High Reynolds number tests of a NASA SC(3)-0712(B) airfoil in the Langley 0.3-meter transonic cryogenic tunnel

A wind tunnel investigation of a NASA 12-percent-thick, advanced-technology supercritical airfoil was conducted in the Langley 0.3-Meter Transonic Cryogenic Tunnel (TCT). This investigation represents another in the series of NASA/U.S. industry two-dimensional airfoil studies to be completed in the Advanced Technology Airfoil Tests program. Test temperature was varied from 220 K to 96 K at pressures ranging from 1.2 to 4.3 atm. Mach number was varied from 0.60 to 0.80. These variables provided a Reynolds number range from 4,400,000 to 40,000,000 based on a 15.24-cm (6.0-in.) airfoil chord. This investigation was designed to test a NASA advanced-technology airfoil from low to flight-equivalent Reynolds numbers, provide experience in cryogenic wind tunnel model design and testing techniques, and demonstrate the suitability of the 0.3-m TCT as an airfoil test facility. The aerodynamic results are presented as integrated force and moment coefficients and pressure distributions. Data are included which demonstrate the effects of fixed transition, Mach number, and Reynolds number on the aerodynamic characteristics. Also included are remarks on the model design, the model structural integrity, and the overall test experience

Estimation of body density in adolescent athletes

National samples of 141 male and 133 female highly-trained adolescent athletes were studied to derive anthropometric-based equations predicting body density. Anthropometric measures included skinfold thicknesses at seven sites, circum- ferences at 14 sites, and diameters at nine sites. Criterion measures of body density were determined by underwater weighing with corrections for residual lung vol- ume based on the oxygen dilution method. Variable selection procedures included factor analysis followed by forward-stepping regression and polynomial analysis. For both the male and female samples, two quadratic equations utilizing either the sum of three or seven skinfold measures were derived. Within the male sample, high validity coefficients (R = 0.81 - 0.82) and low standard errors (SEE = 0.0055 - 0.0056 g-ml !) were shown with these equations. Similar results were demon- strated with the equations for females (R = 0.82 and SEE = 0.0060 g-ml~ l). Cross- validation on independent samples of male (n = 66) and female (n = 46) adolescent athletes further confirmed these findings. In the cross-validation sample of males, predicted scores were highly correlated with actual body density (r = 0.86 - 0.87) and the total error of prediction ranged from 0.0057 to 0.0061 g-ml~ l. Among the females, these values were r = 0.82 - 0.83 and total error = 0.0058 to 0.0063 g*ml-1. These results indicate that within reasonable limits of error, the sum of three or seven skinfolds may be used to make estimates of the body density of adolescent male or female athlete

The applicability of frame imaging from a spinning spacecraft. Volume 1: Summary report

A detailed study was made of frame-type imaging systems for use on board a spin stabilized spacecraft for outer planets applications. All types of frame imagers capable of performing this mission were considered, regardless of the current state of the art. Detailed sensor models of these systems were developed at the component level and used in the subsequent analyses. An overall assessment was then made of the various systems based upon results of a worst-case performance analysis, foreseeable technology problems, and the relative reliability and radiation tolerance of the systems. Special attention was directed at restraints imposed by image motion and the limited data transmission and storage capability of the spacecraft. Based upon this overall assessment, the most promising systems were selected and then examined in detail for a specified Jupiter orbiter mission. The relative merits of each selected system were then analyzed, and the system design characteristics were demonstrated using preliminary configurations, block diagrams, and tables of estimated weights, volumes and power consumption

Finding relevant free-text radiology reports at scale with IBM Watson Content Analytics: a feasibility study in the UK NHS

