Anton A. Fedjašin, Liberals under Autocracy: Modernization and Civil Society in Russia, 1866-1904

Ce livre, issu de la thèse d’A. Fedjašin, vise à réhabiliter le libéralisme russe de la fin du xixe siècle en l’opposant au peu populaire libéralisme des années 1990. Pour ce faire, il se focalise sur l’histoire d’une revue mensuelle, le Vestnik Evropy, et sur les quatre individus qui en étaient l’âme entre 1866 et le tournant du siècle. L’A. se rattache à la fois à l’historiographie qui entend réhabiliter le libéralisme d’Europe centrale et à l’historiographie qui s’intéresse à l’intelligent..

Santa Fe Daily New Mexican, 02-09-1894

https://digitalrepository.unm.edu/sfnm_news/5622/thumbnail.jp

Lloyd B. Gurney, Betty Gurney, Paul Gurney, Donna S. Gurney, Lee A. Jeppson, LaRAE G. Jeppson, and LaRee Smith v. Randy G. Young, Blake Jumper, Stone River Development, LLC, RCP Land Investment, LLC, and R.G. Young, Inc. : Brief of Appellant

Benoît Jean-Daniel. Paul T. Fuhrmann, Extraordinary Christianity. The life and thought of Alexander Vinet. Philadelphie, the Westminster Press, 1964. In: Revue d'histoire et de philosophie religieuses, 46e année n°2,1966. p. 195

The Efficacy of Aerobic Exercise and Relaxation Technique in Fatigue among Children with Acute Lymphoblastic Leukemia: A Comparative study

INTRODUCTION : Childhood cancer is one of the leading cause of death by disease among which Acute Lymphoblastic Leukemia (ALL) accounts for 30% of all the malignancies. ALL is the most common form of pediatric leukemia which is also known as Acute Lymphocytic or Acute Lymphoid Leukemia. Incidence is approximately 3-4 cases per 100,000 children below 15 years with peak incidence below 2-5 years of age. In most of the countries, the incidence rate in children was approximately four times than that of the adults. Studies have shown a 98% cure rate in ALL. But even with these survival rates in pediatric population, only half of the ALL patients survived 5 years. Exact etiology of ALL is still unknown but common etiological factors include ionizing radiations, congenital anomalies, chemical agents like Benzene and Immunodeficiency syndromes. Many studies have reported the risk factors like Down syndrome, Erbstien Barr Virus (EBV) infections, parental history of fetal loss, miscarriage, perinatal exposure to pesticides and still birth to be reasons for developing leukemia. The pathogenesis of ALL is assumed to be the neoplasm arising from the clonal proliferation of immature cells of hemopoetic system which are characterized by the aberrant or arrested differentiation. The associated complications of ALL include musculoskeletal, Central Nervous System (CNS) and other systemic complications. Recent study have shown that 2% of the boys diagnosed with ALL shows testicular enlargement. Neural complications like pain, paresthesia and reduced deep tendon reflexes have been reported in various studies. Musculoskeletal complications like impaired gross motor and fine motor performances, increased fatigue, compromised ROM, strength and endurance have also been identified. Unfortunately, fatigue has become the most debilitating symptom in patients with cancer. It was reported to be an intensive disability among cancer patients as it induces inactivity which on prolonged rest lead to muscle wasting and loss of endurance. Fatigue affects quality of life to about 60% in cancer patients. But limited focus was given to those groups recognized with fatigue complaining unique experiences. AIM OF THE STUDY : This study was aimed to find out the effect of aerobic training and relaxation technique on fatigue in children with ALL. OBJECTIVES : 1. To find out the effectiveness of CSF in aerobic training among children with ALL. 2. To find out the effectiveness of PSF in aerobic training among children with ALL. 3. To find out the effectiveness of CSF in relaxation technique among children with ALL. 4. To find out the effectiveness of PSF in relaxation technique among children with ALL. 5. To compare the outcomes of CSF between the aerobic training and relaxation technique among children with ALL. 6. To compare the outcomes of PSF between the aerobic training and relaxation technique among children with ALL. METHODOLOGY : Study Design : A comparative study. Study Setting : Pediatric inpatient oncology ward, Sri Ramakrishna Institute of Oncology and Research, Coimbatore. Sampling Technique : A convenience sampling. Sample Size : A total of 30 acute lymphoblastic leukemia patients was selected on the basis of inclusion criteria and conveniently allocated into two groups of 15 each. Both the groups were designed for experimentation. Study Duration : The study was conducted over a period of 10 months. Treatment Duration : The treatment duration was 4 weeks. Inclusion Criteria : • Children undergoing chemotherapy. • Aged between 5-12. • Both gender. • Children with preserved cardiac function. • Children able to accept and follow verbal instructions. • Children complaining of fatigue. Exclusion Criteria : • Children with unstable cardiac function. • Children with platelet count less than 3000/uL. • Children with recent surgeries(less than 3 months). • Children with congenital musculoskeletal anomalies. • Children with visual and hearing deficits. • Children with systemic complications. RESULTS : The mean values of aerobic training group (27.7) is greater than the relaxation training group (23.3). The calculated ‘t’ value is 2.848 which is greater than the table value (2.048). The study showed that there is significant difference in child fatigue scale level of aerobic training group and relaxation training group at the level of p<0.05. This shows that aerobic training is effective than the relaxation training in improvement of fatigue among ALL children. CONCLUSION : The study confirmed the effects of both Aerobic exercise and Relaxation technique which could reduce the level of fatigue among children with ALL. The aerobic training yield better results compared to relaxation training in reducing fatigue level among ALL children

