Hydrogen 2p--2s transition: signals from the epochs of recombination and reionization

We propose a method to study the epoch of reionization based on the possible observation of 2p--2s fine structure lines from the neutral hydrogen outside the cosmological H {\sc ii} regions enveloping QSOs and other ionizing sources in the reionization era. We show that for parameters typical of luminous sources observed at $z \simeq 6.3$ the strength of this signal, which is proportional to the H {\sc i} fraction, has a brightness temperature $\simeq 20 \mu K$ for a fully neutral medium. The fine structure line from this redshift is observable at $\nu \simeq 1 \rm GHz$ and we discuss prospects for the detection with several operational and future radio telescopes. We also compute the characteristics of this signal from the epoch of recombination: the peak brightness is expected to be $\simeq 100 \mu K$; this signal appears in the frequency range 5-10 MHz. The signal from the recombination era is nearly impossible to detect owing to the extreme brightness of the Galactic emission at these frequencies.Comment: 17 pages, 1 figure, to appear in Ap

PERFORMANCE OF SOLAR PHOTOVOLTAIC MODULE THROUGH COMBINED AIR AND WATER COOLING IN WARM AND HUMID CLIMATIC CONDITION OF INDIA

A study was conducted to evaluate the performance of solar photovoltaic module through combined air and water cooling arrangements in warm and humid climatic condition i.e. in Odisha in India during winter and summer months. Solar photovoltaic system requires neither fuel nor produces any pollutant resulting into its increased importance in today’s energy sector. The electrical output from a solar panel is a function of its efficiency and some other controlling parameters which affects the same. One of the major parameters controlling the efficiency of the panel is the temperature as it goes on increasing while using the panel in the sun. About 31 % of the incident solar radiation on the panel is converted into the useful energy and the rest part is stored in its back side causing the rise of temperature and adversely affecting its output. The stored thermal energy is of no use and decreases the durability of the in-built components of the panel due to the impact of severe thermal stresses on them resulting into reduction in its life span and conversion capability. The simplest way to enhance the efficiency of the panel is to incorporate the various cooling arrangements such as air cooling, water cooling and combined air and water cooling and assessing their effectiveness without any cooling arrangement. From the studies, it was observed that the efficiencies of solar panel were enhanced in the range of 8-11 %, 12-15% and 16-20% in air, water and combined air and water cooling respectively compared to without cooling in a clear day

DLCQ of Fivebranes, Large N Screening, and L^2 Harmonic Forms on Calabi Manifolds

We find one explicit L^2 harmonic form for every Calabi manifold. Calabi manifolds are known to arise in low energy dynamics of solitons in Yang-Mills theories, and the L^2 harmonic form corresponds to the supersymmetric ground state. As the normalizable ground state of a single U(N) instanton, it is related to the bound state of a single D0 to multiple coincident D4's in the non-commutative setting, or equivalently a unit Kaluza-Klein mode in DLCQ of fivebrane worldvolume theory. As the ground state of nonabelian massless monopoles realized around a monopole-``anti''-monopole pair, it shows how the long range force between the pair is screened in a manner reminiscent of large N behavior of quark-anti-quark potential found in AdS/CFT correspondence.Comment: LaTeX, 23 page

Snowcover Simulation Model : A Review

Numerical simulation of seasonal snowcover has attracted the interest of many scientists in the recent past. The present paper summarises chronologically developments in the understanding of snow properties and discusses various modelling approaches towards simulating the snowpack numerically. The authors describe the evolution of snowcover and the intricate relationship between the evolving snowpack and the atmosphere. The governing equations that describe the evolution of snowcover have been discussed. The merits and limitations of each equation pescribing a single process have been explained. Modelling strategies adopted by various workers have been analysed, and lastly the requirements of a perfect model have been brought out. In the absence of complete answers to many other processes, a strategy for the development of an operational snowcover model has been discussed

Maladaptive striatal plasticity and abnormal reward-learning in cervical dystonia

In monogenetic generalized forms of dystonia, in vitro neurophysiological recordings have demonstrated direct evidence for abnormal plasticity at the level of the cortico‐striatal synapse. It is unclear whether similar abnormalities contribute to the pathophysiology of cervical dystonia, the most common type of focal dystonia. We investigated whether abnormal cortico‐striatal synaptic plasticity contributes to abnormal reward‐learning behavior in patients with focal dystonia. Forty patients and 40 controls performed a reward gain and loss avoidance reversal learning task. Participant's behavior was fitted to a computational model of the basal ganglia incorporating detailed cortico‐striatal synaptic learning rules. Model comparisons were performed to assess the ability of four hypothesized receptor specific abnormalities of cortico‐striatal long‐term potentiation (LTP) and long‐term depression (LTD): increased or decreased D1:LTP/LTD and increased or decreased D2: LTP/LTD to explain abnormal behavior in patients. Patients were selectively impaired in the post‐reversal phase of the reward task. Individual learning rates in the reward reversal task correlated with the severity of the patient's motor symptoms. A model of the striatum with decreased D2:LTP/ LTD best explained the patient's behavior, suggesting excessive D2 cortico‐striatal synaptic depotentiation could underpin biased reward‐learning in patients with cervical dystonia. Reversal learning impairment in cervical dystonia may be a behavioral correlate of D2‐specific abnormalities in cortico‐striatal synaptic plasticity. Reinforcement learning tasks with computational modeling could allow the identification of molecular targets for novel treatments based on their ability to restore normal reward‐learning behavior in these patients

