Effects of water level fluctuation on thermal stratification in a typical tributary bay of Three Gorges Reservoir, China

Xiangxi River is a typical tributary of Three Gorges Reservoir (TGR) in China. Based on field observations in 2010, thermal stratification was significant in most months of the year. Through field data analysis and numerical simulations, the seasonal and spatial variation of thermal stratification as related to the impact of the operation of TGR were investigated. Thermal stratification was most pronounced from April to September in the Xiangxi River tributary. Air temperature (AT) and water level (WL) were the two dominant variables impacting thermal stratification. AT affected the surface water temperature promoting the formation of thermal stratification, and high WLs in TGR deepened the thermocline depth and thermocline bottom depth. These results provide a preliminary description of the seasonal variation and spatial distribution of thermal stratification, which is important for better understanding how thermal stratification affects algae blooms in Xiangxi River

Effects of Water Level Fluctuation on Thermal Stratification in a Typical Tributary Bay of Three Gorges Reservoir, China

Xiangxi River is a typical tributary of Three Gorges Reservoir (TGR) in China. Based on field observations in 2010, thermal stratification was significant in most months of the year. Through field data analysis and numerical simulations, the seasonal and spatial variation of thermal stratification as related to the impact of the operation of TGR were investigated. Thermal stratification was most pronounced from April to September in the Xiangxi River tributary. Air temperature (AT) and water level (WL) were the two dominant variables impacting thermal stratification. AT affected the surface water temperature promoting the formation of thermal stratification, and high WLs in TGR deepened the thermocline depth and thermocline bottom depth. These results provide a preliminary description of the seasonal variation and spatial distribution of thermal stratification, which is important for better understanding how thermal stratification affects algae blooms in Xiangxi River

Thermal Stratification and its Relationship With Water Quality in the Typical Tributary Bay of the Three Gorges Reservoir

The effect of thermal stratification and its relationship with water quality was researched by field observation in this study. Through assessing the degree of thermal stratification by calculating the dimensionless parameter of thermal resistance to mixing (RTRM) indices from 2008 to 2010, it indicated that the water body of Xiangxi River was stratified strongly in the summer months. The analysis of the degree of thermal stratification with both the meteorological and hydrodynamic factors showed thermal stratification intensity was more sensitive to meteorological factors in Xiangxi River. Through the analysis of the relationship between thermal stratification and water quality, the results indicated that the concentration of Chlorophyll a was higher in the epilimnion affected by the thermal stratification, which could cause algal bloom. The results may further help to evaluate the thermal stratification role in eutrophication process and algal bloom formation in Xiangxi River

Additional file 1: of Housing type and myopia: the mediating role of parental myopia

The National Eye Care Study Questionnaire (Parental Questionnaire for Grade 1–3 Children). (DOC 67 kb

Lipopolysaccharides may aggravate apoptosis through accumulation of autophagosomes in alveolar macrophages of human silicosis

<p>Silica dust mainly attacks alveolar macrophages (AMs) and increases the apoptosis of AMs in silicosis patients. However, it is still unclear whether autophagy is affected. Autophagy mainly has defensive functions in response to stress, contributing to cell survival in adverse conditions, and conversely it has also been implicated in cell death. Lipopolysaccharide (LPS) induces autophagy and apoptosis in macrophages. The role of LPS in autophagy and apoptosis in AMs of silicosis patients is unknown. In this study, we collected AMs from 53 male workers exposed to silica and divided them into an observer (control) group, and stage I, II and III patient groups. We found increased levels of LC3B, SQSTM1/p62 and BECN1，whereas the phosphorylation of MTOR，and levels of LAMP2, TLR4, MYD88, TICAM1, as well as the number of lysosomes decreased with the development of silicosis. LPS stimulation triggered autophagy and increased levels of SQSTM1 in AMs. The autophagy inhibitor, 3-methyladenine (3MA), inhibited LPS-induced apoptosis in the AMs of silicosis patients. Moreover, 3MA reversed the LPS-induced decrease in BCL2 and the increase in BAX and CASP3 levels in AMs. These results suggest that autophagosomes accumulate in AMs during silicosis progression. LPS can induce the formation of autophagosomes through a TLR4-dependent pathway, and LPS may exacerbate the apoptosis in AMs. Blockade of the formation of autophagosomes may inhibit LPS-induced apoptosis via the intrinsic apoptotic pathway in AMs. These findings describe novel mechanisms that may lead to new preventive and therapeutic strategies for pulmonary fibrosis.</p