Issue of individual integration of children with medical disabilities in regular kindergarten

Chronic hypoxic exposure induces the alteration of blood components and skeletal muscle phenotype. Change in blood profile after exposure to 10 % hypoxic condition for 4 weeks. A. Red blood cell count. B. Hemoglobin level. C. Hematocrit value (n = 5–6 per group). D. Mass of soleus, and gastrocnemius of male under normoxia (Nx), normoxia treated with FK-506, hypoxia (Hx), and hypoxia treated with FK-506 at 8–10 weeks of age normalized to body weight (n = 5–6 mice per group). E. Appearance of skeletal muscles, including the soleus and gastrocnemius, in normoxia and hypoxia. F. The composition of muscle fiber-type was analyzed by immunostaining. Frozen sections of the soleus and gastrocnemius muscle after exposure to normoxia and hypoxia were stained with antibodies for MyHC I/slow, MyHC IIa and counterstained for laminin (n = 4–6 mice per group). *p < 0.05, **p < 0.01 compared to control. Values are means ± SEM. (PDF 5163 kb

Additional file 3: Figure S4. of Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway

The expression of genes related to ubiquitin proteasome system in skeletal muscle. The mRNA level of Murf-1 and antrogin-1 in gastrocnemius muscle (n = 4 per group). Values are means ± SEM. (PDF 58 kb