Background. Significant amounts of health data are stored as free-text within clinical reports, letters, discharge summaries and notes. Busy clinicians have limited time to read such large amounts of free-text and are at risk of information overload and consequently missing information vital to patient care. Automatically identifying relevant information at the point of care has the potential to reduce these risks but represents a considerable research challenge. One software solution that has been proposed in industry is the IBM Watson analytics suite which includes rule-based analytics capable of processing large document collections at scale. Results. In this paper we present an overview of IBM Watson Content Analytics and a feasibility study using Content Analytics with a large-scale corpus of clinical free-text reports within a UK National Health Service (NHS) context. We created dictionaries and rules for identifying positive incidence of hydronephrosis and brain metastasis from 5.6m radiology reports and were able to achieve 94% precision, 95% recall and 89% precision, 94% recall respectively on a sample of manually annotated reports. With minor changes for US English we applied the same rule set to an open access corpus of 0.5m radiology reports from a US hospital and achieved 93% precision, 94% recall and 84% precision, 88% recall respectively. Conclusions. We were able to implement IBM Watson within a UK NHS context and demonstrate effective results that could provide clinicians with an automatic safety net which highlights clinically important information within free-text documents. Our results suggest that currently available technologies such as IBM Watson Content Analytics already have the potential to address information overload and improve clinical safety and that solutions developed in one hospital and country may be transportable to different hospitals and countries. Our study was limited to exploring technical aspects of the feasibility of one industry solution and we recognise that healthcare text analytics research is a fast moving field. That said, we believe our study suggests that text analytics is sufficiently advanced to be implemented within industry solutions that can improve clinical safety

Generalized seniority from random Hamiltonians

We investigate the generic pairing properties of shell-model many-body Hamiltonians drawn from ensembles of random two-body matrix elements. Many features of pairing that are commonly attributed to the interaction are in fact seen in a large part of the ensemble space. Not only do the spectra show evidence of pairing with favored J=0 ground states and an energy gap, but the relationship between ground state wave functions of neighboring nuclei show signatures of pairing as well. Matrix elements of pair creation/annihilation operators between ground states tend to be strongly enhanced. Furthermore, the same or similar pair operators connect several ground states along an isotopic chain. This algebraic structure is reminiscent of the generalized seniority model. Thus pairing may be encoded to a certain extent in the Fock space connectivity of the interacting shell model even without specific features of the interaction required.Comment: 10 pages, 7 figure

An artificially generated atmosphere near a lunar base

We discuss the formation of an artificial atmosphere generated by vigorous lunar base activity in this paper. We developed an analytical, steady-state model for a lunar atmosphere based upon previous investigations of the Moon's atmosphere from Apollo. Constant gas-injection rates, ballistic trajectories, and a Maxwellian particle distribution for an oxygen-like gas are assumed. Even for the extreme case of continuous He-3 mining of the lunar regolith, we find that the lunar atmosphere would not significantly degrade astronomical observations beyond about 10 km from the mining operation

Structural and Magnetic Dynamics in the Magnetic Shape Memory Alloy Ni2_2MnGa

Magnetic shape memory Heusler alloys are multiferroics stabilized by the correlations between electronic, magnetic and structural order. To study these correlations we use time resolved x-ray diffraction and magneto-optical Kerr effect experiments to measure the laser induced dynamics in a Heusler alloy Ni$_2$MnGa film and reveal a set of timescales intrinsic to the system. We observe a coherent phonon which we identify as the amplitudon of the modulated structure and an ultrafast phase transition leading to a quenching of the incommensurate modulation within 300~fs with a recovery time of a few ps. The thermally driven martensitic transition to the high temperature cubic phase proceeds via nucleation within a few ps and domain growth limited by the speed of sound. The demagnetization time is 320~fs, which is comparable to the quenching of the structural modulation.Comment: 5 pages, 3 figures. Supplementary materials 5 pages, 5 figure

Novel treatment strategies for chronic kidney disease: insights from the animal kingdom

Many of the >2 million animal species that inhabit Earth have developed survival mechanisms that aid in the prevention of obesity, kidney disease, starvation, dehydration and vascular ageing; however, some animals remain susceptible to these complications. Domestic and captive wild felids, for example, show susceptibility to chronic kidney disease (CKD), potentially linked to the high protein intake of these animals. By contrast, naked mole rats are a model of longevity and are protected from extreme environmental conditions through mechanisms that provide resistance to oxidative stress. Biomimetic studies suggest that the transcription factor nuclear factor erythroid 2-related factor 2 (NRF2) offers protection in extreme environmental conditions and promotes longevity in the animal kingdom. Similarly, during months of fasting, immobilization and anuria, hibernating bears are protected from muscle wasting, azotaemia, thrombotic complications, organ damage and osteoporosis - features that are often associated with CKD. Improved understanding of the susceptibility and protective mechanisms of these animals and others could provide insights into novel strategies to prevent and treat several human diseases, such as CKD and ageing-associated complications. An integrated collaboration between nephrologists and experts from other fields, such as veterinarians, zoologists, biologists, anthropologists and ecologists, could introduce a novel approach for improving human health and help nephrologists to find novel treatment strategies for CKD