Obligate Anaerobic Lactobacillus Casei KJ686 Selectively Targets Solid Tumors and Exhibits an Antitumor Effect

Article信州医学雑誌 63(6):375-384(2015)journal articl

Advancing Globalization for Social Well-Being Studies

MEXT-Supported Program for the Strategic Research Foundation at Private Universities (2014-2018)Forming a Social Well-being Research Consortium in Asi

Circular Dichroic Power of Chiral Spiro Aromatics. Theoretical Calculation of the CD and UV Spectra of 2,2\u27 -Spirobi [2Hbenzeindene ] Derivatives

The CD and UV spectra of (2S)-2,2\u27-spirobi[2H-benz[e]indene]- 1,1\u27(3H,3\u27H)-dione (2) and (IR,I\u27S,2S)-I,I\u27,3,3\u27-tetrahydro-2,2\u27-spirobi[ 2H -benz[e]indene]-I,I\u27 -diyl diacetate (3) were theoretical1y calculated by the application of the Jt-electron SCF-CI-DV MO method. The shape of component CD and UV bands was approximated by method (A) of the Gaussian distribution, or by method (B) employing the observed band shape of the UV spectra of model compounds. The calculated CD and UV curves were in good agreement with the observed ones. For compound 2, method (A), calcd CD, Aox! = 318.5 nm (As = +5.8), 250.0 (-63.7), 213.7 (+90.8); obsd. CD, J"" = 336.2 nm (1\u2711; = +11.9), 253.2 (-96.1), 214.0 (+ 1\u2712.1). For compound 3, method (A), calcd CD, J,e,! = 279.3 nm (As = +6.5), 224.2 (-590.2), 213.7 (+753.7); obsd. CD, J\u27e" = 285.0 nm (As = +4.4), 230.2 (-961.5), 221.6 (+567.1). The absolute stereostructures of chiral spiro aromatics 2 and have been thus established by the calculation. The mechanism of the widely spread and weak CD Cotton effects of diketone 2 has been also clarified by the calculation. The calculated CD and UV spectral curves of compound 3 obtained by the application of method (B) were in excellent agreement with the observed ones: calcd CD, Ae<t = 282.5 nm (As = +10.2), 231.5 (-1139.5), 221.2 (+474.0); obsd. CD, J,,,! = 285.0 nm (As = + 4.4), 230.2 (-961.5), 221.6 (+ 567.1)

On the stability of a superspinar

The superspinar proposed by Gimon and Horava is a rapidly rotating compact entity whose exterior is described by the over-spinning Kerr geometry. The compact entity itself is expected to be governed by superstringy effects, and in astrophysical scenarios it can give rise to interesting observable phenomena. Earlier it was suggested that the superspinar may not be stable but we point out here that this does not necessarily follow from earlier studies. We show, by analytically treating the Teukolsky equations by Detwiler's method, that in fact there are infinitely many boundary conditions that make the superspinar stable, and that the modes will decay in time. It follows that we need to know more on the physical nature of the superspinar in order to decide on its stability in physical reality.Comment: 5 page

Short-Term Program on Three-Dimensional Printed Self-Help Devices for Occupational Therapy Students: A Pre-Post Intervention Study

Despite the increasing importance of digital fabrication, of which three-dimensional printing is an important aspect, educational programs in this area have not been fully developed. To utilize three-dimensional printing optimally, occupational therapists need to be familiar with this new technology, understand its scope of application, and possess certain levels of skills for producing. The purpose of this study was to examine the effectiveness of a short-term program for occupational therapy students to increase the acceptance of three-dimensional printed devices by acquiring the basic knowledge and skills of making three-dimensional printed self-help devices. The research involved an intervention study with a pre-post design. Participants comprised 112 entry-level occupational therapy students. The program consisted of two 90-minute sessions during 2019 and 2020. It included a three-part lecture series and two types of practice. The conducted pre-post questionnaires were structured into four categories: I. student profile; II. knowledge about digital fabrication technology; III. ideas and attitudes toward three-dimensional printed self-help devices; and IV. impressions and thoughts. After the program, the number of students who acquired basic knowledge of digital fabrication and who felt confident about making three-dimensional printed self-help devices significantly increased (p \u3c 0.05). The study suggested that the program was effective and assisted occupational therapy students to understand the usefulness of this new technology and be comfortable using it

チュウセイ ノ アイ トルーバドール ノ バアイ

愛とは発生的には、リビドーが特定の対象に固定することである。それはある時代、ある地域、ある階層組織社会における事象となって出る。この事象は、つねにフィクションとなり、イメージとなり、文学の特定ジャンルとしてもう一度その社会に現象する。このことによって愛をより確実なメッセージとし、追体験させる文学行為は、ホモ・サピエンスである人間固有文化活動である。トルーバドールの歌はこの次第を最もよく明らかにするものである。Love is libido\u27s fixation upon a specific object. It is a phenomenon taking place under any society in any area at any time. The relationship between fixing and fixed is a fatal, though not pre-determined, happening. The phenomenon re- presents itself once more as a form of fiction, as pieces of images, as a literary work in the society in which love is born

ジュニク ノ シュンカン ボッティチェリ カイシャク

This is a criticism to the surprise theory still current and authoritative since established half a century ago by a well-known hitorian of arts Yukio Yashiro on Botticelli\u27s "the Annunciation" in the Uffizi Museum. The paper proposes a view of Virgin Mary\u27s ecstatic moment she has just conceived the seed of God. The view is examined through the Renaissance Humanism, the painter\u27s contemporary thought milieu, to reach the conclusion that the picture is the rare case of the happy unity of Humanism and Cathoric mysticism, and a masterpiece of the then dominant arts and literary theory ut pictura_poesi

トウダイ ヘノ ブンガク タイオウ

We may well say that, compared with Marvell\u27s Ode , Milton\u27s Cromwell sonnet seems to be short of penetrating deep into our mind. When, however, we understand the ambivalent process of making the sonnet through the actual contextof his silent criticism against and obedient though unwilling loyality to Cromwell as his supreme master of the evolutionary regime, the heart aching of his grief will come up out of the inner lines of the poem. And the opressedlyricism of his mind will strike us with the signification of his high-minded way of living in the turbulent age. The Primary meaning of the poem is explicated through the contextual research of the age in which a poet lived. Thismeaning is a value that a literary study contributes to understand correlalives of men and the politico-social stratum which we have to live through