1,205 research outputs found
Measuring the Impact of Cognitive Behavioral Coaching with Nonverbal Immediacy on the Self-Efficacy of Undergraduate Students in STEM Courses
A quasi-experimental study explored whether the practice of cognitive behavioral coaching with an intentional focus on nonverbal immediacy has an impact on the self-efficacy of undergraduate students taking college-level STEM (Science, Technology, Engineering, and Mathematics) courses. A positive impact to self-efficacy for students who receive the coaching intervention was anticipated. The research took place at a public research university located in the Midwest. Subjects included students who were required to work with a success coach as a condition of their enrollment and/or financial aid eligibility. Information obtained included perception of nonverbal immediacy of the coaches and self-efficacy of the student, as determined by existing assessments called, Nonverbal Immediacy Scale ā Observers and Self-Efficacy for Learning Form ā Abridged version. Success coaches provided the coaching intervention to students through a prescribed protocol of at least four face-to-face meetings throughout the semester with regular contact via email and phone. Students participated in the coaching interventions as mentees. Students received support by coaches to supplement their academic pursuits. Paired t-Tests (see Table 7) did not confirm that there was a significant difference between the pre-assessment scores, and the post-assessment scores; therefore, the null hypotheses were not rejected
Artificial Intelligence and its future potential in lung cancer screening
Artificial intelligence (AI) simulates intelligent behavior as well as critical thinking comparable to a human being and can be used to analyze and interpret complex medical data. The application of AI in imaging diagnostics reduces the burden of radiologists and increases the sensitivity of lung cancer screening so that the morbidity and mortality associated with lung cancer can be decreased. In this article, we have tried to evaluate the role of artificial intelligence in lung cancer screening, as well as the future potential and efficiency of AI in the classification of nodules. The relevant studies between 2010-2020 were selected from the PubMed database after excluding animal studies and were analyzed for the contribution of AI. Techniques such as deep learning and machine learning allow automatic characterization and classification of nodules with high precision and promise an advanced lung cancer screening method in the future. Even though several combination models with high performance have been proposed, an effectively validated model for routine use still needs to be improvised. Combining the performance of artificial intelligence with a radiologistās expertise offers a successful outcome with higher accuracy. Thus, we can conclude that higher sensitivity, specificity, and accuracy of lung cancer screening and classification of nodules is possible through the integration of artificial intelligence and radiology. The validation of models and further research is to be carried out to determine the feasibility of this integration
An evaluation of the evidence of burnout among ultrasound practitioners in Rivers State
BackgroundOccupational burnout has become a critical issue among ultrasound practitioners. Inappropriate management of occupational burnout can lead to serious health problems.AimTo evaluate the evidence of burnout among ultrasound practitioners in Rivers State.Materials and methodsA survey of ultrasound practitioners in selected diagnostic imaging facilities in Port Harcourt and its environs was conducted between November, 2018 and March, 2019 to evaluate the evidence of burnout. A descriptive survey design was employed and selection of the facilities was done using systematic sampling technique. 21 diagnostic imaging facilities were used. Ethical clearance was obtained from Management of the facilities. Data were obtained from structured questionnaires administered to 50 ultrasound practitioners in these facilities, who accepted to participate in the study. The questionnaire surveyed basic demographic data, time taken to get to work, experiences, practices, number of night shifts and other factors that predispose burnout. Data analysis was done using SPSS version 20.ResultsThe factors contributing to burnout among ultrasound practitioners are understaffing leading to work overload and excessive overtime work (41%), hostile interactions with patients' relatives (34%), interactions with colleagues (20%), and conflict with Boss/supervisor (5%). Burnout manifests differently among the practitioners as feelings of: being worn-out and weary (46%), being sick (31%), being emotionally drained (23%).ConclusionUltrasound practitioners in Rivers State suffer high level of burnout. Issues of understaffing and interpersonal communication skills should be addressed in order to minimize the incidence of burnout
Attitudes of advanced Australian medical oncology trainees to rural practice
Aim: To identify the views of medical oncology trainees regarding rural training posts and rural practice overall, and to identify factors that may improve recruitment.
