478 research outputs found

    Grazing behavior of lactating Murrah buffalo cows supplemented with cupuassu byproduct.

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    The goal of this work was to evaluate grazing behavior of lactating Murrah buffalo cows supplemented with cupuassu byproduct containing 16.8, 51.4, 8.3, 83.5 and 3.4% of ether extract (EE), neutral detergent fiber (NDF), crude protein (CP), total digestible nutrients (TDN) and nonfibrous carbohydrate (NFC), respectively. Experimental rations were balanced for reaching levels of 22.0 % of crude protein (CP) and 80.1 % of total digestible nutrient (TDN)

    Avaliação do tempo de cultivo e diâmetro da estaca no enraizamento de mudas de Oxalis psoraleoides Kunth. (Oxalidaceae).

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    Este trabalho teve como objetivo avaliar o tempo de cultivo e o diâmetro da estaca mais indicados para a produção de mudas de Oxalis psoraleoides

    Developing innovative systems for reinforced masonry walls

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    The Commission of the European Communities has recently funded a CRAFT research project aimed at developing innovative systems for load and non-load-bearing reinforced masonry walls. The project involves twelve partners coming from four different European countries, among which there are universities and research centres, small and medium enterprises for the production of clay and concrete units and mortars, a company for advanced metal products and industrial associations of brick and block producers. The development of the reinforced masonry walls is based on the advancement of vertical reinforcement and fastenings, of mortar and concrete and on their integration with special clay and concrete blocks for the definition of new construction systems. The foreseen advantages are: new possibilities for masonry; more economical construction; quality increase for masonry walls; crack-free and earthquake resistant construction. The project follows three steps: assessment of the technical and economical feasibility of the envisaged construction technologies by means of extensive experimental and numerical activities; construction of prototypes as demonstration of the proposed technologies and materials; in situ testing to completely validate the systems. In the present contribution, an overview of the main objectives and steps of the project is given. Furthermore, the different construction systems that are being developed and designed are described. The main fields of application and the main technical problems encountered for the different construction systems is described, together with the experimental program outlined in order to characterize their mechanical behaviour under different serviceability and ultimate conditions

    The Place and Value of Sodium-Glucose Cotransporter 2 Inhibitors in the Evolving Treatment Paradigm for Type 2 Diabetes Mellitus: A Narrative Review

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    Over recent years, the expanding evidence base for sodium-glucose cotransporter-2 inhibitor (SGLT2i) therapies has revealed benefits beyond their glucose-lowering efficacy in the treatment of Type 2 diabetes mellitus (T2DM), resulting in their recognition as cardiorenal medicines. While SGLT2is continue to be recommended among the second-line therapies for the treatment of hyperglycaemia, their true value now extends to the prevention of debilitating and costly cardiovascular and renal events for high-risk individuals, with particular benefit shown in reducing major adverse cardiac events and heart failure (HF) and slowing the progression of chronic kidney disease. However, SGLT2i usage is still suboptimal among groups considered to be at greatest risk of cardiorenal complications. The ongoing coronavirus disease 2019 (COVID-19) pandemic has intensified financial pressures on healthcare systems, which may hamper further investment in newer effective medicines. Emerging evidence indicates that glycaemic control should be prioritised for people with T2DM in the era of COVID-19 and practical advice on the use of T2DM medications during periods of acute illness remains important, particularly for healthcare professionals working in primary care who face multiple competing priorities. This article provides the latest update from the Improving Diabetes Steering Committee, including perspectives on the value of SGLT2is as cost-effective therapies within the T2DM treatment paradigm, with particular focus on the latest published evidence relating to the prevention or slowing of cardiorenal complications. The implications for ongoing and future approaches to diabetes care are considered in the light of the continuing coronavirus pandemic, and relevant aspects of international treatment guidelines are highlighted with practical advice on the appropriate use of SGLT2is in commonly occurring T2DM clinical scenarios. The ‘SGLT2i Prescribing Tool for T2DM Management’, previously published by the Steering Committee, has been updated to reflect the latest evidence and is provided in the Supplementary Materials to help support clinicians delivering T2DM care
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