Finite-volume Hamiltonian method for coupled channel interactions in lattice QCD

Within a multi-channel formulation of $\pi\pi$ scattering, we investigate the use of the finite-volume Hamiltonian approach to resolve scattering observables from lattice QCD spectra. The asymptotic matching of the well-known L\"uscher formalism encodes a unique finite-volume spectrum. Nevertheless, in many practical situations, such as coupled-channel systems, it is advantageous to interpolate isolated lattice spectra in order to extract physical scattering parameters. Here we study the use of the Hamiltonian framework as a parameterisation that can be fit directly to lattice spectra. We find that with a modest amount of lattice data, the scattering parameters can be reproduced rather well, with only a minor degree of model dependence.Comment: 25 pages, 16 figure

Extreme non-linear response of ultra-narrow optical transitions in cavity QED for laser stabilization

We explore the potential of direct spectroscopy of ultra-narrow optical transitions of atoms localized in an optical cavity. In contrast to stabilization against a reference cavity, which is the approach currently used for the most highly stabilized lasers, stabilization against an atomic transition does not suffer from Brownian thermal noise. Spectroscopy of ultra-narrow optical transitions in a cavity operates in a very highly saturated regime in which non-linear effects such as bistability play an important role. From the universal behavior of the Jaynes-Cummings model with dissipation, we derive the fundamental limits for laser stabilization using direct spectroscopy of ultra-narrow atomic lines. We find that with current lattice clock experiments, laser linewidths of about 1 mHz can be achieved in principle, and the ultimate limitations of this technique are at the 1 $\mu$ Hz level.Comment: 5 pages, 4 figure

Dynamical Creation of Fractionalized Vortices and Vortex Lattices

We investigate dynamic creation of fractionalized half-quantum vortices in Bose-Einstein condensates of sodium atoms. Our simulations show that both individual half-quantum vortices and vortex lattices can be created in rotating optical traps when additional pulsed magnetic trapping potentials are applied. We also find that a distinct periodically modulated spin-density-wave spatial structure is always embedded in square half-quantum vortex lattices; this structure can be conveniently probed by taking absorption images of ballistically expanding cold atoms in a Stern-Gerlach field.Comment: 4 pages, 3 figures; published versio

Multiparty Quantum Secret Sharing Based on Entanglement Swapping

A multiparty quantum secret sharing (QSS) protocol is proposed by using swapping quantum entanglement of Bell states. The secret messages are imposed on Bell states by local unitary operations. The secret messages are split into several parts and each part is distributed to a party so that no action of a subset of all the parties but their entire cooperation is able to read out the secret messages. In addition, the dense coding is used in this protocol to achieve a high efficiency. The security of the present multiparty QSS against eavesdropping has been analyzed and confirmed even in a noisy quantum channel.Comment: 5 page

Warped flavor symmetry predictions for neutrino physics

A realistic five-dimensional warped scenario with all standard model fields propagating in the bulk is proposed. Mass hierarchies would in principle be accounted for by judicious choices of the bulk mass parameters, while fermion mixing angles are restricted by a $\Delta(27)$ flavor symmetry broken on the branes by flavon fields. The latter gives stringent predictions for the neutrino mixing parameters, and the Dirac CP violation phase, all described in terms of only two independent parameters at leading order. The scheme also gives an adequate CKM fit and should be testable within upcoming oscillation experiments.Comment: 19 pages, 2 figue

Quantitation of intracellular NAD(P)H can monitor an imbalance of DNA single strand break repair in base excision repair deficient cells in real time

DNA single strand breaks (SSBs) are one of the most frequent DNA lesions in genomic DNA generated either by oxidative stress or during the base excision repair pathways. Here we established a new real-time assay to assess an imbalance of DNA SSB repair by indirectly measuring PARP-1 activation through the depletion of intracellular NAD(P)H. A water-soluble tetrazolium salt is used to monitor the amount of NAD(P)H in living cells through its reduction to a yellow colored water-soluble formazan dye. While this assay is not a direct method, it does not require DNA extraction or alkaline treatment, both of which could potentially cause an artifactual induction of SSBs. In addition, it takes only 4 h and requires less than a half million cells to perform this measurement. Using this assay, we demonstrated that the dose- and time-dependent depletion of NAD(P)H in XRCC1-deficient CHO cells exposed to methyl methanesulfonate. This decrease was almost completely blocked by a PARP inhibitor. Furthermore, methyl methanesulfonate reduced NAD(P)H in PARP-1+/+cells, whereas PARP-1¿/¿ cells were more resistant to the decrease in NAD(P)H. These results indicate that the analysis of intracellular NAD(P)H level using water-soluble tetrazolium salt can assess an imbalance of SSB repair in living cells in real time

