Power Allocation for Conventional and Buffer-Aided Link Adaptive Relaying Systems with Energy Harvesting Nodes

Energy harvesting (EH) nodes can play an important role in cooperative communication systems which do not have a continuous power supply. In this paper, we consider the optimization of conventional and buffer-aided link adaptive EH relaying systems, where an EH source communicates with the destination via an EH decode-and-forward relay. In conventional relaying, source and relay transmit signals in consecutive time slots whereas in buffer-aided link adaptive relaying, the state of the source-relay and relay-destination channels determines whether the source or the relay is selected for transmission. Our objective is to maximize the system throughput over a finite number of transmission time slots for both relaying protocols. In case of conventional relaying, we propose an offline and several online joint source and relay transmit power allocation schemes. For offline power allocation, we formulate an optimization problem which can be solved optimally. For the online case, we propose a dynamic programming (DP) approach to compute the optimal online transmit power. To alleviate the complexity inherent to DP, we also propose several suboptimal online power allocation schemes. For buffer-aided link adaptive relaying, we show that the joint offline optimization of the source and relay transmit powers along with the link selection results in a mixed integer non-linear program which we solve optimally using the spatial branch-and-bound method. We also propose an efficient online power allocation scheme and a naive online power allocation scheme for buffer-aided link adaptive relaying. Our results show that link adaptive relaying provides performance improvement over conventional relaying at the expense of a higher computational complexity.Comment: Submitted to IEEE Transactions on Wireless Communication

Variantes anatomiques de l’os temporal a preciser au chirurgien

L’os temporal présente plusieurs variantes dont certaines peuvent avoir un impact chirurgical. La chirurgie de l’oreille est non dénuée de risques. Les variantes anatomiques de l’os temporal sont importantes à connaitre et à préciser dans le compte rendu radiologique avant toute intervention sur l’oreille. La TDM est l’examen clé pour le bilan morphologique de toute oreille.Mots Clés : Variantes anatomiques, os temporal, TDM, risques.The temporal bone has several variants, some of which may impact surgical. The ear surgery is not without risks. The anatomic variations of the temporal bone is important to know and specify in the radiological reports before working on the ear. The CT is the key for the morphological assessment of any ear.Keys Words: Anatomic variations, temporal bone, CT, risk

Structural Analysis of Nano Core PCF With Fused Cladding for Supercontinuum Generation in 6G Networks

The Sixth Generation (6G) networks have identified the use of frequency range between 95 GHz and 3 THz with a targeted data rate of 1 Terabytes/second at the access network for holographic video applications. As is demands broadening of spectrum at the core network, this paper proposes a Supercontinuum Generation (SCG) through photonic crystal fiber (PCF) as it provides excellent broadening of the optical spectrum. Discussed in the paper is supercontinuum generation at high pumping power as per the standards specified by the International Telecommunications Union. The proposed PCF is designed with silicon nanocrystal core and the cladding microstructures is arranged in a fusion approach to effectively optimize the optical parameters such as dispersion, nonlinearity, birefringence, group-velocity dispersion, and confinement loss. The fused cladding comprises of a flower-cladding assembly in which air-holes arrangement is inspired from petals in a pleated structure. Such arrangement is shown here to provide high nonlinearity and negative dispersion for high power supercontinuum generation. The novel nanocore assembly with improved structural constraints delivers a non-linearity of 6.37 × 106 W−1 km−1 and a negative dispersion of −142.1 (ps/nm-km) at 1,550 nm. Moreover, a supercontinuum spectrum is generated using different pulse widths ranging from 350 to 650 ps with 25 kW pump power for PCF lengths of 10 and 15 mm

Design of a Planar Sensor Based on Split-Ring Resonators for Non-Invasive Permittivity Measurement

The permittivity of a material is an important parameter to characterize the degree of polarization of a material and identify components and impurities. This paper presents a non-invasive measurement technique to characterize materials in terms of their permittivity based on a modified metamaterial unit-cell sensor. The sensor consists of a complementary split-ring resonator (C-SRR), but its fringe electric field is contained with a conductive shield to intensify the normal component of the electric field. It is shown that by tightly electromagnetically coupling opposite sides of the unit-cell sensor to the input/output microstrip feedlines, two distinct resonant modes are excited. Perturbation of the fundamental mode is exploited here for determining the permittivity of materials. The sensitivity of the modified metamaterial unit-cell sensor is enhanced four-fold by using it to construct a tri-composite split-ring resonator (TC-SRR). The measured results confirm that the proposed technique provides an accurate and inexpensive solution to determine the permittivity of materials

XAI & I: Self-explanatory AI facilitating mutual understanding between AI and human experts

Traditionally, explainable artificial intelligence seeks to provide explanation and interpretability of high-performing black-box models such as deep neural networks. Interpretation of such models remains difficult, because of their high complexity. An alternative method is to instead force a deep-neural network to use human-intelligible features as the basis for its decisions. We tested this approach using the natural category domain of rock types. We compared the performance of a black-box implementation of transfer-learning using Resnet50 to that of a network first trained to predict expert-identified features and then forced to use these features to categorise rock images. The performance of this feature-constrained network was virtually identical to that of the unconstrained network. Further, a partially constrained network forced to condense down to a small number of features that was not trained with expert features did not result in these abstracted features being intelligible; nevertheless, an affine transformation of these features could be found that aligned well with expert-intelligible features. These findings show that making an AI intrinsically intelligible need not be at the cost of performance

