137 research outputs found
Publish/Subscribe Communication for Crowd-sourcing Based Smart City Applications
Collecting data and monitoring our environment give the basis for smart city applications which are getting popular today. However, the traditional approach to deploy a sensing and monitoring infrastructure is usually expensive and not always practical. Mobile crowd-sourcing can open new ways for data collection and smart city services. In this case, mobile devices with their built-in sensors and their owners are used to monitor the environment. For instance, the timetable of a smart travel planner service can be updated in real-time based on the continuously monitored time gap by passengers between consecutive buses on a public transportation route. This requires a common communication model facilitating crowd-sourced data collection. In this paper, we overview the design considerations of crowd-sourcing based smart city applications, propose data collection via using the publish/subscribe communication model and investigate the possible use of the Extensible Messaging and Presence Protocol (XMPP) for such applications
A Publish-Subscribe Scheme Based Open Architecture for Crowd-Sourcing
Participatory sensing, when a crowd of users collaborate to collect useful information, based applications are getting popular these days thanks to the proliferation of powerful mobile devices. The built-in sensors of smartphones offer an easy and handy way to monitor the environment and collect data which can serve as the basis of smart applications. However, the quick and flexible development and deployment of these applications call for a unifying open architecture. In this paper we propose a publish-subscribe based open participatory sensing architecture
Classification of Hungarian medieval silver coins using x-ray fluorescent spectroscopy and multivariate data analysis
A set of silver coins from the collection of DĂ©ri Museum Debrecen (Hungary) was examined by X-ray
fluorescent elemental analysis with the aim to assign the coins to different groups with the best possible precision
based on the acquired chemical information and to build models, which arrange the coins according to their
historical periods.
Results: Principal component analysis, linear discriminant analysis, partial least squares discriminant analysis,
classification and regression trees and multivariate curve resolution with alternating least squares were applied to
reveal dominant pattern in the data and classify the coins into several groups. We also identified those chemical
components, which are present in small percentages, but are useful for the classification of the coins. With the
coins divided into two groups according to adequate historical periods, we have obtained a correct classification
(76-78%) based on the chemical compositions.
Conclusions: X-ray fluorescent elemental analysis together with multivariate data analysis methods is suitable to
group medieval coins according to historical periods.
Keywords: X-ray fluorescence spectroscopy, Multivariate techniques, Coin, Silver, Middle age
Model of spatial differentation of temperature in Kolozsvár (Románia)
Összefoglalás - A cikk Kolozsvár területének höháztartás-modelljét mutatja be. A szerzők a különböző városi
felszĂnek (beton, aszfalt, vĂz- Ă©s zöldterĂĽlet) eltĂ©rĹ‘ termikus tulajdonságait alapul vĂ©ve. a nap nĂ©gy jellegzetes
idöpillanatjának ábrázolására vállalkoztak. A modell megszerkesztésére a végesdifferencia módszerét használták.
Mindez ideális meteorológiai körülményeket, egy hidegfront elvonulása utáni nyári napot feltételez. Ilyen ideális
körülmények voltak 1997. június 6-án, amikorra a tanulmány vonatkozik. A modell szerint napközben a város
leghidegebb felszĂneit a vĂzfolyás Ă©s azöldterĂĽletek kĂ©pezik. Ezzel szemben a legmagasabb hĹ‘mĂ©rsĂ©kletű tĂ©rsĂ©geket a
beton- Ă©s az aszfaltfelszĂnekjelentik. A legnagyobb hĹ‘mĂ©rsĂ©kletű eltĂ©rĂ©sek este Ă©s Ă©jszakamĂ©rhetök.
Summary - The structure of urban area may give some different effects on the surface radiation the heat budget and
also the heat island phenomenon. The aim of the paper is to study how the urban climate is influenced by different
surfaces which characterise the city area. In order to receive a more comprehensive understanding of the thermal
patterns in and around urban areas in a themperate climate, the present study was carried out in a different urban areas
(e.g. green and water surfaces, streets). Important obj ectures are:
- to study if the diversified size of the multivarious urban influences the magnitude of the temperature difference
between the different style of built-up area;
- to study in what way the density and the structure of the built-up area respectively influences temperature pattern;
-to study the alternation of upwarming and cooling rate in the green and built-up area and its dependence on changes in
cloud cover.
The city of Kolozsvár (Cluj, Romania) has been chosen as study area. The study is caried out with the help of physical
model using computer simulations
Nonlinear Normal Modes of a Piecewise Linear Continuous Structure with a Regular State
In this paper, the dynamic behaviour of a family of piecewise linear structures, namely the vibration of beams on block-and-tackle suspension system is analysed. The regularity of the vibration modes in one of the linear states induces non-harmonic, yet periodic free vibration modes. The periodicity constraint of the continuous structure is formulated using modal analysis in the regular state. The required number of modes in the finite modal analysis is specified so that the numerical damping caused by the omitted modes does not change the periodic or non-periodic nature of the free vibration of the continuous structure. It is shown, that the application of five excess passive modes allows to draw conclusions about the behaviour of the continuous structure. The periodic behaviour depends on the number and position of the suspension points and the number of the active vibration modes. Analysis of the limits of the periodic behaviour reveals that suspension points close to the middle of the beam, or first few active vibration modes result in periodic vibration of the nonlinear system
Measurements of a Real-time Transit Feed Service Architecture for Mobile Participatory Sensing
Abstract—We spend a substantial part of our time with
traveling, in crowded cities usually taking public transportation.
