Two Dimensional Clustering of Gamma-Ray Bursts using durations and hardness

Gamma-Ray Bursts (GRBs) have been conventionally bifurcated into two distinct categories: ``short'' and ``long'' with durations less than and greater than two seconds respectively. However, there is a lot of literature (although with conflicting results) regarding the existence of a third intermediate class. To investigate this issue, we extend a recent study (arXiv:1612.08235) on classification of GRBs to two dimensions by incorporating the GRB hardness in addition to the observed durations. We carry out this unified analysis on GRB datasets from four detectors, viz. BATSE, RHESSI, Swift (observed and intrinsic frame), and Fermi-GBM. We consider the duration and hardness features in log-scale for each of these datasets and determine the best-fit parameters using Gaussian Mixture Model. This is followed by information theoretic criterion (AIC and BIC) to determine if a three-component fit is favored compared to a two-component one or vice-versa. For BATSE, we find that both AIC and BIC show preference for three components with decisive significance. For Fermi and RHESSI, both AIC and BIC show preference for two components, although the significance is marginal from AIC, but decisive using BIC. For Swift dataset in both the observed and rest frame, we find that three components are favored according to AIC with decisive significance, and two are preferred with BIC with marginal to strong significance.Comment: 13 pages, 10 figures. This is an extension of arXiv:1612.08235 to two-dimension

Predicting Fraud Apps Using Hybrid Learning Approach: A Survey

Each individual in the planet are mobile phone users in fact smart-phone users with android applications. So, due to this attractiveness and well-known concept there will be a hasty growth in mobile technology. And in addition in information mining, mining the required information from a fastidious application is exceptionally troublesome. Consolidating these two ideas of ranking frauds in android market and taking out required information is gone exceptionally tough.The mobile phone Apps has developed at massive speed in some years; as for march 2017, there are nearby 2.8 million Apps at google play and 2.2 Apps at Google Apps store. In addition, there are over 400,000 self-governing app developers all fighting for the attention of the same potential clients. The Google App Store saw 128,000 new business apps alone in 2014 and the mobile gaming category alone has contest to the tune of almost 300,000 apps. Here the major need to make fraud search in Apps is by searching the high ranked applications up to 30-40 which may be ranked high in some time or the applications which are in those high ranked lists should be confirmed but this is not applied for thousands of applications added per day. So, go for wide examination by applying some procedure to every application to judge its ranking. Discovery of ranking fraud for mobile phone applications, require a flawless, fraud less and result that show correct application accordingly provide ranking; where really make it occur by searching fraud of applications. They create fraud of App by ranked high the App by methods using such human water armies and bot farms; where they create fraud by downloading application through different devices and provide fake ratings and reviews. So, extract critical data connecting particular application such as review which was called comments and lots of other information, to mine and place algorithm to identify fakeness in application rank

3D-BIOPRINTING (Application of 3D printer for Organ Fabrication)

Chronic shortage of human organs for transplantation has become more problematic in spite of major development in transplant technologies. In 2009, only 27,996 (18%) of 154,324 patients received organs and 8,863 (25 per day) died while on the waiting list. As of early 2014, approximately 120,000 people in the U.S. were awaiting an organ transplant. The solution to this problem is 3D bio-printing. This technology may provide a unique and new opportunity where we can print 3D organs. It incorporates two technologies, tissue engineering and 3D printing. 3D bioprinting involves dispensing cells onto a biocompatible scaffold using a successive layer-by-layer approach to generate tissue-like three-dimensional structures. It uses instruction in the CAD file for formation of the object, high level computer programming and ability to build highly advanced computer systems, it offers hope for bridging the gap between organ shortage and transplantation needs

