5 research outputs found
Achieving coordinated national immunity and cholera elimination in Haiti through vaccination: a modelling study
- Author
- Andrea Rinaldo ProfPhD
- Andrew S Azman PhD
- Damiano Pasetto PhD
- Dennis L Chao PhD
- Elizabeth C Lee PhD
- Flavio Finger PhD
- Ira M Longini Jr, ProfPhD
- Javier Perez-Saez PhD
- Jonathan D Sugimoto PhD
- Joseph C Lemaitre MS
- Justin Lessler
- Kenia Vissieres MD
- Laura Matrajt PhD
- Louise C Ivers MD
- M Elizabeth Halloran ProfDSc
- Ralph Ternier MD
- Publication venue
- Publication date
- 01/08/2020
- Field of study
Summary: Background: Cholera was introduced into Haiti in 2010. Since then, more than 820 000 cases and nearly 10 000 deaths have been reported. Oral cholera vaccine (OCV) is safe and effective, but has not been seen as a primary tool for cholera elimination due to a limited period of protection and constrained supplies. Regionally, epidemic cholera is contained to the island of Hispaniola, and the lowest numbers of cases since the epidemic began were reported in 2019. Hence, Haiti may represent a unique opportunity to eliminate cholera with OCV. Methods: In this modelling study, we assessed the probability of elimination, time to elimination, and percentage of cases averted with OCV campaign scenarios in Haiti through simulations from four modelling teams. For a 10-year period from January 19, 2019, to Jan 13, 2029, we compared a no vaccination scenario with five OCV campaign scenarios that differed in geographical scope, coverage, and rollout duration. Teams used weekly department-level reports of suspected cholera cases from the Haiti Ministry of Public Health and Population to calibrate the models and used common vaccine-related assumptions, but other model features were determined independently. Findings: Among campaigns with the same vaccination coverage (70% fully vaccinated), the median probability of elimination after 5 years was 0–18% for no vaccination, 0–33% for 2-year campaigns focused in the two departments with the highest historical incidence, 0–72% for three-department campaigns, and 35–100% for nationwide campaigns. Two-department campaigns averted a median of 12–58% of infections, three-department campaigns averted 29–80% of infections, and national campaigns averted 58–95% of infections. Extending the national campaign to a 5-year rollout (compared to a 2-year rollout), reduced the probability of elimination to 0–95% and the proportion of cases averted to 37–86%. Interpretation: Models suggest that the probability of achieving zero transmission of Vibrio cholerae in Haiti with current methods of control is low, and that bolder action is needed to promote elimination of cholera from the region. Large-scale cholera vaccination campaigns in Haiti would offer the opportunity to synchronise nationwide immunity, providing near-term population protection while improvements to water and sanitation promote long-term cholera elimination. Funding: Bill & Melinda Gates Foundation, Global Good Fund, Institute for Disease Modeling, Swiss National Science Foundation, and US National Institutes of Health
Measurement of the t(t)over-bar production cross section in pp collisions at root s=7 TeV in dilepton final states containing a tau
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdulsalam A
- Adam W
- Adiguzel A
- Adler Volker
- Adzic P
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akin IV
- Albajar C
- Albergo S
- Alda WL
- Aliev T
- Almeida N
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Andrea J
- Andreev V
- Andreev Y
- Anjos TS
- Antunes JR
- Antunovic Z
- Arce P
- Arcidiacono R
- Arfaei H
- Argiro S
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- Asawatangtrakuldee C
- Asghar MI
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- Troendle D
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- Wallny R
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- Waltenberger W
- Walzel G
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- Wang J
- Wang M
