Basal energy expenditure and diet-induced modifications to thermogenesis in short bowel syndrome

Background & aim: the influence of food intake on diet-induced thermogenesis, in the absence of parenteral nutrition, has not been assessed in short bowel syndrome (SBS) patients. We studied basal energy expenditure (BEE) and diet-induced thermogenesis in SBS patients (n = 8) and paired healthy adult volunteer controls (n = 8).Methods: Energy expenditure was measured by indirect calorimetry (IC) before and after control diet intake. All study participants received oral control diet randomly given in 3 doses (A = 1.0, B = 1.5 and C = 2.0) x 1/6 of BEE calories. Bioelectric impedance was assessed. Pairing criteria for controls were: age, sex, body mass index.Results: No significant differences were found between SBS and paired healthy control groups in relation to absolute BEE (P = 0.146) and when it was adjusted for body mass index, lean and fat body mass (P = 0.861, 0.208 and 0.574, respectively). All diets promoted thermogenesis in both groups. the interaction between the control diet (A, B and C) and SBS and healthy control groups for diet induced thermogenesis presented a significant difference (P = 0.026). When comparing groups (SBS vs healthy controls) in relation to the control diet (B and C) we observed: P = 0.030 and 0.004, respectively.Conclusion: in patients with SBS it was observed that: (1) BEE measured by IC in absolute values or adjusted by lean body mass is similar to healthy control group; (2) Diet-induced thermogenesis was lower than the healthy control group for higher caloric diets (B and C). (C) 2004 Elsevier B.V. All rights reserved.Univ São Paulo, Fac Med, Dept Gastroenterol, Metanutri Lab LIM 35, BR-01323001 São Paulo, BrazilFed Univ Parana, Hosp Clin, Nutr & Diet Serv, Curitiba, Parana, BrazilUniv São Paulo, Fac Med, Hosp Clin, Nutr & Diet Serv, São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Dept Pediat, Nutr & Metab Sector, São Paulo, BrazilUniv São Paulo, Fac Med, Dept Endocrinol, São Paulo, BrazilUniversidade Federal de São Paulo, Escola Paulista Med, Dept Pediat, Nutr & Metab Sector, São Paulo, BrazilWeb of Scienc

O papel da citologia no diagnóstico das neoplasias músculo-esqueléticas: revisão sistemática The role of cytology in the diagnosis of musculoskeletal neoplasms: systematic review

Os autores revisaram sistematicamente a literatura da última década sobre o papel ocupado pela citologia na avaliação das neoplasias músculo-esqueléticas e sua precisão diagnóstica. Foi realizada uma consulta nas bases de dados PubMed, MEDLINE, LILACS e SciELO, que utilizassem a citologia no diagnóstico das lesões músculo-esqueléticas . Foram utilizados limites para os idiomas inglês, espanhol e português. e artigos publicados a partir de 2000. Foram resgatados 757 artigos, dos quais 24 foram selecionados com a aplicação dos critérios de inclusão e exclusão. Concluiu-se que apesar de promissora na avaliação das lesões músculo-esqueléticas, a citologia obtida por punção por agulha fina é menos precisa e confiável do que a avaliação histológica na avaliação dessas lesões.<br>The authors systematically reviewed the literature of the last decade on the role of cytology in theevaluation of musculoskeletal neoplasms, and its diagnostic accuracy. A search was carried out on the databases PubMed, MEDLINE, LILACS and SciELO, selecting articles in which cytology was used in the diagnosis of musculoskeletal neoplasms. Limits(Boolean operators?) were used for English, Spanish and Portuguese, and only articles published since2000 were selected. 757 articles were retrieved, 24 of which were selected based on criteria of inclusion and exclusion. It was concluded that although promising in the assessment of musculoskeletal neoplasms, cytology obtained by fine needle aspiration is less accurate and reliable than histological evaluation of such lesions