28 research outputs found
The Role of the Amygdala in Regulating the Hypothalamic-Pituitary-Adrenal Axis
We investigated the regulatory role of the amygdala upon the function of the hypothalamic-pituitary-adrenal (HPA) axis as measured by median eminence corticotrophin releasing hormone (CRH) content and serum levels of adrenocorticotrophic hormone (ACTH) and corticosterone. Our findings showed that (1) lesions of the central amygdala inhibited the HPA axis responses to a variety of stressful stimuli. (2) Depletion of norepinephrine or serotonin in the amygdala and hypothalamus and local injections of norepinephrine and serotonin receptor antagonists into the central amygdala inhibited the HPA axis responses to neural stress. Norepinephrine and serotonin agonists injected into the amygdala caused an increase in HPA axis activity. The activation of the amygdala facilitated the in vivo release of serotonin from the paraventricular nucleus following electrical stimulation of the brainstem raphe nuclei. (3) Electrical stimulation of the amygdala impaired the glucocorticoid negative feedback action following neural stressful stimuli probably via a decrease in hippocampal corticosteroid receptors
The Involvement of Glucocorticoids and Interleukin-1 in the Regulation of Brain Prostaglandin Production in Response to Surgical Stress
Delayed Effects of Brain Irradiation Part 1: Adrenocortical Axis Dysfunction and Hippocampal Damage in an Adult Rat Model
Mitteleuropa
Au cours des années 1980, la notion de Mitteleuropa, d'une Europe centrale qui n'appartiendrait ni à l'Ouest ni à l'Est, a connu un regain de faveur en Allemagne et en Autriche, mais aussi dans les pays d'Europe centrale se trouvant dans la sphère d'influence soviétique.Quelles sont les possibilités pour voir réémerger ce « continent englouti » qui ne semble plus exister que dans l'imaginaire et la tradition littéraire ? Que signifie la renaissance de ce mythe ? Faut-il s'en réjouir ou s'en inquiéter dans la perspective de l'unification européenne ? Ce sont quelques-unes des questions auxquelles ont tenté de répondre les spécialistes français, allemands autrichiens, polonais etc. réunis à Paris en juin 1987. Les événements de 1989, qu'aucun d'eux n'avait évidemment pu prévoir, ont donné un éclairage nouveau à leurs propos, mais n'ont rien enlevé à leur pertinence.The 1980s saw a renewal of interest for the concept of Mitteleuropa, that of a central Europe that would belong neither to the West nor to the East, in Germany and Austria, but also in the Central European countries that still were under Soviet influence. Analyzing the phenomenon, historians, journalists and politicians have tried to answer here the question of whether to see in this concept an opportunity or an obstacle to European unification