Preliminary Screening of Antimicrobial Properties of Few Medicinal Plants

Crude extracts were prepared from the leaves of ten medicinal plants viz., Alpinia galanga, Artabotrys uncinatus, Commelina benghalensis, Costus igneus, Euphorbia cyathopora, Justicia gendarussa, Kalanchoe pinnata, Panicum antidotale, Sauropus androgynous and Hibiscus using methanol as solvent and screened for their antibacterial activity against ten bacterial pathogens. The tested gram positive bacterial strains were Bacillus cerus, Bacillus megaterium, Micrococcus leuteus, Staphylococcus aureus, Streptococcus lactis, and gram negative strains were Pseudomonas aeruginosa, Escherichia coli, Enterobacter aerogenes, Klebsiella pneumoniae and Salmonella typhimurium. Among the ten plants tested, the methanol extracts of Alpinia galanga, Artabotrys uncinatus, Costus igneus and Yellow Hibiscus exhibited higher antibacterial activity when compared to the other plant extracts. These four plant extracts were further used for the phytochemical analysis. Results of the phytochemical analysis indicated the presence of alkaloids, phenolic compounds and flavanoids. The antibacterial activities of the leaves were due to the presence of various secondary metabolite

Comparative Evaluation of the Sealing Ability of Two Different Sealing Agents on the Microgap at the Implant – Abutment Interface following Cyclic Loading: An Invitro study

PURPOSE: The purpose of this invitro study is to comparatively evaluate the sealing ability of two different sealing agent on the microgap at the implant – abutment interface following cyclic loading MATERIALS AND METHODS: Thirty titanium implants with internal connection design were embedded in clear auto polymerising resin. Group I samples consists of ten implants with no sealing agents used, Group II samples consists of ten implants with Cervitec varnish as sealing agent used in implant – abutment interface and Group III samples consists of ten implants with Gapseal as sealing agent at implant – abutment interface and abutment are tightened. Implant – abutment assemblies were tightened at the torque of 35Ncm and microgap at implant – abutment interface was evaluated using scanning electron microscope at mid labial region of buccal aspect of implant. Then, the implant assemblies were mechanically loaded at 1,20,000 cycles with the force of 400N and the frequency of 2Hz. After cyclic loading, all the samples were evaluated for microgap at the implant – abutment interface and the data were tabulated and statistically analysed using paired t-test, one way ANOVA and post hoc tukey test. RESULTS: The mean microgap value for group I (Control) samples before cyclic loading was 2.35μm and after cyclic loading was 4.81μm. For group II (Cervitec varish) samples, the microgap value before cyclic loading was 1.61μm and after cyclic loading was 2.62μm. For group III (Gapseal) samples, the microgap values before cyclic loading was 0.71μm and after cyclic loading was 1.50μm. Paired ‘t’-test, One way ANOVA and post hoc tukey showed statistically significant difference between three groups. On multiple comparisons, the mean microgap difference value exhibited with Group III test samples is lesser than that of Group II test samples and on statistical analysis, experimental groups were found to be statistically insignificant with p value of 0.733 (p value < 0.05; significant). CONCLUSION: Within the limitation of the study, application of Gapseal and Cervitec varnish reduced the dimension of microgap at implant – abutment interface. On comparison between Gapseal and Cervitec varnish, Gapseal reduces the microgap more than that of Cervitec varnish. The microgap obtained by all the three groups was found to be within the clinically acceptable limit (10μm)

A prospective, randomized, blinded, comparative study on the effect of “liberal Vs. restrictive” fluid protocol on post-operative nausea vomiting and discharge criteria in patients undergoing puerperal sterilization under GA as day care surgery

BACKGROUND: Adequate control of postoperative nausea, vomiting, pain, dizziness and thirst and early return to normal activity are important anesthetic goals in the context of ambulatory surgery. The aim of this study was to compare the effects of “liberal vs. restrictive” fluid protocol on post-operative nausea vomiting and discharge criteria in patients undergoing puerperal sterilization under GA as day care surgery. MATERIALS AND METHODS: One hundred and two ASA PS 1 and 2 patients aged between 18 and 40 years, undergoing puerperal sterilization under GA as day care procedure and meeting inclusion criteria were drafted into the study. The patients were randomly assigned to one of two groups, each having 51 patients. Pre-operatively, Group R (Restrictive fluid protocol) patients received 2ml/kg of Ringer Lactate over 20 minutes. Group L (Liberal fluid protocol) patients received 15 ml/kg of Ringer Lactate. A standard general anesthetic technique was used. Adverse postoperative outcomes were assessed at 2,6,12 and 24 hours post-operatively by an anaesthesiologist blinded to the study. RESULTS: The incidence of Post –Operative Nausea and Vomiting (PONV), Pain, Thirst is significantly reduced in liberal fluid group group (PONV 2, 6 , 12 hours “p” value = 0.0005 : Pain “p” value = 0.0005 : Thirst “p” value = 0.015) when compared to restrictive fluid group .The patients who received liberal fluid achieved discharge criteria earlier than those who received restrictive fluid (“p” value = 0.0005). No significant difference is found for headache, dizziness, drowsiness, fatigue, post-operative ileus, Post-operative Exercise capacity and mobilization between both the groups. CONCLUSION: Preoperative hydration effectively reduced PONV in patients presenting for ambulatory surgery. Hence I conclude that liberal fluid therapy is an inexpensive and safe therapy for reducing post-operative nausea and vomiting