Methods: A questionnaire was posted to all advanced oncology trainees in Australia in June 2006. The trainees were questioned on the perceived advantages and disadvantages of rural practice, their experience during previous rural rotations and potential incentives and barriers in recruiting trainees and specialist oncologists to regional and rural centers.
Results: There was a 60% response rate. Of all participants 58% had considered rural practice. Those with a rural family background were more likely to have considered rural practice. Attitudes based on responses to listed disadvantages and advantages of rural practice were heterogenous. Lifestyle factors seemed to be of particular importance. Although there were perceived deficiencies in opportunities for professional education in rural oncology rotations, 94% felt their rotation had been a positive experience overall and 62% were more likely to consider a rural career following their rural rotation. Improving locum cover for leave was seen as a potential incentive by 97% trainees.
Conclusion: Despite positive attitudes towards rural practice, many barriers exist preventing recruitment of medical oncology trainees to rural areas, in particular lifestyle factors that are difficult to modify. Factors that can be improved include improving access to clinical trials, enabling access to locum cover. Educational opportunities for current rural trainees need to be improved. Further study into potential incentives to enhance rural recruitment is required
The modular synthesis of rare earth-transition metal heterobimetallic complexes utilizing a redox-active ligand
We report a robust and modular synthetic route to heterometallic rare earth-transition metal complexes. We have used the redox-active bridging ligand 1,10-phenathroline-5,6-dione (pd), which has selective N,Nā² or O,Oā² binding sites as the template for this synthetic route. The coordination complexes [Ln(hfac)3(N,Nā-pd)] (Ln = Y [1], Gd [2]; hfac = hexafluoroacetylacetonate) were synthesised in high yield. These complexes have been fully characterised using a range of spectroscopic techniques. Solid state molecular structures of 1 and 2 have been determined by X-ray crystallography and display different pd binding modes in coordinating and non-coordinating solvents. Complexes 1 and 2 are unusually highly coloured in coordinating solvents, for example the vis-NIR spectrum of 1 in acetonitrile displays an electronic transition centred at 587 nm with an extinction coefficient consistent with significant charge transfer. The reaction between 1 and 2 and VCp2 or VCpt2 (Cpt = tetramethylcyclopentadienyl) resulted in the isolation of the heterobimetallic complexes, [Ln(hfac)3(N,Nā²-O,Oā²-pd)VCp2] (Ln = Y [3], Gd [4]) or [Ln(hfac)3(N,Nā²-O,Oā²-pd)VCpt2] (Ln = Y [5], Gd [6]). The solid state molecular structures of 3, 5 and 6 have been determined by X-ray crystallography. The spectroscopic data on 3ā6 are consistent with oxidation of V(II) to V(IV) and reduction of pd to pd2ā in the heterobimetallic complexes. The spin-Hamiltonian parameters from low temperature X-band EPR spectroscopy of 3 and 5 describe a 2A1 ground state, with a V(IV) centre. DFT calculations on 3 are in good agreement with experimental data and confirm the SOMO as the dx2āy2 orbital localised on vanadium
Epigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer Therapy.
