Anesthetic Management of a Brown Bear (Ursus arctos) Captive Undergoing Incisional Biopsy of a Skin Nodule

Background: The brown bear (Ursus arctos) is considered one of the largest terrestrial carnivores, native from temperate forest regions of North America, Europe and Asia. In Brazil, they are founded in captivity and their safe capture and immobilization are obtained with one effective anesthesia for management and surgical and diagnostic procedures. Some anesthetic protocols are described for these purposes, however, there is a lack for data on the anesthetic and adverse effects they have on bears when used. The aim of this case is to report the use and effects of the association of dexmedetomidine with tiletamine and zolazepam in the chemical containment of a captive adult brown bear.Case: A 33-year-old female brown bear, weighing 100 kg, belonging to the Zoobotanic Park of Teresina, Piauí, Brazil, was chemically immobilized for an incisional biopsy of a cutaneous nodule with 1.0 cm diameter in the right face region. The anesthetic protocol included 6 μg/kg of dexmedetomidine associated with 3 mg/kg of tiletamine and zolazepam, administered intramuscularly by dart into the gluteal region of the right pelvic limb. The animal showed moderate ataxia at 5 min and assumed sternal decubitus 7 min after anesthetic administration. The bear's degree of sedation was considered adequate and safe to perform the biopsy at 10 min after administration. Heart rate (47 ± 3 bpm), respiratory rate (17 ± 2 mpm) and rectal temperature (38.7 ± 0.1ºC) were monitored. The bear remained immobile and unconscious throughout the procedure, with intense muscle relaxation, bilateral eyeball rotation, absent lateral palpebral reflex and mild medial reflex and without nystagmus. Complementary sedative doses were not necessary. At the beginning of anesthetic recovery, the bear received 6 µg/kg of atipamezole, intramuscularly. After 25 min of administration of atipamezole, the animal showed signs of recovery in the level of consciousness and reactivity to external stimuli, and assumed the quadrupedal position at 60 min after reverser application.Discussion: Even in captivity, the bears behavior is unpredictable and attack can occur, causing trauma or death to people. For this, the chemical immobilization is important to keep safety of everyone. This procedure was performed using blowgun-assisted darts thrown by a staff member who had experience in using this method, who darted accurately and effectively. The latency time observed after administration of the anesthetic protocol used is similar to reported in other studies with bears that also received intramuscular dexmedetomidine and tiletamine and zolazepam and showed intense muscle relaxation and immobility. The doses used contributed to the absence of bradycardia and hypoventilation and, performing the procedure in the morning, when the temperature is milder in the city, minimized the chance of hyperthermia and thermal stress in the animal, not requiring body cooling. The use of dexmedetomidine in chemical containment protocols for short and minimally invasive procedures allows the subsequent use of its antagonist, atipamezole, contributing to a shorter recovery time, return of the animal’s degree of consciousness and lower incidence of ataxia after assuming a quadrupedal position. The anesthetic protocol used was considered efficient, providing a quick and gentle chemical containment, adequate anesthetic plan and good anesthetic recovery in an adult brown bear from captivity.Keywords:atipamezole, dexmedetomidine, wildlife.Título: Manejo anestésico de um urso pardo (Ursus arctos) cativo submetido a biópsia incisional de nódulo cutâneoDescritores: atipamezole, dexmedetomidine, animais selvagens

Bloqueio peribulbar com ropivacaína a 1% guiado por ultrassonografia em cães: avaliação e padronização da técnica

he regional blocks are used in veterinary medicine as part of a balanced anesthesia protocol, next to inhalational anesthesia. The effectiveness, however, is variable front due to the difficulty of achieving anatomical references vague or inexperience of the performer. The peribulbar has indicated for ophthalmic procedures in general, but the technique requires care by the proximity of the needle to the eyeball that if an error occurs, can lead to perforation of the same. The monitoring with ultrasound image may be a great tool in the implementation of local techniques, especially the delicate and access-threatening injuries as peribulbar block. Aiming to standardize the technique of peribulbar guided by ultrasound in dogs, this work was performed with the following: in the first phase, four dogs euthanized recently underwent peribulbar injection guided by ultrasound with the administration of methylene blue 1% for identification of the structures affected by ocular and orbital solution. The second phase occurred in the form of comparative study of the duration of sensory block, motor and ophthalmic complications observed during the assessment of the conventional peribulbar and ultrasound-guided technique with 1% ropivacaine in 15 healthy dogs. The results showed akinesia, motor and sensory block equivalents, with the occurrence and severity of ophthalmic complications similar, except the conjunctival haemorrhage had major repercussions in the way traditional bulbs blocked. It was concluded that the standardization of the peribulbar technique with lower single puncture guided by ultrasound has applicability in dogs, with the advantage of promoting visual confirmation of the accuracy of the technique and the correct deposition of the anesthetic agent in the proper place, concomitantly the preservation of eye structures, with satisfactory quality and duratio

