12,688 research outputs found

    Changemaker values within the Foundation Degree Learning and Teaching and the development of a Teaching Assistant Teachmeet Event

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    An article exploring the Changemaker values within the planning and delivery of the TeachMeet for teaching Assistants event

    Towards a third phase of regulation: re-imagining private security in South Africa

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    With the legislative review of police oversight currently taking place in South Africa, now is a good time to reflect on the regulation of the private security industry. This article does so by focusing on three challenges to the current private security regulatory systems: the increased pluralisation of policing within public spaces; the operation of hidden sectors within the industry; and the nature of criminal abuses perpetuated by the industry. We do this to demonstrate the need for a re-imagining of what regulation, especially state regulation, of this industry should entail. The aim of the article is not to review the current legislation or to identify gaps and propose means of filling those gaps, but rather to reflect on the underlying premises informing the legislation and propose a shift in thinking. We do this by briefly identifying two phases of state regulation in South Africa, implemented before and after the change to a new democratic dispensation, and suggest that we are now entering a third phase of regulation. We conclude with suggestions as to what this third phase may entail

    Enterprise modelling : building a product lifecycle (PLM) model as a component of the integrated vision of the enterprise

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    Enterprise modelling has proved to be an efficient tool to study organisations structure and facilitate decision making. The enterprise is a complex system that is required to use its processes to generate value in a given environment (concurrent, market, suppliers and humanity). We focus on three management disciplines: Product Lifecycle Management (PLM), Supply Chain Management (SCM) and Customer Relationship Management (CRM). These business processes are so intertwined that the enterprise has to concentrate on the three to attain its economic objectives. To enhance the development of PLM, SCM and CRM models, the enterprise needs to capitalise the knowledge necessary to adapt and apply modelling techniques. Knowledge Management (KM) is a key factor to give a unified enterprise vision. Firstly, we propose an integrated enterprise model depicting the interactions between PLM, SCM, CRM and KM models. But a state of the art showed that PLM models are scarce. Most of the PLM models found depends strongly on the particular case studied and can not be used with other enterprises. After defining the most important components of the PLM vision, we propose to organise these components into a formalised way. The study of SCM and CRM models proved to be helpful to structure these components. Finally the validation methodology that is to be established in our coming research works is not only to be used with the PLM model presented in this paper but with SCM and CRM models also.Product Lifecycle Management (PLM), Enterprise modelling, Enterprise systems

    Comparison of three radio-frequency discharge modes on the treatment of breast cancer cells in vitro

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    Non-thermal plasmas (NTPs) are known for their ability to induce thermal-free cytotoxic effects on cancer cells. However, as the variety of NTP devices increases, comparison of their cytotoxic effect becomes increasingly essential. In this work, we compare the cytotoxicity of three different radio-frequency NTPs. MDA-MB-231 triple negative breast cancer cells are treated in suspension in DMEM culture medium by the effluents of a single radiofrequency (RF) discharge device operating in three modes, namely the and modes of the capacitively coupled radio-frequency (CCRF) discharge and a RF plasma jet mode. All three discharge modes reduce the proliferative capacity of MDA-MB-231 cells, but the treatment time required to reach the same efficacy is more than ten times longer using the and the modes than using the jet mode. In all cases, using the appropriate treatment time, cells exhibit an impaired proliferation and eventually start to show signs of cell death (about 48 h after treatment). The three discharge modes also induce nuclear DNA damages. Plasma-produced H2O2 was not found to contribute to the cytotoxicity of the treatment. Furthermore, short-lived reactive species (gas phase or liquid phase species with a lifetime below 1 s) are expected to play a dominant role over the long-lived reactive species in the anti-cancer effect of all three discharge modes
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