116,064 research outputs found

    Cranial sutures work collectively to distribute strain throughout the reptile skull

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    The skull is composed of many bones that come together at sutures. These sutures are important sites of growth, and as growth ceases some become fused while others remain patent. Their mechanical behaviour and how they interact with changing form and loadings to ensure balanced craniofacial development is still poorly understood. Early suture fusion often leads to disfiguring syndromes, thus is it imperative that we understand the function of sutures more clearly. By applying advanced engineering modelling techniques, we reveal for the first time that patent sutures generate a more widely distributed, high level of strain throughout the reptile skull. Without patent sutures, large regions of the skull are only subjected to infrequent low-level strains that could weaken the bone and result in abnormal development. Sutures are therefore not only sites of bone growth, but could also be essential for the modulation of strains necessary for normal growth and development in reptiles

    The identification and production of varieties that increase the value of oats as a profitable component of organic production

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    Two experiments, one comprising husked, and the other naked, oats were established at Wakelyns Agroforestry, Suffolk in October 2004 to determine traits and varieties of oats suited to organic systems, and whether growing variety mixtures conferred any advantage. Unselected F2 breeding lines were also included for selection. Husked varieties had relatively higher yields; this may have been partly the result of poor establishment in the naked varieties. Variety height was found to be an important characteristic; tall oat varieties out-yielded the dwarfs. Two of the three variety mixtures containing the naked oat variety Expression yielded 8 and 9 % higher than the average of the component varieties. The data will be verified in the second year of replicated trials (2005/06), which will include the best performing husked and naked varieties, and a mixture of superior IGER-bred F2 breeding lines

    Production of Millisecond Dips in Sco X-1 Count Rates by Dead Time Effects

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    Chang et al. (2006) reported millisecond duration dips in the X-ray intensity of Sco X-1 and attributed them to occultations of the source by small trans-Neptunian objects (TNOs). We have found multiple lines of evidence that these dips are not astronomical in origin, but rather the result of high-energy charged particle events in the RXTE PCA detectors. Our analysis of the RXTE data indicates that at most 10% of the observed dips in Sco X-1 could be due to occultations by TNOs, and, furthermore, we find no positive or supporting evidence for any of them being due to TNOs. We therefore believe that it is a mistake to conclude that any TNOs have been detected via occultation of Sco X-1.Comment: Submitted to ApJ; uses emulateapj.cls, 8 pages with 8 figure

    Experimental criteria for steering and the Einstein-Podolsky-Rosen paradox

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    We formally link the concept of steering (a concept created by Schrodinger but only recently formalised by Wiseman, Jones and Doherty [Phys. Rev. Lett. 98, 140402 (2007)] and the criteria for demonstrations of Einstein-Podolsky-Rosen (EPR) paradox introduced by Reid [Phys. Rev. A, 40, 913 (1989)]. We develop a general theory of experimental EPR-steering criteria, derive a number of criteria applicable to discrete as well as continuous-variables observables, and study their efficacy in detecting that form of nonlocality in some classes of quantum states. We show that previous versions of EPR-type criteria can be rederived within this formalism, thus unifying these efforts from a modern quantum-information perspective and clarifying their conceptual and formal origin. The theory follows in close analogy with criteria for other forms of quantum nonlocality (Bell-nonlocality, entanglement), and because it is a hybrid of those two, it may lead to insights into the relationship between the different forms of nonlocality and the criteria that are able to detect them.Comment: Changed title, updated references, minor corrections, added journal-ref and DO

    Survey of fracture toughness test methods

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    Comprehensive survey presents current methods of fracture toughness testing that are based on linear elastic fracture mechanics. General principles of the basic two dimensional crack stress field model are discussed in relation to real three dimensional specimens. Methods of test instrumentation and procedure are described

    Special colored Superpolynomials and their representation-dependence

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    We introduce the notion of "special superpolynomials" by putting q=1 in the formulas for reduced superpolynomials. In this way we obtain a generalization of special HOMFLY polynomials depending on one extra parameter t. Special HOMFLY are known to depend on representation R in especially simple way: as |R|-th power of the fundamental ones. We show that the same dependence persists for our special superpolynomials in the case of symmetric representations, at least for the 2-strand torus and figure-eight knots. For antisymmetric representations the same is true, but for t=1 and arbitrary q. It would be interesting to find an interpolation between these two relations for arbitrary representations, but no superpolynomails are yet available in this case.Comment: 5 page

    Modulation of endoglin expression in islets of langerhans by VEGF reveals a novel regulator of islet endothelial cell function

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    BACKGROUND: Endoglin/CD105 is an auxiliary receptor for transforming growth factor-β with established roles in vascular remodelling. It has recently been shown that heterozygous endoglin deficiency in mice decreases insulin secretion in an animal model of obesity, highlighting a potential role for endoglin in the regulation of islet function. We have previously identified two different populations of endoglin expressing cells in human and mouse islets which are: (i) endothelial cells (ECs) and (ii) islet mesenchymal stromal cells. The contribution of islet EC endoglin expression to islet development and sensitivity to VEGF is unknown and is the focus of this study. RESULTS: In vitro culture of mouse islets with VEGF164 for 48 h increased endoglin mRNA levels above untreated controls but VEGF did not modulate VEGFR2, CD31 or CD34 mRNA expression or islet viability. Removal of EC-endoglin expression in vivo reduced islet EC area but had no apparent effect on islet size or architecture. CONCLUSION: EC-specific endoglin expression in islets is sensitive to VEGF and plays partial roles in driving islet vascular development, however such regulation appears to be distinct to mechanisms required to modulate islet viability and size

    Evolutionary breeding of healthy wheat: from plot to farm

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    Genetically diverse Composite Cross Populations (CCPs) may be useful in environmentally variable low-input systems as an alternative to pure line varieties. They are formed by hybridising lines with diverse evolutionary origins, bulking the F1 progeny, and allowing natural selection of the progeny in successive crop environments. CCPs derived from 10 high yielding parents (YCCPs), 12 high quality parents (QCCPs), or all 22 parents (YQCCPs), were grown at four sites (2 organic, 2 conventional) in the UK; they are currently (2006) in F5. The YCCPs out yielded the QCCPs, which had better quality characteristics. Although the CCPs performed within the range of the parents, the values obtained were often better than the mean of the parents. Some population samples are now being grown on farms and other sites in England, France, Germany and Hungary

    Fuel quality/processing study. Volume 4: On site processing studies

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    Fuel treated at the turbine and the turbine exhaust gas processed at the turbine site are studied. Fuel treatments protect the turbine from contaminants or impurities either in the upgrading fuel as produced or picked up by the fuel during normal transportation. Exhaust gas treatments provide for the reduction of NOx and SOx to environmentally acceptable levels. The impact of fuel quality upon turbine maintenance and deterioration is considered. On site costs include not only the fuel treatment costs as such, but also incremental costs incurred by the turbine operator if a turbine fuel of low quality is not acceptably upgraded
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