Identification with School and Head Trauma: Parental Perceptions on Student’s Experiences

In the United States 40% of all traumatic brain injuries (TBI) are in children under the age 14 (Broque  et. al 2012). This means a portion of the school age population is exposed to head injury every year. The effect this injury and experience can have on a child varies, but it is important for educators, counselors, and family to understand the psychosocial experiences that follow after TBI. Research has shown that head injury in childhood can have severe psychosocial effects if the injury is not treated, recognized, and planned for (Broque et. al 2012).This research is intended to shed light on what educators, counselors, and families can do to help children who have experienced a TBI. Previous research shows that a loss of sense of self after TBI in three categories; loss of self-knowledge, loss of self by comparison, and loss of self in the eyes of others (Nochi, 1998). This investigation suggests that identification as “disabled” can impact how students identify with their school

Calibration of a Structural Finite Element Model for a Representative Inflatable Space Structure Utilizing Probabilistic Methods and Surrogate Models

A structural finite element model representing a novel inflatable airlock concept has been calibrated using fullscale test data. The concept, denoted as the NonAxisymmetric Inflatable Pressure Structure (NAIPS), was developed under NASAs Minimalistic Advanced Softgoods Hatch (MASH) Program. The current studies extended previous numerical efforts by incorporating the midbody section of the NAIPS to the dome section and calibrating the model with test data using a process that included surrogate models. Brief overviews of the finite element model and calibration process are provided. The completion of the calibration process provided a model that adequately replicated the test data. The successful demonstration of calibration of a finite element model representing an inflatable habitat provides confidence in the ability to use numerical simulations and associated surrogate models to support design and certification of inflatable space habitats

Readability and Interest of Health Occupations Textbooks for Special Needs Learners

The purpose of the study was to evaluate 17 representative health occupations textbooks in terms of reading difficulty, writing style, and interest level for special populations learners. The objective was to identify texts, using six different readability formulas, that were significantly more diificult, thus providing additional obstacles to special populations in their preparation for health occupations careers. Likewise, the relatively easier texts were identified for consideration in text evaluation and selection procedures. Additionally, representative text samples were analyzed with measures of writing style and human interest in order to consider a wider range of selection attributes. Results found that all readability formulas were highly correlated and were effective in discriminating between textbooks of relative ease or difficulty. Writing style and human interest were not strong discriminating factors in identifying accessible texts for special population students. The discussion of these factors includes recommended strategies for implementing textbook evacuation in terms of microcomputer analysis and individual student reading needs for students enrolled in health occupation programs

Probabilistic Sensitivity Analyses Incorporating Surrogate Models for the Structural Response of a Representative Inflatable Space Structure

This study concentrates on results from probabilistic analysis and numerical simulation tools to identify parameter sensitivities and assess surrogate model suitability for a novel inflatable airlock concept, specifically the Non-Axisymmetric Inflatable Pressure Structure (NAIPS) under NASA's Minimalistic Advanced Softgoods Hatch (MASH) Program. The current studies extended the demonstration of probabilistic analysis tools to identify parameter sensitivities by: incorporating nonlinear material load-strain property curves and orthotropic representation of the fabric; and exploring the use of surrogate models to facilitate rapid evaluations as new information becomes available, as well as enable optimizations. The airlock model has been simplified to focus on the end dome section. Brief overviews of the finite element model and associated surrogate models are provided along with the probabilistic sensitivity analysis approaches. Responses of interest include the sensitivities of various loads in the structural elements of the NAIPS to material properties, cord lengths, inflation pressure and friction between softgoods components. The use of surrogate models was explored to facilitate rapid sensitivity evaluations as parameter ranges change. The completion of the sensitivity studies improved understanding of the dependence of load responses to several uncertain parameters and confidence in the ability to use surrogate models to represent the finite element simulations

Managing bereavement in the classroom: a conspiracy of silence?

The ways in which teachers in British schools manage bereaved children are under-reported. This article reports the impact of students' bereavement and their subsequent management in primary and secondary school classrooms in Southeast London. Thirteen school staff working in inner-city schools took part in in-depth interviews that focused on the impact of bereaved children on the school and how teachers responded to these children. All respondents had previously had contact with a local child bereavement service that aims to provide support, advice, and consultancy to children, their parents, and teachers. Interviews were audiotaped, transcribed verbatim, and analyzed using ATLAS-ti. Three main themes were identified from analysis of interview data. Firstly, British society, culture, local communities, and the family were significant influences in these teachers' involvement with bereaved students. Secondly, school staff managed bereaved students through contact with other adults and using practical classroom measures such as "time out" cards and contact books. Lastly, teachers felt they had to be strong, even when they were distressed. Surprise was expressed at the mature reaction of secondary school students to deaths of others. The article recommends that future research needs to concentrate on finding the most effective way of supporting routinely bereaved children, their families, and teachers

SECPS reference manual : organization with membership requirements, standards for peer reviews, administrative, and other peer review procedures

https://egrove.olemiss.edu/aicpa_guides/1318/thumbnail.jp

SECPS reference manual : organization with membership requirements, standards for peer reviews, administrative, and other peer review procedures

https://egrove.olemiss.edu/aicpa_guides/1317/thumbnail.jp

Private Companies Practice Section reference manual

https://egrove.olemiss.edu/aicpa_guides/1897/thumbnail.jp

Testing a MultiTEP-based combination vaccine to reduce Aβ and tau pathology in Tau22/5xFAD bigenic mice.

BackgroundAlzheimer disease (AD) is characterized by the accumulation of beta-amyloid (Aβ) plaques and neurofibrillary tangles composed of hyperphosphorylated tau, which together lead to neurodegeneration and cognitive decline. Current therapeutic approaches have primarily aimed to reduce pathological aggregates of either Aβ or tau, yet phase 3 clinical trials of these approaches have thus far failed to delay disease progression in humans. Strong preclinical evidence indicates that these two abnormally aggregated proteins interact synergistically to drive downstream neurodegeneration. Therefore, combinatorial therapies that concurrently target both Aβ and tau might be needed for effective disease modification.MethodsA combinatorial vaccination approach was designed to concurrently target both Aβ and tau pathologies. Tau22/5xFAD (T5x) bigenic mice that develop both pathological Aβ and tau aggregates were injected intramuscularly with a mixture of two MultiTEP epitope vaccines: AV-1959R and AV-1980R, targeting Aβ and tau, respectively, and formulated in AdvaxCpG, a potent polysaccharide adjuvant. Antibody responses of vaccinated animals were measured by ELISA, and neuropathological changes were determined in brain homogenates of vaccinated and control mice using ELISA and Meso Scale Discovery (MSD) multiplex assays.ResultsT5x mice immunized with a mixture of Aβ- and tau-targeting vaccines generated high Aβ- and tau-specific antibody titers that recognized senile plaques and neurofibrillary tangles/neuropil threads in human AD brain sections. Production of these antibodies in turn led to significant reductions in the levels of soluble and insoluble total tau, and hyperphosphorylated tau as well as insoluble Aβ42, within the brains of bigenic T5x mice.ConclusionsAV-1959R and AV-1980R formulated with AdvaxCpG adjuvant are immunogenic and therapeutically potent vaccines that in combination can effectively reduce both of the hallmark pathologies of AD in bigenic mice. Taken together, these findings warrant further development of this vaccine technology for ultimate testing in human AD