Symmetry and tendency judgment of Ms ≥ 8.0 strong earthquakes in Chile

Abstract:The Ms ≥8.0 strong earthquakes occurring in Chile since 1800 were analyzed using the ternary, quaternary, and quinary commensurability methods and the butterfly structure diagram, and it was believed that the earthquake signal in Chile in 2014 is relatively strong, a large earthquake is likely to occur in Chile in 2014. An analysis of spatial epicenter migrations showed that the longitudinal and latitudinal epicenter migrations have symmetry and synchronism, and there were five obvious northward migrations and four southward migrations. The symmetry axis of the longitudinal migrations is at about 71. 7° W and that of the latitudinal migrations is at about 30° S; these spatial symmetry axes are located at the subduction zone on the western margin of South America, where two major plates (the Nazca Plate and the South American Plate) converge

Does mobile social media undermine our romantic relationships? The influence of fear of missing out (FoMO) on young people’s romantic relationship

The widespread use of social media has a transformative effect on people’s work and lives. With the increasing information explosion and more cases of social media addiction, users have been always worried that they have missed some information. FoMO (fear of missing out) of mobile users emerges. FoMO is an important theory that explicates the underlying cognitive, psychological, and social processes of dark or negative sides of online information behaviour (Shen, et al., 2021). This paper explores the impact of FoMO of post-90s generation mobile users on romantic relationship in the context of social media. The questionnaire survey was conducted in December 2017. The sample size was 274 Chinese post-90s (people born in the 1990’s) mobile social media users who were in love for at least one year and unmarried.. The statistical methods such as regression analysis were adopted. The impacts of FoMO on romantic relationship were analyzed from the perspectives of three dimensions of FoMO: cognitive, emotional and behavioural manifestations. The quantitative analysis of survey data employed the statistical package SPSS 26.0. The behavioural manifestation of FoMO has a significant negative effect on romantic relationships, while emotional and cognitive manifestations of FoMO have no significant effects on romantic relationships. This indicates that driven by FoMO, the post-90s mobile users often check the information in device frequently and subconsciously, resulting in excessive information behaviours, which does harm to the development of romantic relationship. It also implies that the view of simply treating the anxiety disorder FoMO as a psychological symptom is debatable.Conclusion. FoMO has affected users’ interpersonal relationship and behaviour in the offline environment, especially for post-90s generation users. This paper enriches the research on the effects of psychology and information behaviour of mobile social media users on their interpersonal relationship.Peer Reviewe

Mice Exposed to Chronic Intermittent Hypoxia Simulate Clinical Features of Deficiency of both Qi and Yin Syndrome in Traditional Chinese Medicine

Deficiency of both Qi and Yin Syndrome (DQYS) is one of the common syndromes in traditional Chinese medicine (TCM), mainly characterized by tiredness, emaciation, anorexia, fidget, palpitation and rapid pulse, and so forth. Currently, there is no available animal model which can reflect the clinical features of this syndrome. In the present paper, we observed the time-course changes of whole behavior, body weight, food intake, locomotive activity and electrocardiogram in mice exposed to chronic intermittent hypoxia for 6 weeks, and measured bleeding time at last according to the clinical features of DQYS and one key pathological factor. The results showed that the mice exposed to intermittent hypoxia for certain time presented lackluster hair, dull looking hair, resistance, attacking, body weight loss, food intake decline, locomotive activity decrease, heart rate quickening and T wave elevating, which were similar to the major clinical features of DQYS. Meanwhile, bleeding time shortening was also found, which was consistent with the clinical fact that DQYS often accompanied with blood stasis. The possible explanation was also outlined according to the available literature. Such findings suggested chronic intermittent hypoxia could induce similar symptoms and signs in mice accorded with the clinical features of DQYS, which provided a suitable animal model for evaluation of drugs for the treatment of this syndrome and further exploration of pathological process or correlation of the syndrome and related diseases

Graph Mining for Cybersecurity: A Survey

The explosive growth of cyber attacks nowadays, such as malware, spam, and intrusions, caused severe consequences on society. Securing cyberspace has become an utmost concern for organizations and governments. Traditional Machine Learning (ML) based methods are extensively used in detecting cyber threats, but they hardly model the correlations between real-world cyber entities. In recent years, with the proliferation of graph mining techniques, many researchers investigated these techniques for capturing correlations between cyber entities and achieving high performance. It is imperative to summarize existing graph-based cybersecurity solutions to provide a guide for future studies. Therefore, as a key contribution of this paper, we provide a comprehensive review of graph mining for cybersecurity, including an overview of cybersecurity tasks, the typical graph mining techniques, and the general process of applying them to cybersecurity, as well as various solutions for different cybersecurity tasks. For each task, we probe into relevant methods and highlight the graph types, graph approaches, and task levels in their modeling. Furthermore, we collect open datasets and toolkits for graph-based cybersecurity. Finally, we outlook the potential directions of this field for future research

