The National Commission on Education Excellence and Equity: Hypotheses about Movement Building

In 2013, the congressionally chartered national Commission on Education Equity and Excellence issued unanimous recommendations for P–12 policy changes at the federal, state, and local levels. This remarkably broad consensus, with unusual pragmatism and concreteness, is comprehensive in its scope and predominantly research based. As a clarion call and reform strategy, the commission report, For Each and Every Child, is a successor to A Nation at Risk (1983); the commission’s grand if not grandiose intention was to provide a framework for the next decade or more of nationwide policy struggle. This article, after briefly summarizing the recommendations, focuses on how a movement might be built to advance them

Rapid Reversal of Chondroitin Sulfate Proteoglycan Associated Staining in Subcompartments of Mouse Neostriatum during the Emergence of Behaviour

BACKGROUND: The neostriatum, the mouse homologue of the primate caudate/putamen, is the input nucleus for the basal ganglia, receiving both cortical and dopaminergic input to each of its sub-compartments, the striosomes and matrix. The coordinated activation of corticostriatal pathways is considered vital for motor and cognitive abilities, yet the mechanisms which underlie the generation of these circuits are unknown. The early and specific targeting of striatal subcompartments by both corticostriatal and nigrostriatal terminals suggests activity-independent mechanisms, such as axon guidance cues, may play a role in this process. Candidates include the chondroitin sulfate proteoglycan (CSPG) family of glycoproteins which have roles not only in axon guidance, but also in the maturation and stability of neural circuits where they are expressed in lattice-like perineuronal nets (PNNs). METHODOLOGY/PRINCIPAL FINDINGS: The expression of CSPG-associated structures and PNNs with respect to neostriatal subcompartments has been examined qualitatively and quantitatively using double-labelling for Wisteria floribunda agglutinin (WFA), and the mu-opioid receptor (muOR), a marker for striosomes, at six postnatal ages in mice. We find that at the earliest ages (postnatal day (P)4 and P10), WFA-positive clusters overlap preferentially with the striosome compartment. By P14, these clusters disappear. In contrast, PNNs were first seen at P10 and continued to increase in density and spread throughout the caudate/putamen with maturation. Remarkably, the PNNs overlap almost exclusively with the neostriatal matrix. CONCLUSIONS/SIGNIFICANCE: This is the first description of a reversal in the distribution of CSPG associated structures, as well as the emergence and maintenance of PNNs in specific subcompartments of the neostriatum. These results suggest diverse roles for CSPGs in the formation of functional corticostriatal and nigrostriatal connectivity within the striosome and matrix compartments of the developing caudate/putamen

The Governance Crisis, Legal Theory, and Political Ideology

In addressing the administrative problems of today, the author seeks to challenge the doctrinal separation that has evolved between (1) politics and the partisan struggle over political ideology and public policy, and (2) the realm of legal theory, the source of most prescriptions for the reform of legal doctrines and institutions. Part of this challenge entails sketching his argument, detailed elsewhere, that administrative law fails on its own terms to discipline the arbitrariness of bureaucrats and judges. Administrative law fails, in part, because of a deeply fundamental and conceptually flawed reliance on separation of powers anachronisms

Administrative Law: Rethinking Judicial Control Of Bureaucracy

https://works.swarthmore.edu/alum-books/2301/thumbnail.jp

Changing Places: How Communities Will Improve the Health of Boys of Color

Compiles cross-disciplinary analyses of the challenges boys of color face, how investing in education and community improvement and development could help improve health and well-being outcomes, and the policies and practices needed to support solutions