"The women question" in the life and works of Aleksei Sergeevich Suvorin

PhDThis thesis traces the influence of ‘the woman question’ on the life and writings of Aleksei Sergeevich Suvorin (1834–1912), an eminent journalist, publisher and editor of the newspaper Novoe vremia. My research is based on Suvorin’s previously unexamined contribution to public debate on this question and also includes an overview of his fictional work. The thesis represents a case study and brings to light material critical to Suvorin’s biography. This is important because Suvorin’s personal case exemplifies the difficulties which up-and-coming men of the intelligentsia encountered in responding to the rapid and drastic social changes to which they were exposed, and in particular to the redistribution of influence and authority between men and women. Based on documentary sources and in particular on new archival material the thesis analyses the extent to which Suvorin’s life was affected by his relationship with strong and domineering women and examines the impact of these biographical factors on his writings. This case study provides an important insight into the development of the Russian liberal idea commonly referred to as the ‘emancipation of women’. The thesis is organized into an Introduction followed by three chapters, a Conclusion, a Bibliography, and an Appendix. Developing my argument, I apply a chronological principle, dividing Suvorin’s life and works into three periods presented in chapters 1–3; these periods can be matched up in approximate terms with the three stages of the women’s movement in Russia. The first period starts in 1858 and ends in 1873, the turning point in Suvorin’s life and career; within this period the women’s movement in Russia had worked out its ideology and some tactical moves. The second period (1874–1890) covers Suvorin’s career successes and his concomitant midlife crisis; during this time, the women’s movement was also experiencing a crisis of its own. The third period (1891–1912) marks Suvorin’s personal decline against the rapid politicization of the Russian women’s movement. In the Conclusion section I develop an overview of the contribution which Suvorin made to the emergence of ‘public opinion’ in late Imperial Russia and I end by attempting a definition of his ideological position within the context of Russian liberal thought. The material analysed in the thesis makes it possible to place Suvorin amongst the so-called conservative liberals, at least as regards his views on the emancipation of women. The Appendix includes translations of the Russian quotes used in the main text of the thesis

The transformation of higher learning 1860-1930: expansion, diversification, social opening and professionalization in England, Germany, Russia and the United States

"The debate about the current (or perhaps perennial) crises of higher education suffers from a lack of temporal and comparative perspective. Concerned with solving immediate policy problems, scholars and administrators tend to argue as if their present predicaments were unique. However academic unemployment, curricular disintegration, inequality of opportunity and vocationalism are neither particularly new nor limited to the United States. While the pas cannot merely be used as a quarry for building blocks for the future, and comparisons, if superficial, mislead more than enlighten, both can provide a clearer awareness of the dynamics of change which underlie some of the recent difficulties. Although the last great upheaval which produced mass higher education has dwarfed all previous development, many of its problems of size, institutional structure, social composition and professional orientation have resulted from the prior change from a traditional to a modern system around the turn of the century. Hence a closer look at the patterns, causes and consequences of that transformation of higher learning in the West suggests a broader as well as a longer view on the antecedents of the recent malaise and a more critical sense of the connection between education and social change. The present volume attempts to build upon the new social history of higher education." "Therefore this volume employs a cooperative approach, which attempts close coordination, seeks to present some primary statistics and tries to provide an interdisciplinary historical perspective. By concentrating on four important countries such as Britain, Germany, Russia and the United States as well as on four overriding topics such as expansion, diversification, social opening and professionalisation, it focuses both on the common dynamics of the transformation and individual national peculiarities." (author's abstract

Expression and characteristics of ion channels in osteoblasts : putative roles for TRP and K+ channels

Bone turnover is regulated by a cocktail of hormones and signalling factors controlling key cell processes such as proliferation, differentiation, mineralisation and apoptosis. Disruption to the overall mineralisation-resorption balance leads to bone disorders, such as osteoporosis - a 'silent' disease affecting around 7 million people in England and Wales. Ion channels that are presumed targets for bone signalling factors include voltage-gated K channels, ATP-dependent K channels and transient receptor potential TRP channels, and several of these channel-types reportedly have roles in cell proliferation, apoptosis, and differentiation in various tissues. This Thesis shows that human osteoblasts express a number of channels in these families, including maxi-K, ATP-dependent K channels, TRPV1 and TRPM7. The maxi-K channel, displaying characteristic electrophysiological hallmarks, is abundant in patch-clamp recordings of primary human osteoblasts implying a functional role, and the Katp agonist pinacidil is shown to promote osteoblast proliferation. Electrophysiological evidence for the TRPVI channel is not found, although the mRNA signal for a TRPVI splice variant TRPVlb may provide an answer, as it renders the channel less sensitive to capsaicin and protons. However, Ca imaging indicates that osteoblastic TRPV1 channels allow Ca2 influx, and are sensitive to 1 &micro;M capsaicin and protons. In functional studies the TRPVI ligands capsaicin and capsazepine do not influence mineralisation, but interestingly the TRPVI agonists capsaicin, resiniferatoxin and anandamide appear to prevent differentiation of osteoblastic pre-cursor cells to adipocytes, and instead encourage maturation along the osteoblast pathway, whilst TRPV1 antagonists do not affect adipocyte differentiation. In conclusion, a number of K channels and the TRPV1 channel are expressed in osteoblasts and may have important putative roles in osteoblast cell function. Further steps are required to confirm this before the channels can be considered targets for drug development to treat bone disorders.EThOS - Electronic Theses Online ServiceGBUnited Kingdo