Earliest ceramic drainage system and the formation of hydro-sociality in monsoonal East Asia

The earliest ceramic drainage system unearthed at the Pingliangtai site on the Central Plains of China represents an unprecedented social and environmental manipulation as societies faced surging environmental crises in the Late Holocene East Asian Monsoon region. Here we present results of excavation and a geoarchaeological survey of the water-management infrastructures and environment which reveal the operation and maintenance of a well-planned and regulated two-tiered drainage system. Rather than a ‘centralized hierarchy’, the drainage activities were mainly practised at household and communal levels, through which Pingliangtai society was drawn to more pragmatic aspects of social governance. Through their emphasis on spatial uniformity, cooperation in public affairs, and a series of technological innovations, water management at Pingliangtai gravitated to collective shared interest as the society responded to recurrent environmental contingencies. Such a pragmatic focus on public affairs constituted a previously unrecognized, alternative pathway to the development of power structure and social governance on the Central Plains regimes in late Neolithic and later times

YiQiFuMai Powder Injection Attenuates Coronary Artery Ligation-Induced Heart Failure Through Improving Mitochondrial Function via Regulating ROS Generation and CaMKII Signaling Pathways

The YiQiFuMai powder injection (YQFM), a traditional Chinese medicine (TCM) prescription re-developed based on Sheng-Mai-San, is widely applied for the treatment of cardiovascular diseases. However, its potential molecular mechanism remains obscure. The present study was designed to observe the effects of YQFM and underlying mechanisms on coronary artery ligation (CAL)-induced heart failure (HF) and cell hypoxia of 24 h oxygen-glucose deprivation (OGD) in neonatal rat ventricular myocytes (NRVMs). HF was induced by permanent CAL for 2 weeks in ICR mice. The results demonstrated that YQFM significantly attenuated CAL-induced HF via improving the cardiac function, cardiac systolic function, cardiac structure impairment, cardiac histological features and fibrosis. YQFM markedly attenuated mitochondrial dysfunction through improving mitochondrial morphology, increasing mitochondria membrane potential (Δψm), mitochondrial ROS generation and expression of Mitofusin-2 (Mfn2), meanwhile, decreasing phosphorylation of dynamin-related protein 1 (p-Drp1). Mechanistically, YQFM could significantly decrease the expression of isoforms of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase subunit NADPH oxidase 2 (NOX2), p67phox and NADPH oxidase 4 (NOX4), ultimately reducing reactive oxygen species (ROS) generation. In addition, YQFM could down-regulate expression of calcium voltage-gated channel subunit α1C (CACNA1C) and phosphorylation of calmodulin dependent protein kinase II (p-CaMKII). These results suggest that YQFM ameliorates mitochondrial function in HF mice, partially through inhibiting ROS generation and CaMKII signaling pathways. Therefore, the present study provided scientific evidence for the underlying mechanism of YQFM

Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a

BACKGROUND: Shigella bacteria cause dysentery, which remains a significant threat to public health. Shigella flexneri is the most common species in both developing and developed countries. Five Shigella genomes have been sequenced, revealing dynamic and diverse features. To investigate the intra-species diversity of S. flexneri genomes further, we have sequenced the complete genome of S. flexneri 5b strain 8401 (abbreviated Sf8401) and compared it with S. flexneri 2a (Sf301). RESULTS: The Sf8401 chromosome is 4.5-Mb in size, a little smaller than that of Sf301, mainly because the former lacks the SHI-1 pathogenicity island (PAI). Compared with Sf301, there are 6 inversions and one translocation in Sf8401, which are probably mediated by insertion sequences (IS). There are clear differences in the known PAIs between these two genomes. The bacteriophage SfV segment remaining in SHI-O of Sf8401 is clearly larger than the remnants of bacteriophage SfII in Sf301. SHI-1 is absent from Sf8401 but a specific related protein is found next to the pheV locus. SHI-2 is involved in one intra-replichore inversion near the origin of replication, which may change the expression of iut/iuc genes. Moreover, genes related to the glycine-betaine biosynthesis pathway are present only in Sf8401 among the known Shigella genomes. CONCLUSION: Our data show that the two S. flexneri genomes are very similar, which suggests a high level of structural and functional conservation between the two serotypes. The differences reflect different selection pressures during evolution. The ancestor of S. flexneri probably acquired SHI-1 and SHI-2 before SHI-O was integrated and the serotypes diverged. SHI-1 was subsequently deleted from the S. flexneri 5b genome by recombination, but stabilized in the S. flexneri 2a genome. These events may have contributed to the differences in pathogenicity and epidemicity between the two serotypes of S. flexneri