Unstable Adams operations on p-local compact groups

A p-local compact group is an algebraic object modelled on the p-local homotopy theory of classifying spaces of compact Lie groups and p-compact groups. In the study of these objects unstable Adams operations, are of fundamental importance. In this paper we define unstable Adams operations within the theory of p-local compact groups, and show that such operations exist under rather mild conditions. More precisely, we prove that for a given p-local compact group G and a sufficiently large positive integer $m$, there exists an injective group homomorphism from the group of p-adic units which are congruent to 1 modulo p^m to the group of unstable Adams operations on

Méthadone ou torture ?

Pour la première fois, la Cour européenne des droits de l’homme basée à Strasbourg se penche sur la question de savoir si les patients dépendants à l’héroïne ont un droit à poursuivre leur traitement à base de méthadone lorsqu’ils sont privés de leur liberté. S’appuyant sur l’art. 3 de la Convention, lequel interdit la torture comme les autres traitements inhumains et dégradants, la Cour estime que c’est à l’Etat, qui entend refuser l’accès à la méthadone, de prouver – sur la base d’une expertise indépendante – qu’une approche médicale autre que celle fondée sur un médicament agoniste aurait de sérieuses chances de succès dans le traitement de la dépendance du patient en cause. La présente contribution discute la portée et les limites de cet arrêt

HIL Simulation of a Mixed Islanded Power Network with External DSP Regulator

The present paper deals with the development of a modular, flexible and structured block to block approach for the study of regulators by implementing the different blocks on a DSP (digital signal processor). The proposed low-cost approach has been applied and validated by the implementation of an industrial regulator in a real time hardware-in-the-loop simulation of a mixed islanded power network including precise models of the hydraulic system. The studied network is constituted of three different types of electrical power ..

An investigation of the apparent breast cancer epidemic in France: screening and incidence trends in birth cohorts

<p>Abstract</p> <p>Background</p> <p>Official descriptive data from France showed a strong increase in breast-cancer incidence between 1980 to 2005 without a corresponding change in breast-cancer mortality. This study quantifies the part of incidence increase due to secular changes in risk factor exposure and in overdiagnosis due to organised or opportunistic screening. Overdiagnosis was defined as non progressive tumours diagnosed as cancer at histology or progressive cancer that would remain asymptomatic until time of death for another cause.</p> <p>Methods</p> <p>Comparison between age-matched cohorts from 1980 to 2005. All women residing in France and born 1911-1915, 1926-1930 and 1941-1945 are included. Sources are official data sets and published French reports on screening by mammography, age and time specific breast-cancer incidence and mortality, hormone replacement therapy, alcohol and obesity. Outcome measures include breast-cancer incidence differences adjusted for changes in risk factor distributions between pairs of age-matched cohorts who had experienced different levels of screening intensity.</p> <p>Results</p> <p>There was an 8-fold increase in the number of mammography machines operating in France between 1980 and 2000. Opportunistic and organised screening increased over time. In comparison to age-matched cohorts born 15 years earlier, recent cohorts had adjusted incidence proportion over 11 years that were 76% higher [95% confidence limits (CL) 67%, 85%] for women aged 50 to 64 years and 23% higher [95% CL 15%, 31%] for women aged 65 to 79 years. Given that mortality did not change correspondingly, this increase in adjusted 11 year incidence proportion was considered as an estimate of overdiagnosis.</p> <p>Conclusions</p> <p>Breast cancer may be overdiagnosed because screening increases diagnosis of slowly progressing non-life threatening cancer and increases misdiagnosis among women without progressive cancer. We suggest that these effects could largely explain the reported "epidemic" of breast cancer in France. Better predictive classification of tumours is needed in order to avoid unnecessary cancer diagnoses and subsequent procedures.</p