An Obscure Case of Hepatic Subcapsular Hematoma

Spontaneous liver bleeding is often reported in preeclampsia. It is otherwise rare and has been linked to gross anatomical lesions and coagulopathy. We report a case of subcapsular hematoma of the liver without any apparent lesion and in the absence of coagulopathy. A 41-year-old male, paraplegic for 16 years, presented to the emergency department 3 days after sudden onset of right upper quadrant and shoulder pain. He had been on vitamins and 5,000 units subcutaneous heparin 12-hourly at the nursing home for the last month. He was in no distress, afebrile, with stable vitals. Physical examination showed a diverting colostomy, tender hepatomegaly and sacral decubiti. A fecal occult blood test was negative. There was spastic paraplegia below the level of T12. Two days after admission, the patient was afebrile and hemodynamically stable. PTT, PT, liver profile, BUN and creatinine were all normal, however his hemoglobin had dropped from 11.3 to 7.6 g/dl. An abdominal CT scan revealed an isolated 9.0 × 1.8 cm subcapsular hematoma. The patient received blood transfusion in the intensive care unit and was discharged 7 days later. In conclusion, spontaneous liver hemorrhage occurs in the nonobstetrical population in the setting of gross anatomical lesions or coagulopathy. This is the first report of an isolated subcapsular liver hematoma

Telomerase Deficiency Predisposes to Heart Failure and Ischemia-Reperfusion Injury

Introduction: Elevated levels of mitochondrial reactive oxygen species (ROS) contribute to the development of numerous cardiovascular diseases. TERT, the catalytic subunit of telomerase, has been shown to translocate to mitochondria to suppress ROS while promoting ATP production. Acute overexpression of TERT increases survival and decreases infarct size in a mouse model of myocardial infarct, while decreased telomerase activity predisposes to mitochondrial defects and heart failure. In the present study, we examined the role of TERT on cardiac structure and function under basal conditions and conditions of acute or prolonged stress in a novel rat model of TERT deficiency.Methods: Cardiac structure and function were evaluated via transthoracic echocardiogram. Langendorff preparations were used to test the effects of acute global ischemia reperfusion injury on cardiac function and infarction. Coronary flow and left ventricular pressure were measured during and after ischemia/reperfusion (I/R). Mitochondrial DNA integrity was measured by PCR and mitochondrial respiration was assessed in isolated mitochondria using an Oxygraph. Angiotensin II infusion was used as an established model of systemic stress.Results: No structural changes (echocardiogram) or coronary flow/left ventricle pressure (isolated hearts) were observed in TERT−/− rats at baseline; however, after I/R, coronary flow was significantly reduced in TERT−/− compared to wild type (WT) rats, while diastolic Left Ventricle Pressure was significantly elevated (n = 6 in each group; p < 0.05) in the TERT−/−. Interestingly, infarct size was less in TERT−/− rats compared to WT rats, while mitochondrial respiratory control index decreased and mitochondrial DNA lesions increased in TERT−/− compared to WT. Angiotensin II treatment did not alter cardiac structure or function; however, it augmented the infarct size significantly more in TERT−/− compared to the WT.Conclusion: Absence of TERT activity increases susceptibility to stress like cardiac injury. These results suggest a critical role of telomerase in chronic heart disease

The T cell differentiation landscape is shaped by tumour mutations in lung cancer

Tumour mutational burden (TMB) predicts immunotherapy outcome in non-small cell lung cancer (NSCLC), consistent with immune recognition of tumour neoantigens. However, persistent antigen exposure is detrimental for T cell function. How TMB affects CD4 and CD8 T cell differentiation in untreated tumours and whether this affects patient outcomes is unknown. Here, we paired high-dimensional flow cytometry, exome, single-cell and bulk RNA sequencing from patients with resected, untreated NSCLC to examine these relationships. TMB was associated with compartment-wide T cell differentiation skewing, characterized by loss of TCF7-expressing progenitor-like CD4 T cells, and an increased abundance of dysfunctional CD8 and CD4 T cell subsets with strong phenotypic and transcriptional similarity to neoantigen-reactive CD8 T cells. A gene signature of redistribution from progenitor-like to dysfunctional states was associated with poor survival in lung and other cancer cohorts. Single-cell characterization of these populations informs potential strategies for therapeutic manipulation in NSCLC

Temporal Dynamics of Interferon Gamma Responses in Children Evaluated for Tuberculosis

BACKGROUND: Development of T-cells based-Interferon gamma (IFNgamma) assays has offered new possibilities for the diagnosis of latent tuberculosis infection (LTBI) and active disease in adults. Few studies have been performed in children, none in France. With reference to the published data on childhood TB epidemiology in the Paris and Ile de France Region, we considered it important to evaluate the performance of IGRA (QuantiFERON TB Gold In Tube(R), QF-TB-IT) in the diagnosis and the follow-up through treatment of LTBI and active TB in a cohort of French children. METHODOLOGY/PRINCIPAL FINDINGS: 131 children were recruited during a prospective and multicentre study (October 2005 and May 2007; Ethical Committee St Louis Hospital, Paris, study number 2005/32). Children were sampled at day 0, 10, 30, 60 (except Healthy Contacts, HC) and 90 for LTBI and HC, and a further day 120, and day 180 for active TB children. Median age was 7.4 years, with 91% of the children BCG vaccinated. LTBI and active TB children undergoing therapy produced significant higher IFNgamma values after 10 days of treatment (p = 0.035). In addition, IFNgamma values were significantly lower at the end of treatment compared to IFNgamma values at day 0, although the number of positive patients was not significantly different between day 0 and end of treatment. CONCLUSIONS/ SIGNIFICANCE: By following quantitative IFNgamma values in each enrolled child with LTBI or active TB and receiving treatment, we were able to detect an increase in the IFNgamma response at day 10 of treatment which might allow the confirmation of a diagnosis. In addition, a decline in IFNgamma values during treatment makes it possible for clinicians to monitor the effect of preventive or curative therapy