29 research outputs found
SzelektĂv szintĂ©zismĂłdszerek kifejlesztĂ©se vizes közegben átmenetifĂ©m-komplexek jelenlĂ©tĂ©ben = Development of selective synthetic methods in aqueous medium in the presence os transition metal complexes
KutatĂłmunkánkat krĂłm(II) komplexek szelektĂv szintĂ©zisreakciĂłinak fejlesztĂ©sĂ©n vĂ©geztĂĽk. Kidolgoztuk a Nozaki-Hiyama reakciĂł szĂ©n-szĂ©n kötĂ©sek enantioszelektĂv kialakĂtására alkalmas mĂłdszerĂ©t karbonil- Ă©s halogĂ©nszármazĂ©kok kapcsolásában, krĂłm(II) komplexek jelenlĂ©tĂ©ben. Tanulmányoztuk szĂ©nhidrátszármazĂ©kok anomer centrumának reaktivitását CrIIEDTA komplex jelenlĂ©tĂ©ben, semleges-vizes közegben Ă©s Ăşj mĂłdszereket dolgoztunk ki glikálok Ă©s C-glikozidok előállĂtására. TermĂ©szetes aminosavak krĂłm(II) komplexeinek királis informáciĂłját aminok enantioszelektĂv szintĂ©zisĂ©re alkalmaztuk. Tanulmányoztuk az enantioszelektĂv autokatalĂzis törvĂ©nyszerűsĂ©geit, empirikus összefĂĽggĂ©st dolgoztunk ki a királis erĹ‘sĂtĂ©s jellemzĂ©sĂ©re. | Selective synthetic reactions could be developed in our research work in the present of chromium(II) complexes. The Nozaki-Hiyama reaction could be developed for enantioselective carbon-carbon coupling in the reactions of carbonyl- and halogen derivatives using chromium(II) complexes. Reactivity of the anomeric centre of carbohydrate derivatives was investigated with CrIIEDTA complex in neutral aqueous medium and new methods could be developed for preparation of glycals and C-glycosides. Amino acid induced enantioselective amine synthesis could be developed in the presence of Cr(II) in aqueous medium. The principles of the enantioselective autocatalytic reactions could be investigated and empirical relation proposed for the chiral amplification
Reactivity of per-O-acetylated thioglycosides and glycosyl sulfones toward chromium(II) complexes in aqueous medium
Isotope chirality and asymmetric autocatalysis: a possible entry to biological chirality
Stochastic and empirical models of the absolute asymmetric synthesis by the Soai-autocatalysis
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