Constraining the Anomalous Microwave Emission Mechanism in the S140 Star Forming Region with Spectroscopic Observations Between 4 and 8 GHz at the Green Bank Telescope

Anomalous microwave emission (AME) is a category of Galactic signals that cannot be explained by synchrotron radiation, thermal dust emission, or optically thin free-free radiation. Spinning dust is one variety of AME that could be partially polarized and therefore relevant for ongoing and future cosmic microwave background polarization studies. The Planck satellite mission identified candidate AME regions in approximately $1^\circ$ patches that were found to have spectra generally consistent with spinning dust grain models. The spectra for one of these regions, G107.2+5.2, was also consistent with optically thick free-free emission because of a lack of measurements between 2 and 20 GHz. Follow-up observations were needed. Therefore, we used the C-band receiver (4 to 8 GHz) and the VEGAS spectrometer at the Green Bank Telescope to constrain the AME mechanism. For the study described in this paper, we produced three band averaged maps at 4.575, 5.625, and 6.125 GHz and used aperture photometry to measure the spectral flux density in the region relative to the background. We found if the spinning dust description is correct, then the spinning dust signal peaks at $30.9 \pm 1.4$ GHz, and it explains the excess emission. The morphology and spectrum together suggest the spinning dust grains are concentrated near S140, which is a star forming region inside our chosen photometry aperture. If the AME is sourced by optically thick free-free radiation, then the region would have to contain HII with an emission measure of $5.27^{+2.5}_{-1.5}\times 10^8$ $\rm{cm^{-6}\,pc}$ and a physical extent of $1.01^{+0.21}_{-0.20} \times 10^{-2}\,\rm{pc}$. This result suggests the HII would have to be ultra or hyper compact to remain an AME candidate.Comment: 21 pages, 14 figures. Submitted to Ap

A Statistical Treatment of the Gamma-Ray Burst "No Host Galaxy" Problem: II. Energies of Standard Candle Bursts

With the discovery that the afterglows after some bursts are coincident with faint galaxies, the search for host galaxies is no longer a test of whether bursts are cosmological, but rather a test of particular cosmological models. The methodology we developed to investigate the original "no host galaxy" problem is equally valid for testing different cosmological models, and is applicable to the galaxies coincident with optical transients. We apply this methodology to a family of models where we vary the total energy of standard candle bursts. We find that total isotropic energies of E<2e52~erg are ruled out while log(E)~53 erg is favored.Comment: To appear in Ap.J., 514, 15 pages + 7 figures, AASTeX 4.0. Revisions are: additional author, updated data, and minor textual change

Soluble tau species, not neurofibrillary aggregates, disrupt neural system integration in a tau transgenic model

Neurofibrillary tangles are a feature of Alzheimer disease and other tauopathies, and while they are generally believed to be markers of neuronal pathology, there is little evidence evaluating whether tangles directly impact neuronal function. To investigate the response of cells in hippocampal circuits to complex behavioral stimuli, we used an environmental enrichment paradigm to induce expression of an immediate-early gene, Arc, in the rTg4510 mouse model of tauopathy. These mice reversibly overexpress P301L tau and exhibit substantial neurofibrillary tangle deposition, neuronal loss, and memory deficits. Employing fluorescent in situ hybridization to detect Arc mRNA, we found that rTg4510 mice have impaired hippocampal Arc expression both without stimulation and in response to environmental enrichment; this likely reflects the combination of functional impairments of existing neurons and loss of neurons. However, tangle-bearing cells were at least as likely as non-tangle-bearing neurons to exhibit Arc expression in response to enrichment. Transgene suppression with doxycycline for 6 weeks resulted in increased percentages of Arc-positive cells in rTg4510 brains compared to untreated transgenics, restoring enrichment-induced Arc mRNA levels to that of wild-type controls despite the continued presence of neurofibrillary pathology. We interpret these data to indicate that soluble tau contributes to impairment of hippocampal function, while tangles do not preclude neurons from responding in a functional circuit

Magnetic field dependence of the internal quality factor and noise performance of lumped-element kinetic inductance detectors

We present a technique for increasing the internal quality factor of kinetic inductance detectors (KIDs) by nulling ambient magnetic fields with a properly applied magnetic field. The KIDs used in this study are made from thin-film aluminum, they are mounted inside a light-tight package made from bulk aluminum, and they are operated near $150 \, \mathrm{mK}$. Since the thin-film aluminum has a slightly elevated critical temperature ($T_\mathrm{c} = 1.4 \, \mathrm{K}$), it therefore transitions before the package ($T_\mathrm{c} = 1.2 \, \mathrm{K}$), which also serves as a magnetic shield. On cooldown, ambient magnetic fields as small as approximately $30 \, \mathrm{\mu T}$ can produce vortices in the thin-film aluminum as it transitions because the bulk aluminum package has not yet transitioned and therefore is not yet shielding. These vortices become trapped inside the aluminum package below $1.2 \, \mathrm{K}$ and ultimately produce low internal quality factors in the thin-film superconducting resonators. We show that by controlling the strength of the magnetic field present when the thin film transitions, we can control the internal quality factor of the resonators. We also compare the noise performance with and without vortices present, and find no evidence for excess noise beyond the increase in amplifier noise, which is expected with increasing loss.Comment: 5 pages, 4 figure