Anestesia peribulbar guiada por ultrassom com diferentes volumes de ropivacaína a 1 por cento associada ou não ao bicarbonato de sódio em cães

Seven dogs were subjected to inhalation anesthesia with isoflurane to allow the realization of peribulbar block, with lower single puncture, guided by ultrasound with 1% ropivacaine, and thus prove the effectiveness of this blocking technique guided in reducing anesthetic volume of ropivacaine 1%, and evaluate possible potentiating effects such as reducing the latency and anesthetic volume used and ophthalmic complications associated with the anesthetic alkalinization with sodium bicarbonate 0,33%. We evaluated two different volumes of 1% ropivacaine (0.2 ml / kg and 0.1 ml / kg) with or without sodium bicarbonate to 0.33% which when added to anesthetic raised the pH of the solution anesthetic to 6.0. Once performed peribulbar block, with lower single puncture guided by ultrasound time required to place the centralization of the eye bulb was timed, and the animals remained anesthetized for the measurement of intraocular pressure was carried out immediately and 15 minutes after blockade and completed this measurement, anesthesia was terminated. With dogs the following parameters already awake were evaluated intraocular pressure, pupil size, the duration and intensity of motor block, sensory (performed by esthesiometry corneal with esthesiometer Cochet and Bonnet), and observation of ophthalmic complications as chemosis, conjunctival hyperemia, subconjunctival hematoma, pruritus, and ocular secretion resulting from the anesthetic technique or employee drug. Statistical analyzes were conducted with the free software Rstudio. nonparametric variables, ordinal variables and categorical variables were evaluated using the statistical test ANOVA type or ATS. Parametric continuous variables were assessed by linear mixed model for repeated measures. The Test Kendall Tau-b was used to verify possible correlations between variables. Aside from fotomotor reflex (G0,1: 30 (0-90) and G0,2: 150 (0-210 minutes), there was no significant difference between groups when compared to latency, intraocular pressure, pupil size, the durations and quality of sensory and motor block, and ophthalmic complications, but there was significant difference when comparing times within the same group for all variables. Thus it was concluded that among the evaluated volumes of 1% ropivacaine in the lock US peribulbar guided in dogs, there was a better clinical performance related to the intensity and duration of sensory and motor block, with a volume of 0.2 ml / kg. the addition of 0.33% NaHCO3 no added benefits, such as potentiation of action or reduction of latency anesthetic, but no significant ophthalmic complications directly related to its administration or the 1% ropivacaine.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP

Reconhecimento e avaliação da dor em bovinos: Revisão

A dor, além de ser uma experiência desagradável, é um mecanismo importante de proteção do organismo e manutenção da vida, e o entendimento da sua fisiologia, suas principais causas, seu reconhecimento e avaliação em bovinos é necessário para o direcionamento do tratamento ideal, que promova o bem-estar animal minimizando os prejuízos na cadeia produtiva. A avaliação da dor em bovinos representa um desafio e o seu tratamento é considerado muitas vezes inadequado, devido à falta de conhecimento sobre os comportamentos relacionados a dor e a crença que pela sua rusticidade e resistência sintam menos dor que os pequenos animais, ou até mesmo não setem dor. Os estudos a respeito da avaliação da com base no comportamento tem recebido atenção crescente, e geralmente comportamentos de dor em bovinos descritos na literatura são aqueles frequentemente associados a doenças como mastites, metrites, pododermatites, artrite séptica, peritonite, miíases externas, ou práticas de manejo como castrações, marcação com ferro quente e descornas. Algumas ferramentas, como escalas de avaliação da dor, estão sendo produzidas e utilizadas para a avaliação da dor em bovinos, e é notória a percepção da sociedade sobre a importância do reconhecimento e tratamento da dor não só em bovinos, mas em todos os animais de produção, objetivando sobretudo o bem-estar animal

