Survey of urologists on clients’ demand for screening for prostate cancer in Nigeria

Objective: The aim of this article is to document the experience of urologists on clients’ demand for prostate cancer screening among Nigerians.Materials and Methods: The study is a cross-sectional evaluation of the urologists that attended the Fourteenth Annual Meeting and the Scientific Conference of the Nigerian Association of Urological Surgeons. A structured questionnaire was used to assess the estimated workload of the respondents, with reference to prostate cancer management, the stage proportion at the time of diagnosis, and the proportion of patients requesting for CaP screening. The data was analyzed using the SPSS version 15 statistical software.Results: Twenty-two respondents completed and returned the questionnaire and formed the basis of further analysis. About 76.9% of the consultant urologists were also lecturers in their respective universities. They were all actively practicing and a majority of them, 76.9%, had up to 10 years experience as practicing urologists. The majority of the respondents managed between one and fifteen new patients with CaP every month, with 36.4% of them managing more than 15 new patients on an average every month. About 95.4% of all the patients seen by the respondents were diagnosed with advanced stages of the disease, while the remaining ones were incidental findings. About one half of the respondents attended to clients seeking for advice on CaP ‘often’ or ‘very often,’ while 40.9% attended to them ‘occasionally,’ with a mean of 4.67 clients seeking advice per month. The majority of respondents, 20 (22); 90.9%, were ‘not aware’ of any national guideline on CaP screening.Conclusions: A majority of practitioners affirmed that patients with prostate cancer present late. The mean number of patients requesting for screening for prostate cancer per month, per respondent, for CaP, is still low. It is the authors’ belief that the trend may not change until there is an appropriate effort at health education, to enlighten the populace

Optimisation of Spray Deposited SnO2 Thin Film for Solar Cell Fabrication

The use of conducting tin-oxide (SnO2 ) films for fabrication of  solar cell is becoming increasingly important because of reasonably high efficiency and ease in fabrication. The role of the thin-oxide film is very critical for high efficiency. Resistivity, thickness and transmittance of the film should be of correct order. The most favourable conditions for fabrication of SnO2 layer with low resistivity and high transmittance is reported in this paper. Effect of doping and annealing on these properties has also been studied. It is observed that doping with antimony gives better layer with sheet resistivity of approximately 60 ohm/square (Ω/◊) and transmittance of the order of 80%. Annealing in air and vacuum shows a decrease in resistivity while it has negligible effect on its transmittance.Attempts have also been made to fabricate Sn2/Si solar cell with the present set up, and efforts are being made to optimize its performance

Finding 2-Edge and 2-Vertex Strongly Connected Components in Quadratic Time

We present faster algorithms for computing the 2-edge and 2-vertex strongly connected components of a directed graph, which are straightforward generalizations of strongly connected components. While in undirected graphs the 2-edge and 2-vertex connected components can be found in linear time, in directed graphs only rather simple $O(m n)$-time algorithms were known. We use a hierarchical sparsification technique to obtain algorithms that run in time $O(n^2)$. For 2-edge strongly connected components our algorithm gives the first running time improvement in 20 years. Additionally we present an $O(m^2 / \log{n})$-time algorithm for 2-edge strongly connected components, and thus improve over the $O(m n)$ running time also when $m = O(n)$. Our approach extends to k-edge and k-vertex strongly connected components for any constant k with a running time of $O(n^2 \log^2 n)$ for edges and $O(n^3)$ for vertices

Forming of simple components of silicon carbide, Silicon nitride and silicon by slip casting methods

The slip casting studies on well optimised slips of Sic, Si3N 4 and silicon have been applied to fabricate some components with complicated shapes eg. after burner catalytic ignitor housings, super charger stator rings etc. The green densities of slip cast bodies of Sic, Si3N4 and silicon slips ranges from 50 to 60 of theoretical value, indicating that good compacts can be obtained by the slip casting procedure by using these optimised slips

The Best I Can Be: How Self-Accountability Impacts Product Choice in Technology-Mediated Environments

This is the author accepted manuscript. The final version is available from Wiley via the DOI in this recordTechnology-mediated environments are important not only as the location for an increasing proportion of purchases, but also as an even more pervasive part of the purchase journey. While most research into online consumer behavior focuses on attitudes as an antecedent of product choice, this article focuses on an important but hardly explored variable that may be impacted by technology-mediated environments: self-accountability. Laboratory experiments suggest that self-accountability may influence online purchases, but this has not been confirmed in field studies. Furthermore, although this prior work suggests that self-accountability may impact product choice through the elicitation of guilt, the role of positive emotions has not been explored. Using two surveys with online retailers, this paper (a) shows that in a technology-mediated environment, self-accountability influences product choice; (b) proposes and confirms a complementary route for this effect through pride that is stronger than that through guilt; and (c) evidences the relationship between self-accountability and perceived consumer effectiveness. These results show a clear opportunity for digital marketers to encourage self-accountability, to thereby elicit pride and not just guilt, and hence to impact consumer decision making in technology-mediated environments, particularly when choices have sustainability implications

