1,878 research outputs found
Dynamics of clustered opinions in complex networks
A simple model for simulating tug of war game as varying the player number in
a team is discussed to identify the slow pace of fast change. This model shows
that a large number of information sources leads slow change for the system.
Also, we introduce an opinion diffusion model including the effect of a high
degree of clustering. This model shows that the de facto standard and lock-in
effect, well-known phenomena in economics and business management, can be
explained by the network clusters.Comment: 11 pages, 2 figure
Cough hypersensitivity syndrome: A few more steps forward
© The Korean Academy of Asthma, Allergy and Clinical Immunology. Cough reflex is a vital protective mechanism against aspiration, but when dysregulated, it can become hypersensitive. In fact, chronic cough is a significant medical problem with a high degree of morbidity. Recently, a unifying paradigm of cough hypersensitivity syndrome has been proposed. It represents a clinical entity in which chronic cough is a major presenting problem, regardless of the underlying condition. Although it remains a theoretical construct, emerging evidence suggests that aberrant neurophysiology is the common etiology of this syndrome. Recent success in randomized clinical trials using a P2X3 receptor antagonist is the first major advance in the therapeutics of cough in the past 30 years; it at last provides a strategy for treating intractable cough as well as an invaluable tool for dissecting the mechanism underpinning cough hypersensitivity. Additionally, several cough measurement tools have been validated for use and will help assess the clinical relevance of cough in various underlying conditions. Along with this paradigm shift, our understanding of cough mechanisms has improved during the past decades, allowing us to continue to take more steps forward in the future
Quantitative and empirical demonstration of the Matthew effect in a study of career longevity
The Matthew effect refers to the adage written some two-thousand years ago in
the Gospel of St. Matthew: "For to all those who have, more will be given."
Even two millennia later, this idiom is used by sociologists to qualitatively
describe the dynamics of individual progress and the interplay between status
and reward. Quantitative studies of professional careers are traditionally
limited by the difficulty in measuring progress and the lack of data on
individual careers. However, in some professions, there are well-defined
metrics that quantify career longevity, success, and prowess, which together
contribute to the overall success rating for an individual employee. Here we
demonstrate testable evidence of the age-old Matthew "rich get richer" effect,
wherein the longevity and past success of an individual lead to a cumulative
advantage in further developing his/her career. We develop an exactly solvable
stochastic career progress model that quantitatively incorporates the Matthew
effect, and validate our model predictions for several competitive professions.
We test our model on the careers of 400,000 scientists using data from six
high-impact journals, and further confirm our findings by testing the model on
the careers of more than 20,000 athletes in four sports leagues. Our model
highlights the importance of early career development, showing that many
careers are stunted by the relative disadvantage associated with inexperience.Comment: 13 pages, 7 figures, 4 Tables; Revisions in response to critique and
suggestions of referee
Drug-induced cough
© 2020, Czech Academy of Sciences. Since the recognition of angiotensin-converting enzyme inhibitors (ACEIs)-induced cough, drug has been considered as a potential cause of chronic cough. This review presents recent knowledge on drug-induced coughs in patients with chronic cough. The focus is placed on ACEIs, for which there are a multitude of studies documenting their associations with cough. Additional drugs are discussed for which there are reports of cough as a side effect of treatment, and the potential mechanisms of these effects are discussed
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Evaluation of simulated O-3 production efficiency during the KORUS-AQ campaign: Implications for anthropogenic NOx emissions in Korea
We examine O3 production and its sensitivity to precursor gases and boundary layer mixing in Korea by using a 3-D global chemistry transport model and extensive observations during the KORea-US cooperative Air Quality field study in Korea, which occurred in May–June 2016. During the campaign, observed aromatic species onboard the NASA DC-8 aircraft, especially toluene, showed high mixing ratios of up to 10 ppbv, emphasizing the importance of aromatic chemistry in O3 production. To examine the role of VOCs and NOx in O3 chemistry, we first implement a detailed aromatic chemistry scheme in the model, which reduces the normalized mean bias of simulated O3 mixing ratios from –26% to –13%. Aromatic chemistry also increases the average net O3 production in Korea by 37%. Corrections of daytime PBL heights, which are overestimated in the model compared to lidar observations, increase the net O3 production rate by ~10%. In addition, increasing NOx emissions by 50% in the model shows best performance in reproducing O3 production characteristics, which implies that NOx emissions are underestimated in the current emissions inventory. Sensitivity tests show that a 30% decrease in anthropogenic NOx emissions in Korea increases the O3 production efficiency throughout the country, making rural regions ~2 times more efficient in producing O3 per NOx consumed. Simulated O3 levels overall decrease in the peninsula except for urban and other industrial areas, with the largest increase (~6 ppbv) in the Seoul Metropolitan Area (SMA). However, with simultaneous reductions in both NOx and VOCs emissions by 30%, O3 decreases in most of the country, including the SMA. This implies the importance of concurrent emission reductions for both NOx and VOCs in order to effectively reduce O3 levels in Korea
On the distribution of career longevity and the evolution of home run prowess in professional baseball
Statistical analysis is a major aspect of baseball, from player averages to
historical benchmarks and records. Much of baseball fanfare is based around
players exceeding the norm, some in a single game and others over a long
career. Career statistics serve as a metric for classifying players and
establishing their historical legacy. However, the concept of records and
benchmarks assumes that the level of competition in baseball is stationary in
time. Here we show that power-law probability density functions, a hallmark of
many complex systems that are driven by competition, govern career longevity in
baseball. We also find similar power laws in the density functions of all major
performance metrics for pitchers and batters. The use of performance-enhancing
drugs has a dark history, emerging as a problem for both amateur and
professional sports. We find statistical evidence consistent with
performance-enhancing drugs in the analysis of home runs hit by players in the
last 25 years. This is corroborated by the findings of the Mitchell Report [1],
a two-year investigation into the use of illegal steroids in major league
baseball, which recently revealed that over 5 percent of major league baseball
players tested positive for performance-enhancing drugs in an anonymous 2003
survey.Comment: 5 pages, 5 figures, 2-column revtex4 format. Revision has change of
title, a figure added, and minor changes in response to referee comment
Microscopic Theory of Rashba Interaction in Magnetic Metal
Theory of Rashba spin-orbit coupling in magnetic metals is worked out from
microscopic Hamiltonian describing d-orbitals. When structural inversion
symmetry is broken, electron hopping between -orbitals generates chiral
ordering of orbital angular momentum, which combines with atomic spin-orbit
coupling to result in the Rashba interaction. Rashba parameter characterizing
the interaction is band-specific, even reversing its sign from band to band.
Large enhancement of the Rashba parameter found in recent experiments is
attributed to the orbital mixing of 3d magnetic atoms with non-magnetic heavy
elements as we demonstrate by first-principles and tight-binding calculations.Comment: 5 pages, 2 figure
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