Uso da Dexmedetomidina para a contenção química de uma Anta Brasileira (Tapirus terrestris) de cativeiro

Background:  The Brazilian tapir (Tapirus terrestris), considered the largest land mammal in South America, is a vulnerable species in terms of its degree of conservation. In captivity, its health is evaluated through behavioral and physical observation and laboratory exams, and in some cases, chemical restraint, to reduce stress. Dissociative anesthetics and sedatives are used for the sedation of these animals, and few studies have reported the use of dexmedetomidine and its effects when associated with other drugs in chemical containment protocols; therefore, this work reports its use, in conjunction with ketamine and midazolam, in a young Brazilian tapir. Case:  A male Brazilian tapir, male, weighing 89 kg, 1 and a half year old,  housed at CETAS in Rio Branco, Acre, was chemically restrained with dexmedetomidine (7 µg/kg), ketamine (1.5 mg/kg), and midazolam (0.2 mg/kg) for venous blood collection, oral and rectal mucosal swabs, and microchipping. The protocol was administered intramuscularly to the right triceps brachii, after physical restraint. After 5 min of application, the animal assumed sternal recumbency and presented reflux. After 15 min, the patient was placed in the right lateral decubitus position. During collection, heart rate (48 ± 10 bpm), respiratory frequency (29 ± 1 mpm), rectal temperature (38.1 ± 0.18 °C), oxyhemoglobin saturation (97 ± 1%), and electrocardiographic tracing were recorded. The tapir showed deep sedation, immobility, good muscle relaxation, discreet medial palpebral reflex, and bilateral rotation of the eyeball. After 40 min of protocol administration, sedative reversal was performed intramuscularly with 14 µg/kg atipamezole. Five min after administration, the tapir showed signs of mild sedation. After 10 min, he assumed the quadrupedal position, remained in this position for 8 min, and gently resumed the sternal decubitus. After only 20 min, he resumed the quadrupedal position, with mild ataxia and good muscular and conscious tone. After 50 min, the patient was discharged from anesthesia. Discussion: Domestic horses are phylogenetically close to tapirs, so the choice of drugs and doses of the protocol used was based on their use in horses, and on studies carried out with tapirs as well. Despite being docile and passive, the tapir was not conditioned and did not allow the manipulation and collection of samples collaboratively; therefore, it was chemically contained. The physical restraint performed did not generate satisfactory immobilization of the tapir, resulting in agitation and stress and causing the needle to break. The reflux presented by the tapir minutes after sedation and at recovery was induced by dexmedetomidine, and only the undigested banana pieces were offered to the animal. Reflux plus stress from extensive fasting and suboptimal physical restraint was responsible for the change in the tapir's eating behavior, with possible stress gastritis 24 h after chemical restraint. Only one study reported the use of dexmedetomidine in tapirs, associated with continuous infusions of ketamine, midazolam and guaiacol glyceryl ether for moderate to long-term field procedures. Sedative reversal of dexmedetomidine by atipamezole reduced the recovery time and the risk of death from cardiorespiratory depression. The anesthetic combination used was effective, promoting immobility, muscle relaxation, and stability of the physical parameters evaluated, with rapid and gentle induction and an adequate level of sedation for the objective, good sedative reversal, and anesthetic recovery. Keywords: anesthesia, anesthetic management, wild animals, mammals, sedative.Antecedentes: Considerado o maior mamífero terrestre da América do Sul, a Anta brasileira (Tapirus terrestris), é uma espécie vulnerável quanto ao seu grau de conservação. Em cativeiro, sua saúde é avaliada por meio da observação comportamental, física e por exames, sendo necessária, e alguns casos, a contenção química, reduzindo o estresse. Anestésicos dissociativos e sedativos são utilizados para a sedação destes animais, e poucos estudos relatam o uso da dexmedetomidina e seus efeitos quando associadas a outros fármacos em protocolos de contenção química, por isso, este trabalho relata o seu emprego, com cetamina e midazolam, em uma anta brasileira jovem. Caso:  Uma anta brasileira, macho, 89 kg, um ano e meio de idade, lotada no CETAS de Rio Branco, Acre, foi contida quimicamente com dexmedetomidina (7µg/kg), cetamina (1,5mg/kg) e midazolam (0,2 mg/kg), para a coleta de sangue venoso, swab da mucosa oral e retal, e microchipagem. O protocolo foi administrado por via intramuscular, no tríceps braquial direito, após contenção física. Após cinco minutos da aplicação, o animal assumiu decúbito esternal, e apresentou refluxo. Passados 15 minutos, este foi posicionado em decúbito lateral direito. Durante a coleta, foram monitoradas, a frequência cardíaca (48 ± 10 bpm), frequência respiratória (29 ± 1 mpm), temperatura retal (38,1 ± 0,18 °C), saturação da oxihemoglobina (97 ± 1%) e o traçado eletrocardiográfico pelo monitor multiparamétrico. A anta apresentou grau de sedação profundo, imobilidade, bom relaxamento muscular, reflexo palpebral medial discreto e rotação bilateral do globo ocular. Após 40 minutos da administração do protocolo, foi realizada a reversão sedativa com 14 µg/kg atipamezole, por via intramuscular. Depois de cinco minutos dessa administração, a anta apresentou sinais de grau de sedação leve. Após dez minutos, assumiu a posição quadrupedal, permaneceu nesta por oito minutos, e retomou o decúbito esternal, de modo suave. Somente após 20 minutos, reassumiu a posição quadrupedal, com leve ataxia, bom tônus muscular e consciente. Depois de 50 minutos, recebeu alta anestésica. Discussão: Os cavalos domésticos são filogeneticamente próximos das antas, por isso a escolha das drogas e das doses do protocolo utilizado foi baseada em seu uso em cavalos, e também em estudos realizados com antas. Apesar de dócil e passiva, a anta não era condicionada e não permitia a manipulação e coleta de amostras de forma colaborativa; portanto, estava quimicamente contido. A contenção física realizada não gerou uma imobilização satisfatória da anta, resultando em agitação e estresse e causando a quebra da agulha. O refluxo apresentado pela anta minutos após a sedação e na recuperação foi induzido pela dexmedetomidina, e apenas os pedaços de banana não digeridos foram oferecidos ao animal. Refluxo mais estresse de jejum prolongado e contenção física abaixo do ideal foi responsável pela mudança no comportamento alimentar da anta, com possível gastrite de estresse 24 h após a contenção química. Apenas um estudo relatou o uso de dexmedetomidina em antas, associado a infusões contínuas de cetamina, midazolam e guaiacol gliceril éter para procedimentos de campo de moderada a longa duração. A reversão sedativa da dexmedetomidina pelo atipamezol reduziu o tempo de recuperação e o risco de morte por depressão cardiorrespiratória. A combinação anestésica utilizada foi eficaz, promovendo imobilidade, relaxamento muscular e estabilidade dos parâmetros físicos avaliados, com indução rápida e suave e nível adequado de sedação para o objetivo, boa reversão sedativa e recuperação anestésica

