A People’s Journey, A Nation’s Past: The National Museum of African American History and Culture

On September 24, 2016, the National Museum of African American History and Culture was opened to the public after almost two decades of planning and more than a century of fighting for a memorial for African Americans. Starting in 1915, when a group of United States Colored Troops sought a memorial for their fallen soldiers, African Americans have worked to have their history remembered on a national scale. A congressional commission for a museum dedicated to African Americans was signed in 1929 by Calvin Coolidge, but the stock market crash in October prevented the museum from being built. The memorial was pushed to the back burner until the Civil Rights Movement of the 1950s and 1960s galvanized the need for a museum again. In 1986, a joint resolution proposed by Representatives Mickey Leland of Texas and John Lewis of Georgia as well as Senator Paul Simon of Illinois marked the beginning of the modern fight for a museum dedicated solely to African Americans. [excerpt

Science, Signals, and Service: The Smithsonian Institution’s Role During the Civil War

Today, the Smithsonian is known for its world-famous exhibits, massive collections of American and natural history artifacts, and its contributions to research around the world. But many people don’t know the role the Smithsonian played during the Civil War. The Smithsonian Castle was finished in 1855 and would become the first home of the research center, the library, and the US Museum. The government recognized the importance of the Institution and, after war was declared, the US Secretary of War ordered Joseph Henry, the Smithsonian Secretary, be issued twelve muskets and 240 rounds of ammunition “for the protection of the Institute against lawless attacks.” The building was in a vulnerable position because it was situated in between the Capitol Building and the White House, and cut off from the rest of the city by the Washington Canal . The Institution was witness to soldiers on parade, as well as to the thousands of wounded soldiers sent back to the city after the First Battle of Bull Run. It suffered no war damage, but suffered from financial woes because Congress was more focused on paying for the war than paying the interest on the Smithson bequest. The inflation and currency devaluation of the era also affected finances

The Conflicting Conflict: Memorialization and Memory of the Great War

July 1st through 3rd, 2013 marked the 150th anniversary of the Battle of Gettysburg. There were an estimated 300,000 to 500,000 visitors to the national park, including as many as 10,000 reenactors. The Civil War sesquicentennial was commemorated from the very beginning, and ended with a reenactment in Appomattox that saw over 6,000 people visit to re-live the end of the American Civil War. On April 9th, bells across the nation, including at Gettysburg College, tolled for 4 minutes to honor the four years the war raged on. Plans were started for the anniversary almost a decade in advance and millions of Americans in commemorating of the war that cost 600,000 Americans their lives. A collective narrative of the war began forming before the surrender was even signed, and while each side had a different memory directly after Appomattox, the settled upon collective narrative still exists today

The Unknown Legacy of the 13th Amendment

On January 31, 1865, Congress passed the 13th Amendment, declaring slavery illegal in the United States. Or so it seemed. The second line of the Amendment, and the most oft unknown, states that slavery can still be used as a form of punishment for crimes, and this practice became widely used as a part of southern backlash to Reconstruction Era policies. After the end of the Civil War, many southern states struggled with rebuilding their infrastructures and government systems. In order to avoid falling into more debt, many of these states turned towards the convict lease system, which claimed that the state prison could lease out its convicts to local companies, usually in industries such as mining, lumbering, and railroad building, to not only house prisoners inexpensively but also regain the means of labor they had with slavery before the Civil War. By adopting the convict lease system, southern states were able to earn revenue and control the suddenly free black population of the South, and with the development of black codes, these states were able to legally disenfranchise African Americans up until the 1930s when Alabama became the last state to abolish the convict lease program. [excerpt

MS-153: The Fritz Draper Hurd ’16 Papers

This collection consists primarily of materials produced by F.D. Hurd himself. The collection includes a memoir draft, photographs of his college experiences, diaries from his college and war time, and various artifacts and memorabilia from Hurd’s time in the military. The collection focuses heavily on Hurd’s college activities and his war service. While the collection does not provide much official information on Hurd’s military service and Gettysburg College experience, it does contain extensive anecdotal information from Hurd’s diaries and remembrances, dictated to his son in the 1970s. There is also a significant amount of information about his time in medical school. Special Collections and College Archives Finding Aids are discovery tools used to describe and provide access to our holdings. Finding aids include historical and biographical information about each collection in addition to inventories of their content. More information about our collections can be found on our website http://www.gettysburg.edu/special_collections/collections/https://cupola.gettysburg.edu/findingaidsall/1172/thumbnail.jp

MS-206: Anti-Communist Publicity Materials

This collection consists primarily of materials produced by the American Legion, the American Coalition, and Patriotic Education, Incorporated for distribution to schools and newspapers, speeches by anti-communist politicians and military members, and publications regarding American nationalism. One of the speeches given is by a notable Gettysburg alumnus, Maj. Gen. Charles Willoughby. The collection focuses heavily on the years 1951 to 1955. While there are multiple anti-communist groups featured, the collection does not provide much background on the organizations themselves. The collection provides an overview of various political issues of the time including the Bricker Amendments, a series of Amendments concerning international treaties and executive power limit that were considered in the 1950s. The opinions of the organizations on immigration laws and Constitutional amendments are also discussed. The collection provides examples of anti-communist propaganda and educational materials provided by each organization. Most of the materials were published by the organizations themselves, although some are from mainstream newspapers. While the collection does provide details on specific government practices, it does not give a wide representation of attitudes amongst anti-communist groups across the United States. The American Coalition section focuses primarily on the Bricker Amendment and immigration reform. Special Collections and College Archives Finding Aids are discovery tools used to describe and provide access to our holdings. Finding aids include historical and biographical information about each collection in addition to inventories of their content. More information about our collections can be found on our website http://www.gettysburg.edu/special_collections/collections/.https://cupola.gettysburg.edu/findingaidsall/1181/thumbnail.jp