Magnetic structure of free cobalt clusters studied with Stern-Gerlach deflection experiments

We have studied the magnetic properties of free cobalt clusters in two semi-independent Stern-Gerlach deflection experiments at temperatures between 60 and 307 K. We find that clusters consisting of 13 to 200 cobalt atoms exhibit behavior that is entirely consistent with superparamagnetism, though complicated by finite-system fluctuations in cluster temperature. By fitting the data to the Langevin function, we report magnetic moments per atom for each cobalt cluster size and compare the results of our two measurements and all those performed previously. In addition to a gradual decrease in moment per atom with increasing size, there are oscillations that appear to be caused by geometrical shell structure. We discuss our observations in light of the two competing models for Langevin-like magnetization behavior in free clusters, superparamagnetism and adiabatic magnetization, and conclude that the evidence strongly supports the superparamagnetic model

Generic Constraints on the Relativistic Mean-Field and Skyrme-Hartree-Fock Models from the Pure Neutron Matter Equation of State

We study the nuclear symmetry energy S(rho) and related quantities of nuclear physics and nuclear astrophysics predicted generically by relativistic mean-field (RMF) and Skyrme-Hartree-Fock (SHF) models. We establish a simple prescription for preparing equivalent RMF and SHF parametrizations starting from a minimal set of empirical constraints on symmetric nuclear matter, nuclear binding energy and charge radii, enforcing equivalence of their Lorenz effective masses, and then using the pure neutron matter (PNM) equation of state (EoS) obtained from ab-initio calculations to optimize the pure isovector parameters in the RMF and SHF models. We find the resulting RMF and SHF parametrizations give broadly consistent predictions of the symmetry energy J and its slope parameter L at saturation density within a tight range of <~2 MeV and <~6 MeV respectively, but that clear model dependence shows up in the predictions of higher-order symmetry energy parameters, leading to important differences in (a) the slope of the correlation between J and L from the confidence ellipse, (b) the isospin-dependent part of the incompressibility of nuclear matter K_tau, (c) the symmetry energy at supra-saturation densities, and (d) the predicted neutron star radii. The model dependence can lead to about 1-2 km difference in predictions of the neutron star radius given identical predicted values of J, L and symmetric nuclear matter (SNM) saturation properties. Allowing the full freedom in the effective masses in both models leads to constraints of 30<~J<~31.5 MeV, 35<~L<~60 MeV, -330<~K_tau<~-216 MeV for the RMF model as a whole and 30<~J<~33 MeV, 28<~L<~65 MeV, -420<~K_tau<~-325 MeV for the SHF model as a whole. Notably, given PNM constraints, these results place RMF and SHF models as a whole at odds with some constraints on K_tau inferred from giant monopole resonance and neutron skin experimental results.Comment: 15 pages, 7 figures, 4 table

ELAV links paused Pol II to alternative polyadenylation in the Drosophila nervious system

Alternative polyadenylation (APA) has been implicated in a variety of developmental and disease processes. A particularly dramatic form of APA occurs in the developing nervous system of flies and mammals, whereby various developmental genes undergo coordinate 3' UTR extension. In Drosophila, the RNA-binding protein ELAV inhibits RNA processing at proximal polyadenylation sites, thereby fostering the formation of exceptionally long 3' UTRs. Here, we present evidence that paused Pol II promotes recruitment of ELAV to extended genes. Replacing promoters of extended genes with heterologous promoters blocks normal 3' extension in the nervous system, while extension-associated promoters can induce 3' extension in ectopic tissues expressing ELAV. Computational analyses suggest that promoter regions of extended genes tend to contain paused Pol II and associated cis-regulatory elements such as GAGA. ChIP-seq assays identify ELAV in the promoter regions of extended genes. Our study provides evidence for a regulatory link between promoter-proximal pausing and APA