Generating predictions to aid the scientific discovery process

NGLAUBER is a system which models the scientific discovery of qualitative empirical laws. As such, it falls into the category of scientific discovery systems. However, the program can also be viewed as a conceptual clustering system since it forms classes of objects and characterizes these classes. NGLAUBER differs from existing scientific discovery and conceptual clustering systems in a number of ways: It uses an incremental method to group objects into classes; these classes are formed based on the relationships between objects rather than just the attributes of objects; the system describes the relationships between classes rather than simply describing the classes; and most importantly, NGLAUBER proposes experiments by predicting future data. The experiments help the system guide itself through the search for regularities in the data

Evaluation of Bt cottons for heliothine complex control and yield potential in Tennessee

Cotton insect pests cost fanners beltwide $1.68 billion in 1995 due to yield losses, and insecticide and insecticide application costs. With increased insect resistance and environmental concerns, new and innovative control methods are needed. Several Bt cotton lines have been developed which carry an insecticidal protein from a soil bacterium inside the plant, which is toxic to many lepidopteran cotton pests. Bt cottons were evaluated for resistance to injury from the bollworm, Helicoverpa zea Boddie, and tobacco budworm, Heliothis virescens F., which are lepidopterans collectively called the Heliothine complex. Data indicate that Bt cotton lines suffered significantly less Heliothine complex injury to squares and bolls throughout the season than conventional cultivars. Bt cotton lines did not require insecticide treatments for the Heliothine complex to prevent yield loss. These studies indicate that Bt cottons could play an important role in future cotton pest management and reduce insect control costs in production agriculture

The MSFC Collaborative Engineering Process for Preliminary Design and Concept Definition Studies

This paper describes a collaborative engineering process developed by the Marshall Space Flight Center's Advanced Concepts Office for performing rapid preliminary design and mission concept definition studies for potential future NASA missions. The process has been developed and demonstrated for a broad range of mission studies including human space exploration missions, space transportation system studies and in-space science missions. The paper will describe the design team structure and specialized analytical tools that have been developed to enable a unique rapid design process. The collaborative engineering process consists of integrated analysis approach for mission definition, vehicle definition and system engineering. The relevance of the collaborative process elements to the standard NASA NPR 7120.1 system engineering process will be demonstrated. The study definition process flow for each study discipline will be will be outlined beginning with the study planning process, followed by definition of ground rules and assumptions, definition of study trades, mission analysis and subsystem analyses leading to a standardized set of mission concept study products. The flexibility of the collaborative engineering design process to accommodate a wide range of study objectives from technology definition and requirements definition to preliminary design studies will be addressed. The paper will also describe the applicability of the collaborative engineering process to include an integrated systems analysis approach for evaluating the functional requirements of evolving system technologies and capabilities needed to meet the needs of future NASA programs

Narcissism and altruism among undergraduate business and religion majors

Research has suggested links between narcissism, unethical behavior, and undergraduate business majors. It has been theorized that altruism has a negative relationship with narcissism and research has suggested that religiosity is linked to disapproval of the unethical. Based on this information, the current study hypothesized that business majors would score higher on narcissism than religion majors, measured as selfism using the Phares and Erskine Selfism Test. The current study also hypothesized that religion majors would score higher on altruism than business majors, measured by Johnson\u27s Self-Report Altruism Scale. Forty-one male and 27 female undergraduates majoring in either business or religion participated in the study. Results revealed that business majors did score higher on narcissism measured as selfism, though religion majors did not score higher on altruism

Strategies for Recruiting African American Men into Prostate Cancer Screening Studies