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- Wang Z
- Weber H
- Weber HA
- Weber M
- Wehrli L
- Weiler T
- Wendland L
- Wickramage N
- Widl E
- Willmott C
- Wissing C
- Wittmer B
- Wohri HK
- Worm SD
- Wrochna G
- Wulz CE
- Xiao H
- Xu M
- Yazgan Efe
- Yu I
- Yu SS
- Zabi A
- Zaganidis Nikolaos
- Zalewski P
- Zang J
- Zarubin A
- Zeinali M
- Zeise M
- Zeuner WD
- Zhangv Z
- Zhokin A
- Zhu B
- Zhukov V
- Ziebarth EB
- Zito G
- Zotto P
- Zou W
- Zumerle G
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
The top quark pair production cross section is measured in dilepton events with one electron or muon, and one hadronically decaying tau lepton from the decay t (t) over bar -> (l nu(l))((sic)(h)nu((sic)))b (b) over bar, (l = e, mu). The data sample corresponds to an integrated luminosity of 2.0 fb(-1) for the electron channel and 2.2 fb(-1) for the muon channel, collected by the CMS detector at the LHC. This is the first measurement of the t (t) over bar cross section explicitly including tau leptons in proton- proton collisions at root s = 7 TeV. The measured value sigma(t (t) over bar) = 143 +/- 14(stat) +/- 22(syst) +/- 3(lumi) pb is consistent with the standard model predictions
Pathogenic fungi-induced susceptibility is mitigated by mutual Lactobacillus plantarum in the Drosophila melanogaster model
- Author
- A Raman
- AJ Dissanayake
- B Erkosar
- B Lemaitre
- B Lemaitre
- Baocang Ma
- BZ Kacsoh
- C Wang
- CE Schretter
- CH Yang
- E Rosenberg
- F Kempken
- G Sharon
- G Storelli
- G Storelli
- Gabriela Matuoka Chiocchetti
- HA Seddik
- I Iatsenko
- JA Chandler
- JA Chandler
- JE Blum
- JF Christiaens
- JH Ryu
- Jialin Liu
- JP Sousa
- KG Peay
- KL Adair
- LA Ramirez-Camejo
- M Laturney
- M Trinder
- MC Stensmyr
- MR Charbonneau
- MS Lionakis
- N Moleleki
- P Russo
- Peng Bai
- RC Matos
- RM Joseph
- S Caballero Ortiz
- S Moonjely
- S Westfall
- SC Shin
- SE Gilliland
- T Rees
- W Liu
- Wanzhen Su
- Wei Liu
- WJ Lee
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Early Dissimilar Fates of Liver Eicosapentaenoic Acid in Rats Fed Liposomes or Fish Oil and Gene Expression Related to Lipid Metabolism
- Author
- A Belluzzi
- AA Berbert
- AP Halestrap
- Aurélie Battin
- BL Knight
- BO Christophersen
- C Morgan
- C Schacky von
- CA Sindelar
- D Lemaitre-Delaunay
- DD Hong
- DD Lasic
- EB Schmidt
- F Leighton
- F Nacka
- F Nacka
- F Nacka
- H Moriya
- H Sadou
- H Sampath
- H Weissbach
- H Yoshida
- HT Slover
- I Ikeda
- I Ikeda
- I Niot
- J Folch
- JB Robinson
- JF Louet
- JH Song
- JJ Carrero
- Joseph Gresti
- KG Benner
- L Amate
- L Madsen
- M Bronfman
- M Cansell
- M Cansell
- M Ramirez
- Maud Sabine Cansell
- MH Gaiva
- MM Hussain
- MS Lee
- N Shirai
- N Willumsen
- Nicole Combe
- P Chomczynski
- P Degrace
- P Perez-Matute
- Pascal Degrace
- PC Calder
- PG Rittes
- Pierre Clouet
- PT Rose
- RK Berge
- SE Mills
- T Raclot
- VA Ziboh
- VP Carnielli
- X Zheng
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Retinal Glia
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- Aaby AA
- Abbracchio MP
- Abdul Y
- Abrahan CE
- Abu-El-Asrar AM
- Abu-El-Asrar AM
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- Akmayev IG
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- Albini TA
- Albrecht J
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- Alder VA
- Ali BH
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- Büssow H
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- Chan-Ling TL
- Chang CJ
- Chang KC
- Chang L
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- Chang ML
- Chantelau E
- Chao TI
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- Chase J
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- Chavira-Suárez E
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- Chem
- Chen C
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- Cho KS
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- Chong DY
- Christmas NJ
- Christopherson KS
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- Cinatl
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