21 research outputs found

    Gendered Self-Views across 62 Countries: A Test of Competing Models

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    Social role theory posits that binary gender gaps in agency and communion should be larger in less egalitarian countries, reflecting these countries’ more pronounced sex-based power divisions. Conversely, evolutionary and self-construal theorists suggest that gender gaps in agency and communion should be larger in more egalitarian countries, reflecting the greater autonomy support and flexible self-construction processes present in these countries. Using data from 62 countries (N = 28,640), we examine binary gender gaps in agentic and communal self-views as a function of country-level objective gender equality (the Global Gender Gap Index) and subjective distributions of social power (the Power Distance Index). Findings show that in more egalitarian countries, gender gaps in agency are smaller and gender gaps in communality are larger. These patterns are driven primarily by cross-country differences in men’s self-views and by the Power Distance Index (PDI) more robustly than the Global Gender Gap Index (GGGI). We consider possible causes and implications of these findings

    Genetic polymorphisms in DNA base excision repair gene XRCC1 and the risk of squamous cell carcinoma of the head and neck

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    <p>Abstract</p> <p>Background</p> <p>The genes of base excision repair (BER) pathway have been extensively studied in the association with various human cancers. We performed a case-control study to test the association between two common single nucleotide polymorphisms (SNPs) of <it>XRCC1 </it>gene with human head and neck squamous cell carcinoma (HNSCC).</p> <p>Methods</p> <p>The genotype analysis of Arg194Trp and Arg399Gln gene polymorphisms for 92 HNSCC patients and 124 controls of cancer free subjects, in Polish population were performed using the PCR-based restriction fragment length polymorphism (PCR-RFLP) with endonuclease <it>Msp</it>I.</p> <p>Results</p> <p>No altered risk has been found individually for these SNPs, however haplotypes analysis showed high association with head and neck cancer. The highest frequency, according to wild-type of Arg194Arg and Arg399Arg genotypes, was identified for Arg194Trp-Arg399Arg haplotype (OR, 2.96; 95% CI, 1.01–8.80).</p> <p>Conclusion</p> <p>Finally, we identified the combined Arg194Trp-Arg399Arg genotype of base excision repair gene <it>XRCC1 </it>that was associated with HNSCC and may have an impact on identification of a high-risk cancer population.</p

    The latest advances in wireless communication in aviation, wind turbines and bridges

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    Present-day technologies used in SHM (Structural Health Monitoring) systems in many implementations are based on wireless sensor networks (WSN). In the context of the continuous development of these systems, the costs of the elements that form the monitoring system are decreasing. In this situation, the challenge is to select the optimal number of sensors and the network architecture, depending on the wireless system’s other parameters and requirements. It is a challenging task for WSN to provide scalability to cover a large area, fault tolerance, transmission reliability, and energy efficiency when no events are detected. In this article, fundamental issues concerning wireless communication in structural health monitoring systems (SHM) in the context of non-destructive testing sensors (NDT) were presented. Wireless technology developments in several crucial areas were also presented, and these include engineering facilities such as aviation and wind turbine systems as well as bridges and associated engineering facilities

    Human gestational N‐methyl‐d‐aspartate receptor autoantibodies impair neonatal murine brain function

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    Objective: Maternal autoantibodies are a risk factor for impaired brain development in offspring. Antibodies (ABs) against the NR1 (GluN1) subunit of the N-methyl-d-aspartate receptor (NMDAR) are among the most frequently diagnosed anti-neuronal surface ABs, yet little is known about effects on fetal development during pregnancy. Methods: We established a murine model of in utero exposure to human recombinant NR1 and isotype-matched nonreactive control ABs. Pregnant C57BL/6J mice were intraperitoneally injected on embryonic days 13 and 17 each with 240ÎŒg of human monoclonal ABs. Offspring were investigated for acute and chronic effects on NMDAR function, brain development, and behavior. Results: Transferred NR1 ABs enriched in the fetus and bound to synaptic structures in the fetal brain. Density of NMDAR was considerably reduced (up to -49.2%) and electrophysiological properties were altered, reflected by decreased amplitudes of spontaneous excitatory postsynaptic currents in young neonates (-34.4%). NR1 AB-treated animals displayed increased early postnatal mortality (+27.2%), impaired neurodevelopmental reflexes, altered blood pH, and reduced bodyweight. During adolescence and adulthood, animals showed hyperactivity (+27.8% median activity over 14 days), lower anxiety, and impaired sensorimotor gating. NR1 ABs caused long-lasting neuropathological effects also in aged mice (10 months), such as reduced volumes of cerebellum, midbrain, and brainstem. Interpretation: The data collectively support a model in which asymptomatic mothers can harbor low-level pathogenic human NR1 ABs that are diaplacentally transferred, causing neurotoxic effects on neonatal development. Thus, AB-mediated network changes may represent a potentially treatable neurodevelopmental congenital brain disorder contributing to lifelong neuropsychiatric morbidity in affected children

    A mapper-based classifier for patient subgroup prediction

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    Towards Gender Harmony-all scales translations

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    Towards Gender Harmony project - all scale translation

    Precarious Manhood Beliefs: Isomorphism and Links to Gender Beliefs Across Cultures

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    It has been 30 years since a large cross-cultural study was carried out testing people's understanding of masculinity and femininity (Williams &amp; Best, 1990). This study is part of a larger, umbrella project that is collecting data from over 40 countries to determine how people think about men and women today. In this project, we examine the isomorphism of a brief measure of precarious manhood beliefs. Precarious manhood beliefs are beliefs that manhood, relative to womanhood, is a social status that (1) is hard to earn, (2) is easy to lose, and (3) must be demonstrated repeatedly via public action. We test whether the brief, 4-item Precarious Manhood Beliefs (PMB) scale demonstrates statistical isomorphism across at least 45 (and up to 56) countries. We also examine the unique associations of the PMB with two cross-culturally validated measures of gender beliefs: the Ambivalent Sexism Inventory (Glick &amp; Fiske, 1996), and the Ambivalence toward Men Scale (Glick &amp; Fiske, 1999). Finally, we examine whether the PMB correlates with country-level indicators of gender equality (the Global Gender Gap Index) and human development (the Human Development Index)
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