83 research outputs found
Cytocompatibility of Medical Biomaterials Containing Nickel by Osteoblasts: a Systematic Literature Review
The present review is based on a survey of 21 studies on the cytocompatibility of medical biomaterials containing nickel, as assessed by cell culture of human and animal osteoblasts or osteoblast-like cells. Among the biomaterials evaluated were stainless steel, NiTi alloys, pure Ni, Ti, and other pure metals. The materials were either commercially available, prepared by the authors, or implanted by various techniques to generate a protective layer of oxides, nitrides, acetylides. The observation that the layers significantly reduced the initial release of metal ions and increased cytocompatibility was confirmed in cell culture experiments. Physical and chemical characterization of the materials was performed. This included, e.g., surface characterization (roughness, wettability, corrosion behavior, quantity of released ions, microhardness, and characterization of passivation layer). Cytocompatibility tests of the materials were conducted in the cultures of human or animal osteoblasts and osteoblast-like cells. The following assays were carried out: cell proliferation and viability test, adhesion test, morphology (by fluorescent microscopy or SEM). Also phenotypic and genotypic markers were investigated. In the majority of works, it was found that the most cytocompatible materials were stainless steel and NiTi alloy. Pure Ni was rendered and less cytocompatible. All the papers confirmed that the consequence of the formation of protective layers was in significant increase of cytocompatibility of the materials. This indicates the possible further modifications of the manufacturing process (formation of the passivation layer)
Investigating the correlation between some of the properties of plasma nitrided AISI 316L stainless steel
Preliminary viability studies of fibroblastic cells cultured on microcrystalline and nanocrystalline diamonds produced by chemical vapour deposition method
LDL receptor knock-out mice show impaired spatial cognition with hippocampal vulnerability to apoptosis and deficits in synapses
A study on the microstructural property and thermal property of Ti-alloys without Al as biomaterials
HIF-2a, but not HIF-1a, is essential for hypoxic induction of class IIIb-tubulin expression in human glioblastoma cells
CERVOXYInternational audienc
Effects of betaIII-tubulin knockdown on the growth of glioblastoma cells and on the efficacy of chemotherapies
CERVOXYNational audienc
DĂ©veloppement de constructions inductibles par lâhypoxie : application Ă lâinhibition de lâĂ©rythropoĂŻĂ©tine dans les glioblastomes.
CERVOXYNational audienc
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