67 research outputs found

    Infusing with ERP Systems: A Longitudinal Investigation of the Impact of Control and Empowerment

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    Organizations have made significant investments in ERP systems with the strategic expectation that employees will utilize this technology to enhance organizational performance. However, research indicates that ERP systems are under-utilized. In order to entangle the challenge of under-utilization, this paper addresses the impact of control and empowerment on infusion – the deep and comprehensive usage of an information system. We apply a longitudinal design with two measurements to research whether the level of infusion of ERP users changes over time, and if so to what extent. Moreover we hypothesize that ‘soft’ characteristics like the organizational position, organization commitment and trust influence the relation between control, empowerment and the level of infusion of the ERP user. A survey was conducted in a large public organization which has been using an ERP system for several years. A sample of 178 matched pairs (For T1 and T2) of ERP system users and their supervisors has been collected. In this research in progress we present the theoretical mechanisms and methodological framework we employed for the data collection

    Opportunities for sexual transmission of antiretroviral drug resistance among HIV-infected patients in care

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    OBJECTIVE: To assess opportunities for transmitted drug resistance (TDR), we examined sexual risk behaviours, HIV viraemia and antiretroviral resistance among patients in care. DESIGN: A retrospective, cross-sectional analysis of clinical cohort data. METHODS: For 244 UNC Center for AIDS Research HIV Clinical Cohort participants, demographic and behavioural data were obtained during in-person interviews between 2000 and 2011. Genotypic resistance tests were interpreted using WHO surveillance drug resistance mutations (SDRMs). Log-linear binomial regression was used to evaluate associations with TDR risk, defined as unprotected sex in the prior 6 months, HIV RNA at least 400 copies/ml and at least one SDRM. RESULTS: Participants included 91 (37%) women and 153 men, of whom 92 (60%) were MSM. Median age was 43 years; 70% were Black (n = 171). Most (97%) were antiretroviral-experienced; 44% had exposure to more than four regimens. Among 204 individuals on antiretrovirals, 42% reported suboptimal adherence and 29% were viraemic. Over half of participants had at least one SDRM (n = 131); 26 (11%) had triple-class resistance. Overall, 70% were sexually active, and 55% used condoms inconsistently. Thirty (12%) reported unprotected sex during periods of drug-resistant viraemia. Higher TDR risk was associated with prior homelessness [adjusted prevalence ratio (aPR) 2.20, 95% confidence interval (CI) 1.16-4.18], active substance use (aPR 3.12, 95% CI 1.47-6.62) and nonsignificantly with MSM (aPR 1.75, 95% CI 0.93-3.28). CONCLUSION: A small but significant proportion of clinic patients with drug-resistant HIV engage in sexual behaviours that place others at risk for TDR. Targeted efforts in secondary prevention could have an impact on TDR incidence, over time

    The effect of tuberculosis treatment on virologic and CD4+ cell count response to combination antiretroviral therapy: a systematic review

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    To determine the impact of tuberculosis (TB) treatment at the time of combination antiretroviral therapy (cART) initiation on virologic and CD4 count response to cART

    Reserva estratégica do medicamento – uma ferramenta (in)vulgar

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    Como têm respondido as Forças Armadas à emergência COVID-19? Que impactos tem esta crise na organização e nas missões militares? Em que medida afetará os recursos que lhes são alocados, ou o peso relativo de diferentes serviços ou áreas internamente? Que lições para a articulação com outras forças de segurança e organizações civis? Estas são algumas das questões que colocámos aos especialistas convidados neste IDN Brief. Para além de participantes nacionais desafiámos também analistas de França, Reino Unido, Holanda, Canadá e África do Sul que nos trazem reflexões a partir da experiência dos seus países. Os desafios que enfrentamos exigem cada vez mais partilha de informação, aprendizagem cruzada e respostas cooperativas.info:eu-repo/semantics/publishedVersio

    A Comparison of Embedded and Nonembedded Print Coverage of the U.S. Invasion and Occupation of Iraq

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    This study examines the impact of embedded versus nonembedded (unilateral) news coverage during the U.S. invasion and occupation of Iraq. A content analysis was conduycted of the Washington Post, New York Times, Los Angeles Times, and Chicago Tribune news coverage of the invasion and occupation examining whether embedded and nonembedded new reports were different and, if so, how. News reports were examined for differences in tone toward the military, trust in the military, framing, and authoritativeness. The results of the study revealed significant differences in overall tone toward the military, trust in military personnel, framing, and authoritativeness between embedded and nonembedded articles.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline

    CDC's COVID-19 International Vaccine Implementation and Evaluation Program and Lessons from Earlier Vaccine Introductions.

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    The US Centers for Disease Control and Prevention (CDC) supports international partners in introducing vaccines, including those against SARS-CoV-2 virus. CDC contributes to the development of global technical tools, guidance, and policy for COVID-19 vaccination and has established its COVID-19 International Vaccine Implementation and Evaluation (CIVIE) program. CIVIE supports ministries of health and their partner organizations in developing or strengthening their national capacities for the planning, implementation, and evaluation of COVID-19 vaccination programs. CIVIE's 7 priority areas for country-specific technical assistance are vaccine policy development, program planning, vaccine confidence and demand, data management and use, workforce development, vaccine safety, and evaluation. We discuss CDC's work on global COVID-19 vaccine implementation, including priorities, challenges, opportunities, and applicable lessons learned from prior experiences with Ebola, influenza, and meningococcal serogroup A conjugate vaccine introductions

    Ethnic conflict and terrorism: The origins and dynamics of civil wars

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    Londonxii, 144 p.: bibl., index; 24 c
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