Primordial magnetic fields and the HI signal from the epoch of reionization

The implication of primordial magnetic-field-induced structure formation for the HI signal from the epoch of reionization is studied. Using semi-analytic models, we compute both the density and ionization inhomogeneities in this scenario. We show that: (a) The global HI signal can only be seen in emission, unlike in the standard $\Lambda$CDM models, (b) the density perturbations induced by primordial fields, leave distinctive signatures of the magnetic field Jeans' length on the HI two-point correlation function, (c) the length scale of ionization inhomogeneities is \la 1 \rm Mpc. We find that the peak expected signal (two-point correlation function) is $\simeq 10^{-4} \rm K^2$ in the range of scales $0.5\hbox{-}3 \rm Mpc$ for magnetic field strength in the range $5 \times 10^{-10} \hbox{-}3 \times 10^{-9} \rm G$. We also discuss the detectability of the HI signal. The angular resolution of the on-going and planned radio interferometers allows one to probe only the largest magnetic field strengths that we consider. They have the sensitivity to detect the magnetic field-induced features. We show that thefuture SKA has both the angular resolution and the sensitivity to detect the magnetic field-induced signal in the entire range of magnetic field values we consider, in an integration time of one week.Comment: 19 pages, 5 figures, to appear in JCA

11 beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle

OBJECTIVE: Glucocorticoid excess is characterized by increased adiposity, skeletal myopathy, and insulin resistance, but the precise molecular mechanisms are unknown. Within skeletal muscle, 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) converts cortisone (11-dehydrocorticosterone in rodents) to active cortisol (corticosterone in rodents). We aimed to determine the mechanisms underpinning glucocorticoid-induced insulin resistance in skeletal muscle and indentify how 11beta-HSD1 inhibitors improve insulin sensitivity. \ud RESEARCH DESIGN AND METHODS: Rodent and human cell cultures, whole-tissue explants, and animal models were used to determine the impact of glucocorticoids and selective 11beta-HSD1 inhibition upon insulin signaling and action. \ud RESULTS: Dexamethasone decreased insulin-stimulated glucose uptake, decreased IRS1 mRNA and protein expression, and increased inactivating pSer$^{307}$ insulin receptor substrate (IRS)-1. 11beta-HSD1 activity and expression were observed in human and rodent myotubes and muscle explants. Activity was predominantly oxo-reductase, generating active glucocorticoid. A1 (selective 11beta-HSD1 inhibitor) abolished enzyme activity and blocked the increase in pSer$^{307}$ IRS1 and reduction in total IRS1 protein after treatment with 11DHC but not corticosterone. In C57Bl6/J mice, the selective 11beta-HSD1 inhibitor, A2, decreased fasting blood glucose levels and improved insulin sensitivity. In KK mice treated with A2, skeletal muscle pSer$^{307}$ IRS1 decreased and pThr$^{308}$ Akt/PKB increased. In addition, A2 decreased both lipogenic and lipolytic gene expression.\ud CONCLUSIONS: Prereceptor facilitation of glucocorticoid action via 11beta-HSD1 increases pSer$^{307}$ IRS1 and may be crucial in mediating insulin resistance in skeletal muscle. Selective 11beta-HSD1 inhibition decreases pSer$^{307}$ IRS1, increases pThr$^{308}$ Akt/PKB, and decreases lipogenic and lipolytic gene expression that may represent an important mechanism underpinning their insulin-sensitizing action

An HST Search for Lyman Continuum Emission From Galaxies at z=1.1--1.4

If enough of their Lyman limit continuum escapes, star-forming galaxies could be significant contributors to the cosmic background of ionizing photons. To investigate this possibility, we obtained the first deep imaging in the far ultraviolet of eleven bright blue galaxies at intermediate redshift (z=1.1--1.4). NO Lyman continuum emission was detected. Sensitive, model-independent, upper limits of typically 2 x 10**-19 erg/sec/cm2/Ang were obtained for the ionizing flux escaping from these normal galaxies. This corresponds to lower limits on the observed ratio of 1500 to 700Ang flux of 150 up to 1000. Based on a wide range of stellar synthesis models, this suggests that less than 6%, down to less than 1%, of the available ionizing flux emitted by hot stars is escaping these galaxies. The magnitude of this spectral break at the Lyman l imit confirms that the basic premise of `Lyman break' searches for galaxies at high redshift can also be applied at intermediate redshifts. This implies that the integrated contribution of galaxies to the UV cosmic background at z around 1.2 is less than 15%, and may be less than 2%.Comment: 20 manuscript pages, which includes two tables and two figures. To be published in 1 December 2003 issue of The Astrophysical Journa

Small Quadrupole Deformation for the Dipole Bands in 112In

High spin states in $^{112}$In were investigated using $^{100}$Mo($^{16}$O, p3n) reaction at 80 MeV. The excited level have been observed up to 5.6 MeV excitation energy and spin $\sim$ 20$\hbar$ with the level scheme showing three dipole bands. The polarization and lifetime measurements were carried out for the dipole bands. Tilted axis cranking model calculations were performed for different quasi-particle configurations of this doubly odd nucleus. Comparison of the calculations of the model with the B(M1) transition strengths of the positive and negative parity bands firmly established their configurations.Comment: 10 pages, 11 figures, 2 table