Evaluation of two health status measures in adults with growth hormone deficiency

Objective: To evaluate the psychometric properties of two health status measures for adults with growth hormone deficiency (GHD): Nottingham Health Profile (NHP) and Short Form Health Survey (SF-36). Design: (1) A cross-sectional survey of adults with treated or untreated GHD, to assess reliability and validity of the questionnaires. (2) A randomised, placebo-controlled study of 3 months’ GH withdrawal from GH-treated adults, to assess the questionnaires’ sensitivity to change. Patients: (1) Cross-sectional survey of 157 patients with severe GHD (peak GH Measurements: The NHP and SF-36 were used once in the cross-sectional survey, but twice in the GH-withdrawal study, at baseline and end-point (after 3 months). Results: (1) Cross-sectional survey. Both questionnaires had high internal consistency reliability with subscale Cronbach’s alphas of > 0.73 (NHP) and > 0.78 (SF 36). Calculation of a NHP Total score, occasionally reported in the literature, was shown to be inadvisable. Overall, patients with GHD were found to have significantly worse perceived functioning than the UK general population in SF 36 subscales of General Health, Pain, Social Functioning, Role-Emotional, Role-Physical, and Vitality. Whilst neither questionnaire found significant differences between GH-treated and non-GH-treated patients, there were correlations with duration of GH treatment (p Conclusions: The SF-36 is a better measure than the NHP of health status of people with GHD, owing to its greater discriminatory power with ability to detect lesser degrees of disability. It also has superior sensitivity to some sub-group differences and superior sensitivity to change than the NHP. The SF-36 is highly acceptable to respondents, and has very good internal consistency reliability. The SF-36 is recommended to measure the health status of adults with GHD

Sub-Antarctic and High Antarctic Notothenioid Fishes: Ecology and Adaptational Biology Revealed by the ICEFISH 2004 Cruise of RVIB Nathaniel B. Palmer

The goal of the ICEFISH 2004 cruise, which was conducted on board RVIB Nathaniel B. Palmer and traversed the transitional zones linking the South Atlantic to the Southern Ocean, was to compare the evolution, ecology, adaptational biology, community structure, and population dynamics of Antarctic notothenioid fishes relative to the cool/temperate notothenioids of the sub-Antarctic. To place this work in a comprehensive ecological context, cruise participants surveyed the benthos and geology of the biogeographic provinces and island shelves on either side of the Antarctic Polar Front (or Antarctic Convergence). Genome-enabled comparison of the responses of cold-living and temperate notothenioids to heat stress confirmed the sensitivity of the former to a warming Southern Ocean. Successful implementation of the international and interdisciplinary ICEFISH research cruise provides a model for future exploration of the sub-Antarctic sectors of the Indian and Pacific Oceans

The origin of GEMS in IDPs as deduced from microstructural evolution of amorphous silicates with annealing

We present laboratory studies of the micro-structural evolution of an amorphous ferro-magnesian silicate, of olivine composition, following thermal annealing under vacuum. Annealing under vacuum was performed at temperatures ranging from 870 to 1020 K. After annealing spheroidal metallic nano-particles (2-50 nm) are found within the silicate films. We interpret this microstructure in terms of a reduction of the initial amorphous silicate FeO component, because of the carbon-rich partial pressure in the furnace due to pumping mechanism. Annealing in a controlled oxygen-rich atmosphere confirms this interpretation. The observed microstructures closely resemble those of the GEMS (Glass with Embedded Metal and Sulphides) found in chondritic IDPs (Interplanetary Dust Particles). Since IDPs contain abundant carbonaceous matter, a solid-state reduction reaction may have occurred during heating in the hot inner regions of the proto-solar disc. Related to this, the presence of forsterite grains grown from the amorphous precursor material clearly demonstrates that condensation from gaseous species is not required to explain the occurrence of forsterite around young protostars and in comets. Forsterite grains in these environments can be formed directly in the solid phase by thermal annealing of amorphous ferro-magnesian silicates under reducing conditions.Comment: 4 pages, 2 figures. Accepted for publication A&A Letter to the Edito