eight different localities. Dark field examination of the buffy coat, as well as stained thin blood film examination and packed cell volume (PCV) evaluation were the diagnostic techniques used. The overall prevalence of bovine trypanosomosis was 15%. Among the positive animals, 108 (71.1%), 43 (28.4%) and 1 (0.6%) were due to Trypanosoma vivax, Trypanosoma congolense and mixed infection ( T. vivax and T. congolense), respectively. The infection rate of T. vivax and T. congolense varied significantly ( P0.05). The herd average PCV values of each site decreased with increasing proportion of the positive herds of that particular site. Of the diagnostic tests employed, the microhaematocrit buffy coat technique is relatively sensitive and it has an added advantage of indicating the general condition of the animal by haematocrit measurement. In view of the risk of trypanosomosis, a control intervention through the strategic application of appropriate trypanocidal drugs is recommended. A tsetse fly control scheme to reduce host-tsetse fly contact is equally as important as chemotherapy and chemoprophylaxis against trypanosomosis.The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat v.9 was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.SOS Sahel (UK) Kindo Koisha rural development project.mn201

Chlamydia trachomatis Test-of-Cure Cannot Be Based on a Single Highly Sensitive Laboratory Test Taken at Least 3 Weeks after Treatment

Current test-of-cure practice in patients with Chlamydia trachomatis (Ct) infection is to confirm cure with a single test taken at least 3 weeks after treatment. Effectiveness of single-time-point testing however lacks a scientific evidence basis and the high sensitivity of laboratory assays nowadays in use for this purpose may compromise the clinical significance of their results. Prospectively following 59 treated Ct infections, administering care as usual, the presence of Ct plasmid DNA and rRNA was systematically assessed by multiple time-sequential measurements, i.e. on 18 samples taken per patient during 8 weeks following treatment with a single dose of 1000 mg Azythromycin. A high proportion (42%) of Ct infections tested positive on at least one of the samples taken after 3 weeks. Patients' test results showed substantial inter-individual and intra-individual variation over time and by type of NAAT used. We demonstrated frequent intermittent positive patterns in Ct test results over time, and strongly argue against current test-of-cure practice

Bringing evidence to bear for negotiating tradeoffs in sustainable agricultural intensification using a structured stakeholder engagement process

Sustainable agricultural intensification (SAI) has the potential to increase food security without detrimental effects on ecosystem services. However, adoption of SAI practices across sub-Saharan Africa has not reached transformational numbers to date. It is often hampered by lack of context-specific practices, sub-optimal understanding of tradeoffs and synergies among stakeholders, and lack of approaches that bring diverse evidence sources together with stakeholders to collectively tackle complex problems. In this study, we asked three interconnected questions: (i) What is the accessibility and use of evidence for SAI decision making; (ii) What tools could enhance access and interaction with evidence for tradeoff analysis; and (iii) Which stakeholders must be included? This study employed a range of research and engagement methods including surveys, stakeholder analysis, participatory trade-off assessments and co-design of decision dashboards to better support evidence-based decision making in Zambia, Tanzania and Ethiopia. At the inception, SAI evidence was accessible and used by less than half of the decision makers across the three countries and online dashboards hold promise to enhance access. Many of the stakeholders working on SAI were not collaborating and tradeoff analysis was an under-utilized tool. Structured engagement across multiple stakeholder groups with evidence is critical