Androgen receptor (AR) signaling remains the major oncogenic pathway in prostate cancer (PCa). Androgen-deprivation therapy (ADT) is the principle treatment for locally advanced and metastatic disease. However, a significant number of patients acquire treatment resistance leading to castration resistant prostate cancer (CRPC). Epigenetics, the study of heritable and reversible changes in gene expression without alterations in DNA sequences, is a crucial regulatory step in AR signaling. We and others, recently described the technological advance Chem-seq, a method to identify the interaction between a drug and the genome. This has permitted better understanding of the underlying regulatory mechanisms of AR during carcinogenesis and revealed the importance of epigenetic modifiers. In screening for new epigenomic modifiying drugs, we identified SD-70, and found that this demethylase inhibitor is effective in CRPC cells in combination with current therapies. The aim of this review is to explore the role of epigenetic modifications as biomarkers for detection, prognosis, and risk evaluation of PCa. Furthermore, we also provide an update of the recent findings on the epigenetic key processes (DNA methylation, chromatin modifications and alterations in noncoding RNA profiles) involved in AR expression and their possible role as therapeutic targets
Arch Height in Individuals with Multiple Sclerosis: A Pilot Study
Multiple Sclerosis (MS) is the most common neurological disorder affecting younger adults. MS causes demyelination of nerves in the central nervous system, which impairs the ability of the nerve to conduct its impulse to other nerves and muscles. Over time, weaknesses and sensory deficits in the limbs may lead to structural changes in the musculoskeletal system, such as tightness in certain muscles and joints (calf and ankle) and excessive motion in others (foot and knee). Structural changes in the foot, including arch height and mid-foot flexibility, have yet to be measured or studied in persons with MS.https://ecommons.udayton.edu/dpt_symposium/1009/thumbnail.jp
A Synoptic Review of Mineralogical and Chemical Characteristics of Clays in the Southern Part of Nigeria
This paper reviews the mineralogical and chemical characteristics of clays found in southern part of Nigeria, with a view to determine its usability. The usability of clays, depends on its chemical and mineralogical charactertics, the end product of clay after it is been processed is also based on itās charactertics. From reviewed literature, it was observed that sampled clay within the study area were analyzed using the XRD, XRF and ICPMS method. Further findings also revealed that the dominant clay minerals within the study area include montmorillonite, illite, and kaolinite. On the other hand, it was observed that non-clay minerals such as feldspar, quartz, dickite and many others were found with clay as revealed by several scholars. While chemical charactertics of clay consists mainly of Al2O3, K2O, CaO and SiO2, with other major oxides such as P2O5, MgO, Fe2O3, TiO2, MnO and Na2O. Some trace elements such Be, Ba, Sc, Sr, Zr, V and Y were reported to be present in clays deposit found in selected part of Ogun state. From reviewed articles, it was observed that mineralogical and chemical charactertics of clay make it suitable for pharmaceutical, textile, cosmetic and polymer industries, but considered to be fairly suitable for oil and gas industry
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School-Based Telemedicine Interventions for Asthma: A Systematic Review.
BackgroundSchool health systems are increasingly investing in telemedicine platforms to address acute and chronic illnesses. Asthma, the most common chronic illness in childhood, is of particular interest given its high burden on school absenteeism.ObjectiveConduct a systematic review evaluating impact of school-based telemedicine programs on improving asthma-related outcomes.Data sourcesPubMed, Cochrane CENTRAL, CINAHL, ERIC, PsycINFO, Embase, and Google Scholar.Study eligibility criteriaOriginal research, including quasi-experimental studies, without restriction on the type of telemedicine.ParticipantsSchool-aged pediatric patients with asthma and their families.InterventionsSchool-based telemedicine.Study appraisal and synthesis methodsTwo authors independently screened each abstract, conducted full-text review, assessed study quality, and extracted information. A third author resolved disagreements.ResultsOf 371 articles identified, 7 were included for the review. Outcomes of interest were asthma symptom-free days, asthma symptom frequency, quality of life, health care utilization, school absences, and spirometry. Four of 7 studies reported significant increases in symptom-free days and/or decrease in symptom frequency. Five of 6 reported increases in at least one quality-of-life metric, 2 of 7 reported a decrease in at least 1 health care utilization metric, 1 of 3 showed reductions in school absences, and 1 of 2 reported improvements in spirometry measures.LimitationsVariability in intervention designs and outcome measures make comparisons and quantitative analyses across studies difficult. Only 2 of 7 studies were randomized controlled trials.Conclusions and implications of key findingsHigh-quality evidence supporting the use of school-based telemedicine programs to improve patient outcomes is limited. While available evidence suggests benefit, only 2 comparative trials were identified, and the contribution of telemedicine to these studies' results is unclear
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