The value of figs to chimpanzees

Nine Ugandan figs have consistent differences in nutrient concentration between the pulp and seed fractions. Pulp has more water-soluble carbohydrates, complex carbohydrates, calories, and ash, while the seed fraction has more condensed tannins, lipids, and fiber. Because species differ, nutrient concentration in pulp could not be predicted from analysis of whole figs. Chimpanzees in Kibale Forest relied heavily on figs throughout 29 months, feeding relatively intensely at large trees. Fig size varied between species, between individuals of the same species, and between fruiting cycles of the same tree. Larger figs had higher water concentrations but still led to higher rates of nutrient intake per minute for chimpanzees, monkeys, and hornbills. Chimpanzees ate more than 40 cal/min, excluding calories derived from insoluble fiber, when harvesting large figs.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44560/1/10764_2005_Article_BF02192634.pd

Associated features in females with an FMR1 premutation

Abstract Changes in the fragile X mental retardation 1 gene (FMR1) have been associated with specific phenotypes, most specifically those of fragile X syndrome (FXS), fragile X tremor/ataxia syndrome (FXTAS), and fragile X primary ovarian insufficiency (FXPOI). Evidence of increased risk for additional medical, psychiatric, and cognitive features and conditions is now known to exist for individuals with a premutation, although some features have been more thoroughly studied than others. This review highlights the literature on medical, reproductive, cognitive, and psychiatric features, primarily in females, that have been suggested to be associated with changes in the FMR1 gene. Based on this review, each feature is evaluated with regard to the strength of evidence of association with the premutation. Areas of need for additional focused research and possible intervention strategies are suggested

A family with two female siblings with compound heterozygous FMR1 premutation alleles

Premutation alleles (55-200 CGG repeats) of the fragile X mental retardation (FMR1) gene have been linked to various types of clinical involvement ranging from mood and anxiety disorders to immunological disorders and executive function deficits. Carrier females typically have a premutation allele and a normal allele (<55 CGG repeats). Although rare, seven cases of females that carry two expanded alleles (compound heterozygous premutation) have been reported. Here, we report on four members of a family including two compound heterozygous premutation sisters with similar CGG allele sizes, affected with different levels of clinical severity