155 research outputs found

    Co-creating a Transdisciplinary Map of Technology-mediated Harms, Risks and Vulnerabilities: Challenges, Ambivalences and Opportunities

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    The phrase "online harms" has emerged in recent years out of a growing political willingness to address the ethical and social issues associated with the use of the Internet and digital technology at large. The broad landscape that surrounds online harms gathers a multitude of disciplinary, sectoral and organizational efforts while raising myriad challenges and opportunities for the crossing entrenched boundaries. In this paper we draw lessons from a journey of co-creating a transdisciplinary knowledge infrastructure within a large research initiative animated by the online harms agenda. We begin with a reflection of the implications of mapping, taxonomizing and constructing knowledge infrastructures and a brief review of how online harm and adjacent themes have been theorized and classified in the literature to date. Grounded on our own experience of co-creating a map of online harms, we then argue that the map -- and the process of mapping -- perform three mutually constitutive functions, acting simultaneously as method, medium and provocation. We draw lessons from how an open-ended approach to mapping, despite not guaranteeing consensus, can foster productive debate and collaboration in ethically and politically fraught areas of research. We end with a call for CSCW research to surface and engage with the multiple temporalities, social lives and political sensibilities of knowledge infrastructures.Comment: 21 pages, 8 figures, to appear in The 26th ACM Conference On Computer-Supported Cooperative Work And Social Computing. October 13-18, 2023. Minneapolis, MN US

    The JCMT Gould Belt Survey: the effect of molecular contamination in SCUBA-2 observations of Orion A

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    Thermal emission from cold dust grains in giant molecular clouds can be used to probe the physical properties, such as density, temperature and emissivity in star-forming regions. We present the SCUBA-2 shared-risk observations at 450 ÎŒ\mum and 850 ÎŒ\mum of the Orion A molecular cloud complex taken at the James Clerk Maxwell Telescope (JCMT). Previous studies showed that molecular emission lines can contribute significantly to the measured fluxes in those continuum bands. We use the HARP 12^{12}CO J=3-2 integrated intensity map for Orion A in order to evaluate the molecular line contamination and its effects on the SCUBA-2 maps. With the corrected fluxes, we have obtained a new spectral index α\alpha map for the thermal emission of dust in the well-known integral-shaped filament. Furthermore, we compare a sample of 33 sources, selected over the Orion A molecular cloud complex for their high 12^{12}CO J=3-2 line contamination, to 27 previously identified clumps in OMC-4. This allows us to quantify the effect of line contamination on the ratio of 850 ÎŒ\mum to 450 ÎŒ\mum flux densities and how it modifies the deduced spectral index of emissivity ÎČ\beta for the dust grains. We also show that at least one Spitzer-identified protostellar core in OMC-5 has a 12^{12}CO J=3-2 contamination level of 16 %. Furthermore, we find the strongest contamination level (44 %) towards a young star with disk near OMC-2. This work is part of the JCMT Gould Belt Legacy Survey.Comment: 13 pages, 6 figures, Accepted for publication in Monthly Notices of the Royal Astronomical Society (MNRAS

    Transcription Is Required to Establish Maternal Imprinting at the Prader-Willi Syndrome and Angelman Syndrome Locus

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    The Prader-Willi syndrome (PWS [MIM 17620]) and Angelman syndrome (AS [MIM 105830]) locus is controlled by a bipartite imprinting center (IC) consisting of the PWS-IC and the AS-IC. The most widely accepted model of IC function proposes that the PWS-IC activates gene expression from the paternal allele, while the AS-IC acts to epigenetically inactivate the PWS-IC on the maternal allele, thus silencing the paternally expressed genes. Gene order and imprinting patterns at the PWS/AS locus are well conserved from human to mouse; however, a murine AS-IC has yet to be identified. We investigated a potential regulatory role for transcription from the Snrpn alternative upstream exons in silencing the maternal allele using a murine transgene containing Snrpn and three upstream exons. This transgene displayed appropriate imprinted expression and epigenetic marks, demonstrating the presence of a functional AS-IC. Transcription of the upstream exons from the endogenous locus correlates with imprint establishment in oocytes, and this upstream exon expression pattern was conserved on the transgene. A transgene bearing targeted deletions of each of the three upstream exons exhibited loss of imprinting upon maternal transmission. These results support a model in which transcription from the Snrpn upstream exons directs the maternal imprint at the PWS-IC

    Combined cognitive and state-control training for children with and without AD/HD: Effects on behaviour, working memory and resting EEG

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    Abstract presented at the 23rd Australasian Society for Psychophysiology Conference, 20-22 Nov 2013, Wollongong, Australi

    New times, new politics: history and memory during the final years of the CPGB

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    This article examines the relationship between collective memory, historical interpretation and political identity. It focuses on the dissolution of the Communist Party of Great Britain (CPGB) as constructed through collective narrative memory, and on Marxist interpretations of history. The divisions within the party and the wider Marxist community, stretching from 1956 until 1991, were often framed around questions of historical interpretation. The events of 1989–1991 created an historical and mnemonic crisis for CPGB members who struggled to reconcile their past identities with their present situation. Unlike the outward-facing revisionism of other political parties, this was an intensely personal affair. The solution for many was to emphasise the need to find new ways to progress socialist aims, without relying on a discredited grand narrative. In contrast, other Communist parties, such as the Communist Party of Britain, which had been established (or ‘re-established’) in 1988, fared rather better. By adhering to the international party line of renewal and continued struggle, the party was able to hold its narrative together, condemning the excesses of totalitarian regimes, while reaffirming the need for international class struggle

    The JCMT Gould Belt Survey: the effect of molecular contamination in SCUBA-2 observations of Orion A

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    JOURThis is the final version of the article. It was first published by Oxford Journals for the Royal Astronomical Society via http://dx.doi.org/ 10.1093/mnras/stv3009Thermal emission from cold dust grains in giant molecular clouds can be used to probe the physical properties, such as density, temperature and emissivity in star-forming regions. We present the Submillimetre Common-User Bolometer Array (SCUBA-2) shared-risk observations at 450 and 850 ÎŒm of the Orion A molecular cloud complex taken at the James Clerk Maxwell Telescope (JCMT). Previous studies showed that molecular emission lines can contribute significantly to the measured fluxes in those continuum bands. We use the Heterodyne Array Receiver Programme 12CO J = 3-2 integrated intensity map for Orion A in order to evaluate the molecular line contamination and its effects on the SCUBA-2 maps. With the corrected fluxes, we have obtained a new spectral index α map for the thermal emission of dust in the well-known integral-shaped filament. Furthermore, we compare a sample of 33 sources, selected over the Orion A molecular cloud complex for their high 12CO J = 3-2 line contamination, to 27 previously identified clumps in OMC 4. This allows us to quantify the effect of line contamination on the ratio of 850-450 ÎŒm flux densities and how it modifies the deduced spectral index of emissivity ÎČ for the dust grains. We also show that at least one Spitzer-identified protostellar core in OMC 5 has a 12CO J = 3-2 contamination level of 16 per cent. Furthermore, we find the strongest contamination level (44 per cent) towards a young star with disc near OMC 2. This work is part of the JCMT Gould Belt Legacy Survey
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