It is important, making travel planning easier, to have accurate
information about vehicle arrival times at the stops. Most of
the public transport operators make their timetables freely
available either on the web or in some special format, like
GTFS (General Transit Feed Specification). However, they contain
static information only, not reflecting the actual traffic conditions.
Mobile participatory sensing can help extend the basic service
with real-time updates letting the crowd collect the required data.
With this respect we believe that such participatory sensing based
application must offer a day zero service following incremental
service extension. In this paper, we discuss how to realize real-time
refinements to static GTFS data based on mobile participatory
sensing. We show how this service can be implemented by
an XMPP (Extensible Messaging and Presence Protocol) based
mobile participatory sensing architecture and we evaluate its
performance
Protein foszfatázok szerepe az endoteliális nitrogén-monoxid szintáz és az endotél barrier funkció szabályozásában
Az endoteliális nitrogĂ©n monoxid szintáz (eNOS) számos kardiovaszkuláris funkciĂł szabályozásában fontos szerepet játszik. Az eNOS aktivitásának szabályozásában a Thr495 oldalláncon törtĂ©nĹ‘ gátlĂł foszforiláciĂł kitĂĽntetett szereppel bĂr. Munkánk során kĂĽlönbözĹ‘ biokĂ©miai Ă©s molekuláris biolĂłgiai technikák alkalmazásával kimutattuk, hogy a miozin foszfatáz (MP) holoenzim, amely egy protein foszfatáz-1 (PP1c) katalitikus Ă©s egy MP regulátor alegysĂ©gbĹ‘l (MYPT1) áll, az eNOSpT495 oldalláncot defoszforilállĂł foszfatáz. Foszfatáz gátlĂłszerek alkalmazása csökkentette a NO kĂ©pzĹ‘dĂ©st valamint az endotĂ©l barrier funkciĂłt, amely az erek homeosztázisának fenntartása szempontjábĂłl kulcsfontosságĂş. Ezzel ellentĂ©tben, az (-)-epigallokatekin-3-gallát (EGCG) kezelĂ©s protein kináz A (PKA) által mediált protein foszfatáz 2A (PP2A) aktiváciĂłt eredmĂ©nyezett. Ennek hatására növekedett a MP aktivitása Ă©s csökkent az eNOSpThr495, valamint a 20 kDa molekulatömegű miozin II könnyűláncot (MLC20) a pThr18/pSer19 foszforiláciĂłs szintje, amely az endotĂ©l sejtek kontraktilis apparátusának relaxáciĂłját idĂ©zte elĹ‘. Az endotĂ©l sejtek barrier funkciĂłjának elvesztĂ©se az erek permeabilitásának növekedĂ©sĂ©hez vezet, amely gyakran sĂşlyos következmĂ©nyekkel jár. Kimutattuk, hogy a kĂ©t barrier protektĂv vegyĂĽlet, az adenozin (Ado) Ă©s ATPÎłS kĂĽlönbözĹ‘ jelátviteli Ăştvonalakon fejtik ki hatásukat a HLMVEC sejteken. Az ATPÎłS a P2Y4 Ă©s P2Y12 receptorok közvetĂtĂ©sĂ©vel cAMP fĂĽggetlen Ăştvonalon PKA aktiváciĂłt idĂ©z elĹ‘, amely a ppMLC20 foszforiláciĂłs szintjĂ©nek csökkenĂ©sĂ©hez vezet. Ezzel szemben az Ado indukálta endotĂ©l barrier funkciĂł növekedĂ©sĂ©hez a PKA Ă©s EPAC1 koordinált cAMP fĂĽggĹ‘ aktiváciĂłja szĂĽksĂ©ges. EredmĂ©nyeink kulcsfontosságĂş endotĂ©l fehĂ©rjĂ©k receptor-mediált foszforiláciĂłs-defoszforiláciĂłs folyamataira, valamint ezek szabályozásában szerepet játszĂł kinázok, foszfatázok Ă©s jelátviteli Ăştvonalak szerepĂ©re derĂtenek fĂ©nyt.The importance of eNOS to cardiovascular homeostasis has been well established. A major regulator of the activity of eNOS is post-translational phosphorylation and in particular the inhibitory phosphorylation at Thr495. Using various biochemical and molecular biological techniques we have demonstrated that the myosin phosphatase (MP) holoenzyme, comprised of protein phosphatase-1 catalytic subunit (PP1c) and the MP target subunit-1 (MYPT1), is a bona fide eNOSpThr495 phosphatase. Furthermore, phosphatase inhibitors were shown to suppress NO production and decrease barrier function, both of which are important functions in ECs. Epigallocatechin-3-gallate (EGCG) treatment induced protein kinase A (PKA) -dependent activation of protein phosphatase-2A (PP2A) which increased MP activity. Activated MP dephosphorylated both eNOSpThr495 and the 20 kDa myosin II light chains at Thr18/Ser19 (ppMLC20) which resulted in relaxation of ECs. Loss of EC barrier integrity results in increased vascular permeability, which often has severe consequences including the flooding of alveolar space that occurs in pneumonia. We have shown that adenosine (Ado) and ATPÎłS, two EC barrier protective agents, exert their profound barrier protecting effects on HLMVEC via distinct signaling mechanisms. ATPÎłS induced P2Y4 and P2Y12 mediated cAMP independent PKA activation, resulting in MP activation and ppMLC20 dephosphorylation. However, Ado-induced strengthening of the HLMVEC barrier required the coordinated activation of PKA and EPAC1 in cAMP-dependent manner. In summary our studies shed light on the receptor-mediated phosphorylation-dephosphorylation of key endothelial proteins and identified kinases and phosphatases as well as the signaling pathways implicated in these modifications
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