INSIGHTS ON DRUG TARGETING OF TOXOPLASMA GONDII HOST INVASION PROTEINS: A REVIEW

Toxoplasma gondii is an obligate intracellular parasite that infects homoeothermic animals. It is also the major cause of retinochoroiditis in humans.Drugs targeting T. gondii proteins involved in the establishment of host-pathogen interactions is well documented to be an efficient way to combatthe infections. Basically, parasitic invasion of T. gondii occurs by the sequential secretion of apical membrane antigen 1 and rhoptry neck proteins onthe parasite and host cell surfaces, respectively. These proteins operate synergistically and form the moving junction (MJ) complex, thereby, enablingattachment and penetration of the parasite into the host cell. Better understanding of molecular interactions of these proteins is essential to develophighly efficient therapeutic modalities. Hence, by this review it is intended to update the current status of rhoptry and other MJ complex proteins asideal candidates for targeting T. gondii.Keywords: Toxoplasma gondii, Rhoptry proteins, Moving junction complex, Toxoplasmosis

On the use of Li isotopes as a proxy for water–rock interaction in fractured crystalline rocks: A case study from the Gotthard rail base tunnel

We present Li isotope measurements of groundwater samples collected during drilling of the 57 km long Gotthard rail base tunnel in Switzerland, to explore the use of Li isotope measurements for tracking water–rock interactions in fractured crystalline rocks at temperatures of up to 43 °C. The 17 groundwater samples originate from water-conducting fractures within two specific crystalline rock units, which are characterized by a similar rock mineralogy, but significantly different fluid composition. In particular, the aqueous Li concentrations observed in samples from the two units vary from 1–4 mg/L to 0.01–0.02 mg/L. Whereas δ7Li values from the unit with high Li concentrations are basically constant (δ7Li = 8.5–9.1‰), prominent variations are recorded for the samples from the unit with low Li concentrations (δ7Li = 10–41‰). This observation demonstrates that Li isotope fractionation can be highly sensitive to aqueous Li concentrations. Moreover, δ7Li values from the unit with low Li concentrations correlate well with reaction progress parameters such as pH and [Li]/[Na] ratios, suggesting that δ7Li values are mainly controlled by the residence time of the fracture groundwater. Consequently, 1D reactive transport modeling was performed to simulate mineral reactions and associated Li isotope fractionation along a water-conducting fracture system using the code TOUGHREACT. Modeling results confirm the residence time hypothesis and demonstrate that the absence of δ7Li variation at high Li concentrations can be well explained by limitation of the amount of Li that is incorporated into secondary minerals. Modeling results also suggest that Li uptake by kaolinite forms the key process to cause Li isotope fractionation in the investigated alkaline system (pH >9), and that under slow flow conditions (<10 m/year), this process is associated with a very large Li isotope fractionation factor (ε ≈ −50‰). Moreover, our simulations demonstrate that for simple and well-defined systems with known residence times and low Li concentrations, δ7Li values may help to quantify mineral reaction rates if more thermodynamic data about the temperature-dependent incorporation of Li in secondary minerals as well as corresponding fractionation factors become available in the future. In conclusion, δ7Li values may be a powerful tool to track water–rock interaction in fractured crystalline rocks at temperature higher than those at the Earth’s surface, although their use is restricted to low Li concentrations and well defined flow systems

Novel battery thermal management via scalable dew-point evaporative cooling

Thermal management is critical to safety, stability, and durability of battery energy storage systems. Existing passive and active air cooling are not competent when the cooling performance, energy efficiency and cost of the thermal management system are drawing concurrent concerns. Here we propose dew-point evaporative cooling as a novel active air-cooling approach for large battery systems. Its capability of cooling the air towards its dew-point temperature with simple working principle and great electrical efficiency offers an ideal solution. Therefore, a scalable dew-point evaporative cooling technology was developed, and a large-scale cooler was constructed which could deliver 2.9–6.7 kW cooling capacity with 8.9–28.9 coefficient of performance (COP). To demonstrate its performance for battery thermal management, we took a 20 Ah lithium iron phosphate (LFP) prismatic pouch cells for a case study whose complex dynamic electrochemical and thermal responses were investigated via lock-in thermography experiments and electrochemical-thermal modeling. The potential of dew-point evaporative cooling for battery cooling was explored via the multi-physics coupling of battery and cooler models. This study elucidates that dew-point evaporative cooling can efficiently cool a battery by 3.0–13.6 °C lower than the cases with only forced convection, and control the battery operating temperature within an ideal operating range of 20–40 °C