Uso da Dexmedetomidina para a contenção química de uma Anta Brasileira (Tapirus terrestris) de cativeiro

Background:  The Brazilian tapir (Tapirus terrestris), considered the largest land mammal in South America, is a vulnerable species in terms of its degree of conservation. In captivity, its health is evaluated through behavioral and physical observation and laboratory exams, and in some cases, chemical restraint, to reduce stress. Dissociative anesthetics and sedatives are used for the sedation of these animals, and few studies have reported the use of dexmedetomidine and its effects when associated with other drugs in chemical containment protocols; therefore, this work reports its use, in conjunction with ketamine and midazolam, in a young Brazilian tapir. Case:  A male Brazilian tapir, male, weighing 89 kg, 1 and a half year old,  housed at CETAS in Rio Branco, Acre, was chemically restrained with dexmedetomidine (7 µg/kg), ketamine (1.5 mg/kg), and midazolam (0.2 mg/kg) for venous blood collection, oral and rectal mucosal swabs, and microchipping. The protocol was administered intramuscularly to the right triceps brachii, after physical restraint. After 5 min of application, the animal assumed sternal recumbency and presented reflux. After 15 min, the patient was placed in the right lateral decubitus position. During collection, heart rate (48 ± 10 bpm), respiratory frequency (29 ± 1 mpm), rectal temperature (38.1 ± 0.18 °C), oxyhemoglobin saturation (97 ± 1%), and electrocardiographic tracing were recorded. The tapir showed deep sedation, immobility, good muscle relaxation, discreet medial palpebral reflex, and bilateral rotation of the eyeball. After 40 min of protocol administration, sedative reversal was performed intramuscularly with 14 µg/kg atipamezole. Five min after administration, the tapir showed signs of mild sedation. After 10 min, he assumed the quadrupedal position, remained in this position for 8 min, and gently resumed the sternal decubitus. After only 20 min, he resumed the quadrupedal position, with mild ataxia and good muscular and conscious tone. After 50 min, the patient was discharged from anesthesia. Discussion: Domestic horses are phylogenetically close to tapirs, so the choice of drugs and doses of the protocol used was based on their use in horses, and on studies carried out with tapirs as well. Despite being docile and passive, the tapir was not conditioned and did not allow the manipulation and collection of samples collaboratively; therefore, it was chemically contained. The physical restraint performed did not generate satisfactory immobilization of the tapir, resulting in agitation and stress and causing the needle to break. The reflux presented by the tapir minutes after sedation and at recovery was induced by dexmedetomidine, and only the undigested banana pieces were offered to the animal. Reflux plus stress from extensive fasting and suboptimal physical restraint was responsible for the change in the tapir's eating behavior, with possible stress gastritis 24 h after chemical restraint. Only one study reported the use of dexmedetomidine in tapirs, associated with continuous infusions of ketamine, midazolam and guaiacol glyceryl ether for moderate to long-term field procedures. Sedative reversal of dexmedetomidine by atipamezole reduced the recovery time and the risk of death from cardiorespiratory depression. The anesthetic combination used was effective, promoting immobility, muscle relaxation, and stability of the physical parameters evaluated, with rapid and gentle induction and an adequate level of sedation for the objective, good sedative reversal, and anesthetic recovery. Keywords: