1,802 research outputs found
Composition of Arkansas Grapes During Maturation
Changes in organic acid and glucose content during maturation and ripening of grapes grown in Arkansas in 1973 are shown for four French hybrid varieties, S5279, S10878, SV23- 657, and S13053, and for four rotundifolia varieties, Scuppernong, Tarheel, Fry, and Magoon. In all varieties the concentrations of malates and tartrates were highest in the early stages of berry growth after veraison. During ripening the titratable acidity decreased and Balling and pH measurements increased. Although varieties reached maturity on different dates, changes in parameters followed similar curves typical for grapes of the species but occurring over a short period (Johnson and Nagel 1976, Winkler 1970). Rotundifolia varieties showed unacceptable Balling-acid ratios as well as irregular maturation progress in the study period
Relaxation of surface charge on rotating dielectric spheres: Implications on dynamic electrorheological effects
We have examined the effect of an oscillatory rotation of a polarized
dielectric particle. The rotational motion leads to a re-distribution of the
polarization charge on the surface of the particle. We show that the time
averaged steady-state dipole moment is along the field direction, but its
magnitude is reduced by a factor which depends on the angular velocity of
rotation. As a result, the rotational motion of the particle reduces the
electrorheological effect. We further assume that the relaxation of polarized
charge is arised from a finite conductivity of the particle or host medium. We
calculate the relaxation time based on the Maxwell-Wagner theory, suitably
generalized to include the rotational motion. Analytic expressions for the
reduction factor and the relaxation time are given and their dependence on the
angular velocity of rotation will be discussed.Comment: Accepted for publications by Phys. Rev.
Experimental requirements for Grover's algorithm in optical quantum computation
The field of linear optical quantum computation (LOQC) will soon need a
repertoire of experimental milestones. We make progress in this direction by
describing several experiments based on Grover's algorithm. These experiments
range from a relatively simple implementation using only a single non-scalable
CNOT gate to the most complex, requiring two concatenated scalable CNOT gates,
and thus form a useful set of early milestones for LOQC. We also give a
complete description of basic LOQC using polarization-encoded qubits, making
use of many simplifications to the original scheme of Knill, Laflamme, and
Milburn.Comment: 9 pages, 8 figure
Nonlinear ER effects in an ac applied field
The electric field used in most electrorheological (ER) experiments is
usually quite high, and nonlinear ER effects have been theoretically predicted
and experimentally measured recently. A direct method of measuring the
nonlinear ER effects is to examine the frequency dependence of the same
effects. For a sinusoidal applied field, we calculate the ac response which
generally includes higher harmonics. In is work, we develop a multiple image
formula, and calculate the total dipole moments of a pair of dielectric
spheres, embedded in a nonlinear host. The higher harmonics due to the
nonlinearity are calculated systematically.Comment: Presented at Conference on Computational Physics (CCP2000), held at
Gold Coast, Australia from 3-8, December 200
Multipulse phases in k-mixtures of Bose-Einstein condensates
For a competitive system of k coupled nonlinear Schroedinger equations we
prove the existence, when the competition parameter is large, of positive
radial solutions on R^N. We show that, when the competition parameter goes to
infinity, the profile of each component separates, in many pulses, from the
others. Moreover, we can prescribe the location of such pulses in terms of the
oscillations of the changing-sign solutions of the scalar nonlinear
Schroedinger equation. Within an Hartree-Fock approximation, this provides a
theoretical indication of phase separation into many nodal domains for the
k-mixtures of Bose-Einstein condensates.Comment: 21 page
Human Salmonella Typhi exposure generates differential multifunctional crossâreactive Tâcell memory responses against Salmonella Paratyphi and invasive nontyphoidal Salmonella
Objective
There are no vaccines for most of the major invasive Salmonella strains causing severe infection in humans. We evaluated the specificity of adaptive T memory cell responses generated after Salmonella Typhi exposure in humans against other major invasive Salmonella strains sharing capacity for dissemination.
Methods
T memory cells from eleven volunteers who underwent controlled oral challenge with wt S. Typhi were characterised by flow cytometry for crossâreactive cellular cytokine/chemokine effector responses or evidence of degranulation upon stimulation with autologous Bâlymphoblastoid cells infected with either S. Typhi, Salmonella Paratyphi A (PA), S. Paratyphi B (PB) or an invasive nontyphoidal Salmonella strain of the S. Typhimurium serovar (iNTSTy).