A SCIENTIFIC REVIEW OF MOOLAM (ANO RECTAL DISEASES)-YUGIS VERSION

Worldwide, the overall prevalence of an ano rectal disease in the general population is estimated to be 4.4%. The faulty dietary pattern and life style , hereditary factors are important etiological factors of this disease. As per saint Yugi  Moolam is classified as 21 types based on clinical symptoms and size, shape, colour of the pile mass which includes some of the ano-rectal diseases. The diet and deeds which influences the vital humors Vatham  (Intestinal peristaltic movement ) and Pitham (metabolism and absorption) of food stuffs are said to be major causative factors of this disease. As per Yugis version the following ano rectal diseases under Moola noi have been categorized as, Neer moolam (Inflammatory bowel disease), Aazhi moolam (strangulated haemorrhoids), Sittru moolam (adenomatous colorectal polyps), Varal moolam (colorectal non- neoplastic polyps), Seezh moolam (kaposis sarcoma), Silaethuma moolam (anal warts condyloma), Thondha moolam (rectal cancer), Vinai moolam (irritable bowel syndrome), Powthira moolam (anal fistula), Kutha moolam (rectal prolapse), Ratha moolam (internal haemorrhoids 1st degree -bleeding piles), Mega moolam (gonococcal proctitis), Vaatha moolam (interno-external hemorrhoids), Pitha moolam (prolapsed haemorrhoids), Surukku moolam (anal stenosis), Mulai moolam (sentinel pile), Savvu moolam (perianal tuberclosis). This paper focuses the scientific basis of etiology and classification of Moolam by saint Yugi

Laboratory Profile of Adult Hemoglobinopathies Picked Up During Routine Health Check in a Tertiary Care Hospital from South India

Background and aim: Hemoglobin (Hb) variants can clinically range from being completely asymptomatic to frequent requirement of transfusions. Some individuals may become aware of a variant only when a complete blood count (CBC), hemoglobin analysis or genetic testing is done for a different reason. These individuals are typically heterozygous for an autosomal recessive variant. A study was conducted to find out the different types of hemoglobinopathies in adults presenting to a tertiary care hospital for routine health check and its geographic distribution. Objective: 1) To find out the severity of anemia associated with different hemoglobinopathies. 2) To find the relevance of glycated hemoglobin (HbA1c) in the presence of various hemoglobinopathies. Methods: A retrospective cross-sectional observational study was done in 111 consecutive patients who were found to have hemoglobinopathies during routine health checks in a tertiary care hospital in South India from 2013 to 2021. Results: One hundred eleven patients were found to have abnormality in Hb electrophoresis and there was a male predominance (69 patients, 62.2%). Majority of patients with beta-thalassemia (28 patients, 63.6%) were from West Bengal. Both HbE trait (17 patients, 65.4%) and homozygous HbE (23 patients, 62.2%) were from Assam. There was statistically significant distribution (p value 0.0001). HbA1c detected Hb variant in those with HbE disease. Conclusion: Hemoglobinopathies constitute a huge hereditary burden and a serious healthcare concern in India. Hence, it is the need of the hour to pick up such asymptomatic cases and provide appropriate premarital and prenatal counseling. Also, it is essential to devise strategies other than routine HbA1c testing to guide blood sugar control

Evan’s syndrome secondary to COVID-19 infection

Wide range of autoimmune diseases are known to occur following SARS-CoV-2 infection. There are very few case reports of Evan’s syndrome secondary to COVID-19. We hereby report a case of Evan’s syndrome secondary to COVID-19 infection and discuss its management