anesthesia, anesthetic management, wild animals, mammals, sedative.Antecedentes: Considerado o maior mamífero terrestre da América do Sul, a Anta brasileira (Tapirus terrestris), é uma espécie vulnerável quanto ao seu grau de conservação. Em cativeiro, sua saúde é avaliada por meio da observação comportamental, física e por exames, sendo necessária, e alguns casos, a contenção química, reduzindo o estresse. Anestésicos dissociativos e sedativos são utilizados para a sedação destes animais, e poucos estudos relatam o uso da dexmedetomidina e seus efeitos quando associadas a outros fármacos em protocolos de contenção química, por isso, este trabalho relata o seu emprego, com cetamina e midazolam, em uma anta brasileira jovem. Caso:  Uma anta brasileira, macho, 89 kg, um ano e meio de idade, lotada no CETAS de Rio Branco, Acre, foi contida quimicamente com dexmedetomidina (7µg/kg), cetamina (1,5mg/kg) e midazolam (0,2 mg/kg), para a coleta de sangue venoso, swab da mucosa oral e retal, e microchipagem. O protocolo foi administrado por via intramuscular, no tríceps braquial direito, após contenção física. Após cinco minutos da aplicação, o animal assumiu decúbito esternal, e apresentou refluxo. Passados 15 minutos, este foi posicionado em decúbito lateral direito. Durante a coleta, foram monitoradas, a frequência cardíaca (48 ± 10 bpm), frequência respiratória (29 ± 1 mpm), temperatura retal (38,1 ± 0,18 °C), saturação da oxihemoglobina (97 ± 1%) e o traçado eletrocardiográfico pelo monitor multiparamétrico. A anta apresentou grau de sedação profundo, imobilidade, bom relaxamento muscular, reflexo palpebral medial discreto e rotação bilateral do globo ocular. Após 40 minutos da administração do protocolo, foi realizada a reversão sedativa com 14 µg/kg atipamezole, por via intramuscular. Depois de cinco minutos dessa administração, a anta apresentou sinais de grau de sedação leve. Após dez minutos, assumiu a posição quadrupedal, permaneceu nesta por oito minutos, e retomou o decúbito esternal, de modo suave. Somente após 20 minutos, reassumiu a posição quadrupedal, com leve ataxia, bom tônus muscular e consciente. Depois de 50 minutos, recebeu alta anestésica. Discussão: Os cavalos domésticos são filogeneticamente próximos das antas, por isso a escolha das drogas e das doses do protocolo utilizado foi baseada em seu uso em cavalos, e também em estudos realizados com antas. Apesar de dócil e passiva, a anta não era condicionada e não permitia a manipulação e coleta de amostras de forma colaborativa; portanto, estava quimicamente contido. A contenção física realizada não gerou uma imobilização satisfatória da anta, resultando em agitação e estresse e causando a quebra da agulha. O refluxo apresentado pela anta minutos após a sedação e na recuperação foi induzido pela dexmedetomidina, e apenas os pedaços de banana não digeridos foram oferecidos ao animal. Refluxo mais estresse de jejum prolongado e contenção física abaixo do ideal foi responsável pela mudança no comportamento alimentar da anta, com possível gastrite de estresse 24 h após a contenção química. Apenas um estudo relatou o uso de dexmedetomidina em antas, associado a infusões contínuas de cetamina, midazolam e guaiacol gliceril éter para procedimentos de campo de moderada a longa duração. A reversão sedativa da dexmedetomidina pelo atipamezol reduziu o tempo de recuperação e o risco de morte por depressão cardiorrespiratória. A combinação anestésica utilizada foi eficaz, promovendo imobilidade, relaxamento muscular e estabilidade dos parâmetros físicos avaliados, com indução rápida e suave e nível adequado de sedação para o objetivo, boa reversão sedativa e recuperação anestésica