Targeted delivery of anti-inflammatory therapy to rheumatoid tissue by fusion proteins containing an IL-4-linked synovial targeting peptide

We provide first-time evidence that the synovial endothelium-targeting peptide (SyETP) CKSTHDRLC successfully delivers conjugated IL-4 to human rheumatoid synovium transplanted into SCID mice. SyETP, previously isolated by in vivo phage display and shown to preferentially localize to synovial xenografts, was linked by recombinant technology to hIL-4 via an MMP-cleavable sequence. Both IL-4 and the MMP-cleavable sequence were shown to be functional. IL-4-SyETP augmented production of IL-1ra by synoviocytes stimulated with IL-1[beta] in a dose-dependent manner. In vivo imaging confirmed increased retention of SyETP-linked-IL-4 in synovial grafts which was enhanced by increasing number of copies (one to three) in the constructs. Strikingly, SyETP delivered bioactive IL-4 in vivo as demonstrated by increased pSTAT6 in synovial grafts. Thus, this study provides proof of concept for peptide-tissue-specific targeted immunotherapy in rheumatoid arthritis. This technology is potentially applicable to other biological therapies providing enhanced potency to inflammatory sites and reducing systemic toxicity

Right to Serve, Right to Lead: Lives and Legacies of the USCT

This is a catalog for an exhibit that follows the evolution of African-American participation in the Civil War, from slaves, to contrabands, to soldiers of the United States Colored Troops (USCT), as well as the lives of black veterans beyond the war, and their ultimate military and social legacy. Using a variety of period items, it creates a narrative that stretches from the Antebellum Period to the current day. In doing so, the exhibit shows how black sacrifice on the battlefield redefined the war\u27s purpose throughout the divided nation, how Jim Crowe suppressed the memory of black participation after Reconstruction, and how the illustrious African-American military tradition left by the USCT endures to this day in their modern heirs

Timing of pubertal stages and breast cancer risk : the Breakthrough Generations Study

Introduction: Breast development and hormonal changes at puberty might affect breast cancer risk, but epidemiological analyses have focussed largely on age at menarche and not at other pubertal stages. Methods: We investigated associations between the timing of pubertal stages and breast cancer risk using data from a cohort study of 104,931 women (Breakthrough Generations Study, UK, 2003–2013). Pubertal variables were reported retrospectively at baseline. Breast cancer risk was analysed using Cox regression models with breast cancer diagnosis as the outcome of interest, attained age as the underlying time variable, and adjustment for potentially confounding variables. Results: During follow-up (mean = 4.1 years), 1094 breast cancers (including ductal carcinoma in situ) occurred. An increased breast cancer risk was associated with earlier thelarche (age when breast growth begins; HR [95% CI] = 1.23 [1.02, 1.48], 1 [referent] and 0.80 [0.69, 0.93] for ≤10, 11–12 and ≥13 years respectively), menarche (initiation of menses; 1.06 [0.93, 1.21], 1 [referent] and 0.78 [0.62, 0.99] for ≤12, 13–14 and ≥15 years), regular periods (0.99 [0.83, 1.18], 1 [referent] and 0.74 [0.59, 0.92] for ≤12, 13–14 and ≥15 years) and age reached adult height (1.25 [1.03, 1.52], 1 [referent] and 1.07 [0.87, 1.32] for ≤14, 15–16 and ≥17 years), and with increased time between thelarche and menarche (0.87 [0.65, 1.15], 1 [referent], 1.14 [0.96, 1.34] and 1.27 [1.04, 1.55] for <0, 0, 1 and ≥2 years), and shorter time between menarche and regular periods (1 [referent], 0.87 [0.73, 1.04] and 0.66 [0.50, 0.88] for 0, 1 and ≥2 years). These associations were generally similar when considered separately for premenopausal and postmenopausal breast cancer. Conclusions: Breast duct development may be a time of heightened susceptibility to risk of carcinogenesis, and greater attention needs to be given to the relation of breast cancer risk to the different stages of puberty

Brief report: how adolescents with ASD process social information in complex scenes. Combining evidence from eye movements and verbal descriptions

We investigated attention, encoding and processing of social aspects of complex photographic scenes. Twenty-four high-functioning adolescents (aged 11–16) with ASD and 24 typically developing matched control participants viewed and then described a series of scenes, each containing a person. Analyses of eye movements and verbal descriptions provided converging evidence that both groups displayed general interest in the person in each scene but the salience of the person was reduced for the ASD participants. Nevertheless, the verbal descriptions revealed that participants with ASD frequently processed the observed person’s emotion or mental state without prompting. They also often mentioned eye-gaze direction, and there was evidence from eye movements and verbal descriptions that gaze was followed accurately. The combination of evidence from eye movements and verbal descriptions provides a rich insight into the way stimuli are processed overall. The merits of using these methods within the same paradigm are discussed