Background Recruitment for research and clinical trials continues to be challenging. Prostate cancer is the most commonly diagnosed cancer in men and disproportionately affects African American men; thus, effective recruitment strategies are essential for this population. Objectives To focus on innovative and effective recruitment strategies for research on prostate cancer with minorities. Methods A systematic description is provided of the recruitment efforts for a hermeneutic phenomenological qualitative study of African American men's experiences in decision-making on whether or not to have a prostate cancer screening. Results Seventeen African American men were enrolled from rural Central Virginia. Recruiting strategies were targeted on places where African American men usually are found, but that are rarely used for recruitment: barbershops, community health centers, and churches. Word-of-mouth was used also, and the majority of the participants (n = 11) were reached through this method. Discussion Recruitment efforts have been noted to be particularly challenging among minorities, for numerous reasons. Making minority recruitment a priority in any research or clinical trial is essential in gaining a representative sample. Word-of-mouth is a powerful tool that is often forgotten, but should be looked at in further detail

QFD analysis of RSRM aqueous cleaners

This paper presents a Quality Function Deployment (QFD) analysis of the final down-selected aqueous cleaners to be used on the Redesigned Solid Rocket Motor (RSRM) program. The new cleaner will replace solvent vapor degreasing. The RSRM Ozone Depleting Compound Elimination program is discontinuing the methyl chloroform vapor degreasing process and replacing it with a spray-in-air aqueous cleaning process. Previously, 15 cleaners were down-selected to two candidates by passing screening tests involving toxicity, flammability, cleaning efficiency, contaminant solubility, corrosion potential, cost, and bond strength. The two down-selected cleaners were further evaluated with more intensive testing and evaluated using QFD techniques to assess suitability for cleaning RSRM case and nozzle surfaces in preparation for adhesive bonding

Antibody responses to a Cryptosporidium parvum rCP15/60 vaccine

Cryptosporidium parvum is a zoonotic apicomplexa-protozoan pathogen that causes gastroenteritis and diarrhoea in mammals worldwide. The organism is transmitted by ingestion of oocysts, which are shed in faeces, and completes its lifecycle in a single host.^1^ C. parvum is ubiquitous on dairy operations worldwide and is one of the leading causes of diarrhoea in calves on these farms.^2,3^ Here, for the first time, we describe the antibody response in a large group of cows to a recombinant C. parvum oocyst surface protein (rCP15/60) vaccine and the antibody response in calves fed rCP15/60-immune colostrum produced by these vaccinated cows. Results of recent genotype surveys indicate that calves are the only major reservoir for C. parvum infections in humans.^4^ Human C. parvum infections are particularly prevalent and often fatal in neonates in developing countries and to immunocompromised people, such as AIDs patients.^4^ Drug therapy against cryptosporidiosis is limited and not wholly efficacious in either humans or calves^5^, making development of an effective vaccine of paramount importance. To date, there is no commercially available effective vaccine against C. parvum, although passive immunization utilizing different zoite surface (glyco)proteins has showed promise.^6-9^ All cows we vaccinated produced an antibody response to the rCP15/60 vaccine and the magnitude of response correlated strongly with the subsequent level of antibody in their colostrum. All calves fed rCP15/60-immune colostrum showed a dose-dependent absorption of antibody. Our results demonstrate that vaccination of cows with rCP15/60 successfully induces antibodies against CP15/60 in their serum and colostrum and that these antibodies are then well absorbed when fed to neonatal calves. With further research, this C. parvum vaccine may well be a practical method of conferring passive protection to calves against cryptosporidiosis. Furthermore, a specifically targeted immune-colostrum may be valuable in protection and treatment of immunocompromised human patients with cryptosporidiosis

Charged-Particle Motion in Electromagnetic Fields Having at Least One Ignorable Spatial Coordinate

We give a rigorous derivation of a theorem showing that charged particles in an arbitrary electromagnetic field with at least one ignorable spatial coordinate remain forever tied to a given magnetic-field line. Such a situation contrasts the significant motions normal to the magnetic field that are expected in most real three-dimensional systems. It is pointed out that, while the significance of the theorem has not been widely appreciated, it has important consequences for a number of problems and is of particular relevance for the acceleration of cosmic rays by shocks.Comment: 7 pages, emulateapj format, including 1 eps figure, to appear in The Astrophysical Journal, Dec. 10 1998 issu