Anesthetic Management of a Brown Bear (Ursus arctos) Captive Undergoing Incisional Biopsy of a Skin Nodule

Background: The brown bear (Ursus arctos) is considered one of the largest terrestrial carnivores, native from temperate forest regions of North America, Europe and Asia. In Brazil, they are founded in captivity and their safe capture and immobilization are obtained with one effective anesthesia for management and surgical and diagnostic procedures. Some anesthetic protocols are described for these purposes, however, there is a lack for data on the anesthetic and adverse effects they have on bears when used. The aim of this case is to report the use and effects of the association of dexmedetomidine with tiletamine and zolazepam in the chemical containment of a captive adult brown bear.Case: A 33-year-old female brown bear, weighing 100 kg, belonging to the Zoobotanic Park of Teresina, Piauí, Brazil, was chemically immobilized for an incisional biopsy of a cutaneous nodule with 1.0 cm diameter in the right face region. The anesthetic protocol included 6 μg/kg of dexmedetomidine associated with 3 mg/kg of tiletamine and zolazepam, administered intramuscularly by dart into the gluteal region of the right pelvic limb. The animal showed moderate ataxia at 5 min and assumed sternal decubitus 7 min after anesthetic administration. The bear's degree of sedation was considered adequate and safe to perform the biopsy at 10 min after administration. Heart rate (47 ± 3 bpm), respiratory rate (17 ± 2 mpm) and rectal temperature (38.7 ± 0.1ºC) were monitored. The bear remained immobile and unconscious throughout the procedure, with intense muscle relaxation, bilateral eyeball rotation, absent lateral palpebral reflex and mild medial reflex and without nystagmus. Complementary sedative doses were not necessary. At the beginning of anesthetic recovery, the bear received 6 µg/kg of atipamezole, intramuscularly. After 25 min of administration of atipamezole, the animal showed signs of recovery in the level of consciousness and reactivity to external stimuli, and assumed the quadrupedal position at 60 min after reverser application.Discussion: Even in captivity, the bears behavior is unpredictable and attack can occur, causing trauma or death to people. For this, the chemical immobilization is important to keep safety of everyone. This procedure was performed using blowgun-assisted darts thrown by a staff member who had experience in using this method, who darted accurately and effectively. The latency time observed after administration of the anesthetic protocol used is similar to reported in other studies with bears that also received intramuscular dexmedetomidine and tiletamine and zolazepam and showed intense muscle relaxation and immobility. The doses used contributed to the absence of bradycardia and hypoventilation and, performing the procedure in the morning, when the temperature is milder in the city, minimized the chance of hyperthermia and thermal stress in the animal, not requiring body cooling. The use of dexmedetomidine in chemical containment protocols for short and minimally invasive procedures allows the subsequent use of its antagonist, atipamezole, contributing to a shorter recovery time, return of the animal’s degree of consciousness and lower incidence of ataxia after assuming a quadrupedal position. The anesthetic protocol used was considered efficient, providing a quick and gentle chemical containment, adequate anesthetic plan and good anesthetic recovery in an adult brown bear from captivity.Keywords:atipamezole, dexmedetomidine, wildlife.Título: Manejo anestésico de um urso pardo (Ursus arctos) cativo submetido a biópsia incisional de nódulo cutâneoDescritores: atipamezole, dexmedetomidine, animais selvagens