449 research outputs found

    Automated Rendezvous and Docking Using Tethered Formation Flight

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    This paper analyzes capture strategies for tether-based autonomous rendezvous and docking. Once both spacecrafts are connected by tethers, docking is achieved through the use of reaction wheels and tether motors without the use of propellant. Autonomous rendezvous and docking is crucial for many upcoming missions including on-orbit servicing and potential Mars missions. The tether-based capture strategies investigated are a spin-up tether deployment and a free-flying child spacecraft attaching the tether. These strategies are compared to a traditional two-agent propulsive docking strategy. The capture strategies are simulated from initial orbit through to completed dock, with the total fuel consumption and dock time compared, along with initial pointing/location requirements. In addition to having lower fuel cost, the tether-based strategies are also more reliable due to redundancy, since tethers can be reeled back in and multiple tethers can be stored for use in case of primary tether failure

    Autonomous In-Orbit Satellite Assembly from a Modular Heterogeneous Swarm

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    This paper presents a decentralized, distributed guidance and control scheme to combine a heterogeneous swarm of component satellites into a large satellite structure. The component satellites for the heterogeneous swarm are chosen to promote flexibility in final shape inspired by crystal structures and Islamic tile art. After the ideal fundamental building blocks are selected, basic nanosatellite-class satellite designs are made to assist in simulations involving attitude control. The Swarm Orbital Construction Algorithm (SOCA) is a guidance and control algorithm to allow for the limited type heterogeneity and docking ability required for in-orbit assembly. The algorithm consists of two parts, a distributed auction which uses barrier functions to ensure the proper agent selection for each target, and a trajectory generation portion which leverages model predictive control and sequential convex programming to achieve optimal collision-free trajectories to the desired target point even with nonlinear system dynamics. The optimization constraints use a boundary layer to determine whether the collision avoidance or the docking constraints should be applied. The algorithm was tested in a simulated perturbed 6-DOF spacecraft dynamic environment for planar and out-of-plane final structures and on two robotic platforms, including a swarm of frictionless spacecraft simulation robots

    Pennsylvania Folklife Vol. 25, Folk Festival Supplement

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    • Quilts, Quilts, Quilts • America\u27s Heritage is Endowed with Contributions of the Pennsylvania Dutch • The Hospitality Tent: H is for Help - That\u27s What it\u27s all About • Pottery: A Folk Art Expressing the Most in Simplest Terms • It Never Rains on our Parade - On the Fourth of July • Vegetable Dyeing at the Kutztown Folk Festival • Festival Focus • Folk Festival Program • Festival Foods: The Original Touch of the Dutch • Ursinus College Studies at the Festival • Behind the Scenes of We Like Our Country, But We Love Our God • Reverse Glass Tinsel Painting • Tin, Tole and Independencehttps://digitalcommons.ursinus.edu/pafolklifemag/1069/thumbnail.jp

    Systemic Gene Delivery in Large Species for Targeting Spinal Cord, Brain, and Peripheral Tissues for Pediatric Disorders

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    Adeno-associated virus type 9 (AAV9) is a powerful tool for delivering genes throughout the central nervous system (CNS) following intravenous injection. Preclinical results in pediatric models of spinal muscular atrophy (SMA) and lysosomal storage disorders provide a compelling case for advancing AAV9 to the clinic. An important translational step is to demonstrate efficient CNS targeting in large animals at various ages. In the present study, we tested systemically injected AAV9 in cynomolgus macaques, administered at birth through 3 years of age for targeting CNS and peripheral tissues. We show that AAV9 was efficient at crossing the blood–brain barrier (BBB) at all time points investigated. Transgene expression was detected primarily in glial cells throughout the brain, dorsal root ganglia neurons and motor neurons within the spinal cord, providing confidence for translation to SMA patients. Systemic injection also efficiently targeted skeletal muscle and peripheral organs. To specifically target the CNS, we explored AAV9 delivery to cerebrospinal fluid (CSF). CSF injection efficiently targeted motor neurons, and restricted gene expression to the CNS, providing an alternate delivery route and potentially lower manufacturing requirements for older, larger patients. Our findings support the use of AAV9 for gene transfer to the CNS for disorders in pediatric populations
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