Results
Blood Tâcell effector memory (TEM) responses after exposure to S. Typhi in humans evolve late, peaking weeks after infection in most volunteers. Induced multifunctional CD4+ Th1 and CD8+ TEM cells elicited after S. Typhi challenge were crossâreactive with PA, PB and iNTSTy. The magnitude of multifunctional CD4+ TEM cell responses to S. Typhi correlated with induction of crossâreactive multifunctional CD8+ TEM cells against PA, PB and iNTSTy. Highly multifunctional subsets and T central memory and T effector memory cells that reâexpress CD45 (TEMRA) demonstrated less heterologous Tâcell crossâreactivity, and multifunctional Th17 elicited after S. Typhi challenge was not crossâreactive against other invasive Salmonella.
Conclusion
Gaps in crossâreactive immune effector functions in human Tâcell memory compartments were highly dependent on invasive Salmonella strain, underscoring the importance of strainâdependent vaccination in the design of Tâcellâbased vaccines for invasive Salmonella
Deep geothermal resource assessment of early carboniferous limestones for Central and Southern Great Britain
Early Carboniferous limestones (ECL) host active geothermal systems in Central and Southern Britain. Equivalent rocks have been successfully developed for geothermal energy in Belgium and the Netherlands, but the ECL has yet to be fully assessed as a geothermal resource in Britain. We use established statistical methods to assess the depth, distribution, and geothermal potential of the ECL in Central and Southern Britain. Total heat in place (HIP) resources of 1415 (P10)â1528 (P90) EJ may be present, with a tentative potential recoverable thermal power of 106â222 GW. Further work is needed to understand the resource by identifying areas with sufficient flow rates for successful development such as enhanced permeability zones around faults, fractures or karsts
Recommended from our members
Preliminary technology report for Southern Sector bioremediation
This project was designed to demonstrate the potential of intrinsic bioremediation and phytoremediation in the Southern Sector of the A/M-Area at the Savannah River Site. A subsurface plume of trichloroethylene (TCE) and perchloroethylene (PCE) is present in the Lost Lake aquifer upgradient of the study site and is predicted to impact the area at some point in the future. The surface area along the Lost lake aquifer seep line where the plume is estimated to emerge was identified. Ten sites along the seep line were selected for biological, chemical, and contaminant treatability analyses. A survey was undertaken in this area to to quantify the microbial and plant population known to be capable of remediating TCE and PCE. The current groundwater quality upgradient and downgradient of the zone of influence was determined. No TCE or PCE was found in the soils or surface water from the area tested at this time. A TCE biodegradation treatability test was done on soil from the 10 selected locations. From an initial exposure of 25 ppm of TCE, eight of the samples biodegraded up to 99.9 percent of all the compound within 6 weeks. This biodegradation of TCE appears to be combination of aerobic and anaerobic microbial activity as intermediates that were detected in the treatability test include vinyl chloride (VC) and the dichloroethenes (DCE) 1,2-cis-dichloroethylene and 1,1-dichloroethylene. The TCE biological treatability studies were combines with microbiological and chemical analyses. The soils were found through immunological analysis with direct fluorescent antibodies (DFA) and microbiological analysis with direct fluorescent antibodies (DFA) and microbiological analysis to have a microbial population of methanotrophic bacteria that utilize the enzyme methane monooxygenase (MMO) and cometabolize TCE
The immune evasion roles of Staphylococcus aureus protein A and impact on vaccine development
While Staphylococcus aureus (S. aureus) bacteria are part of the human commensal flora, opportunistic invasion following breach of the epithelial layers can lead to a wide array of infection syndromes at both local and distant sites. Despite ubiquitous exposure from early infancy, the life-long risk of opportunistic infection is facilitated by a broad repertoire of S. aureus virulence proteins. These proteins play a key role in inhibiting development of a long-term protective immune response by mechanisms ranging from dysregulation of the complement cascade to the disruption of leukocyte migration. In this review we describe the recent progress made in dissecting S. aureus immune evasion, focusing on the role of the superantigen, staphylococcal protein A (SpA). Evasion of the normal human immune response drives the ability of S. aureus to cause infection, often recurrently, and is also thought to be a major hindrance in the development of effective vaccination strategies. Understanding the role of S. aureus virulence protein and determining methods overcoming or subverting these mechanisms could lead to much-needed breakthroughs in vaccine and monoclonal antibody development
- âŠ